Author details

Full Name

Alexander R Judkins

Affiliation

ORCID

Career Start Year

1995

Papers

120

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37204254	Addendum: Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy.	Oncotarget	2023
37584601	Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.	Cancer Discov	2023
37094128	Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas.	Proc Natl Acad Sci U S A	2023
35168418	Intraoperative Diagnosis for Pediatric Brain Tumors.	Pediatr Dev Pathol	2022
36268104	Quantitative Nuclear Histomorphometry Predicts Molecular Subtype and Clinical Outcome in Medulloblastomas: Preliminary Findings.	J Pathol Inform	2022
36620600	Novel MRI deformation-heterogeneity radiomic features are associated with molecular subgroups and overall survival in pediatric medulloblastoma: Preliminary findings from a multi-institutional study.	Front Oncol	2022
33872110	A Practical Approach to the Evaluation and Diagnosis of Pediatric CNS Tumors.	Pediatr Dev Pathol	2022
35168419	Evaluation and Diagnosis of Central Nervous System Embryonal Tumors (Non-Medulloblastoma).	Pediatr Dev Pathol	2022
34806958	Whose Data, Whose Risk? Omics Privacy Concerns Should be Defined by Individuals, not Researchers.	American Journal of Bioethics	2021
34125658	Rapidly emerging SARS-CoV-2 B.1.1.7 sub-lineage in the United States of America with spike protein D178H and membrane protein V70L mutations.	Emerg Microbes Infect	2021
33688673	Persistent SARS-CoV-2 infection and increasing viral variants in children and young adults with impaired humoral immunity.	medRxiv	2021
33896413	Emerging variants of concern in SARS-CoV-2 membrane protein: a highly conserved target with potential pathological and therapeutic implications.	Emerg Microbes Infect	2021
34162441	Autopsy findings of previously described case of diffuse intrinsic pontine glioma-like tumor with EZHIP expression and molecular features of PFA ependymoma.	Acta Neuropathol Commun	2021
33948563	Clinical utility of comprehensive genomic profiling in central nervous system tumors of children and young adults.	Neurooncol Adv	2021
33938067	Histopathological patterns in atypical teratoid/rhabdoid tumors are related to molecular subgroup.	Brain Pathol	2021
33915337	Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series.	EBioMedicine	2021
33355066	Deep hypothermic circulatory arrest in cyanotic piglets is associated with increased neuronal necrosis.	Cardiol Young	2021
34613815	Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.	Sci Transl Med	2021
34644147	Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas.	Sci Transl Med	2021
32558936	SMARCB1 loss induces druggable cyclin D1 deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumors.	J Pathol	2020
31912158	SWI/SNF complex heterogeneity is related to polyphenotypic differentiation, prognosis, and immune response in rhabdoid tumors.	Neuro Oncol	2020
32197665	Diffuse intrinsic pontine glioma-like tumor with EZHIP expression and molecular features of PFA ependymoma.	Acta Neuropathol Commun	2020
32129445	Advancing biology-based therapeutic approaches for atypical teratoid rhabdoid tumors.	Neuro Oncol	2020
32105509	Efficacy of High-Dose Chemotherapy and Three-Dimensional Conformal Radiation for Atypical Teratoid/Rhabdoid Tumor: A Report From the Children's Oncology Group Trial ACNS0333.	J Clin Oncol	2020
34095334	High Prevalence of SARS-CoV-2 Genetic Variation and D614G Mutation in Pediatric Patients With COVID-19.	Open Forum Infect Dis	2020
33013809	Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country.	Front Microbiol	2020
32730180	Reply to S.A. Upadhyaya.	J Clin Oncol	2020
30718506	SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer.	Nat Commun	2019
30728904	Sustained response of three pediatric BRAF<sup>V600E</sup> mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy.	Oncotarget	2019
30948375	Pediatric Atypical Teratoid/Rhabdoid Tumors of the Brain: Identification of Metabolic Subgroups Using In Vivo <sup>1</sup>H-MR Spectroscopy.	AJNR Am J Neuroradiol	2019
30718512	CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary.	Nat Commun	2019
29581140	Transmission of a <i>TP53</i> germline mutation from unaffected male carrier associated with pediatric glioblastoma in his child and gestational choriocarcinoma in his female partner.	Cold Spring Harb Mol Case Stud	2018
30138724	OncoKids: A Comprehensive Next-Generation Sequencing Panel for Pediatric Malignancies.	J Mol Diagn	2018
29679371	Fitting the epigenome into the picture: methylation classification for paediatric brain tumours.	Neuropathol Appl Neurobiol	2018
28733933	Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome.	Acta Neuropathol	2017
28824165	Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development.	Nat Commun	2017
27960086	Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.	Cancer Cell	2016
27155049	A Rapid and Sensitive Next-Generation Sequencing Method to Detect RB1 Mutations Improves Care for Retinoblastoma Patients and Their Families.	J Mol Diagn	2016
26254476	Molecular subgroups of medulloblastoma identification using noninvasive magnetic resonance spectroscopy.	Neuro Oncol	2016
27881822	Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas.	Sci Transl Med	2016
26212717	Hypoxia Induces Production of L-2-Hydroxyglutarate.		2015
25882982	Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.	Lancet Oncol	2015
25344580	Tumor-associated macrophages in SHH subgroup of medulloblastomas.	Clin Cancer Res	2015
26605127	Ganglioglioma of the Spinal Cord.	Journal of Clinical Imaging Science	2015
24998913	Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation.	Cell Metab	2014
25246033	Pathology and diagnosis of SMARCB1-deficient tumors.	Cancer Genet	2014
25200322	A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas.	Acta Neuropathol	2014
25242145	Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion.	Mol Cell	2014
23414300	Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas.	Brain Pathol	2013
23765250	The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas.	Mod Pathol	2013