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Author Details

Kathleen M Giacomini
University of California San Francisco
1978
343
72
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37474759Cardiac contraction and relaxation are regulated by distinct subcellular cAMP pools.Nat Chem Biol2024
36525397Identification of Genetic Variation Influencing Metformin Response in a Multiancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP).Diabetes2023
37623829The Impacts of Slc19a3 Deletion and Intestinal SLC19A3 Insertion on Thiamine Distribution and Brain Metabolism in the Mouse.Metabolites2023
37657924TICBase: Integrated Resource for Data on Drug and Environmental Chemical Interactions with Mammalian Drug Transporters.Clin Pharmacol Ther2023
37609337Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates.bioRxiv2023
37971383Ensuring Transparency and Quality of Clinical Trial Reporting in Clinical Pharmacology & Therapeutics: Prospective Trial Registration and Compliance with Reporting Guidelines Are Required for all Clinical Trials.Clin Pharmacol Ther2023
37151050The Effect of Trimethoprim on Thiamine Absorption: A Transporter-Mediated Drug-Nutrient Interaction.Clin Pharmacol Ther2023
37335056Trends in Clinical Pharmacology and Therapeutics.Clin Pharmacol Ther2023
37069736Biomarkers Come of Age in Clinical Pharmacology.Clin Pharmacol Ther2023
37333090The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics.bioRxiv2023
37198956Characterization of P-glycoprotein orthologs from human, sheep, pig, dog, and cat.J Vet Pharmacol Ther2023
36798016Diversity, Equity, and Inclusion: Translating Clinical Pharmacology for All.Clin Pharmacol Ther2023
35134255The Pandemic as a Catalyst for Disruptive Innovation in Clinical Pharmacology.Clin Pharmacol Ther2022
35349657Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682.Diabetes Care2022
35501614A Critical Overview of the Biological Effects of Excipients (Part I): Impact on Gastrointestinal Absorption.AAPS J2022
35488474New and Emerging Research on Solute Carrier and ATP Binding Cassette Transporters in Drug Discovery and Development: Outlook From the International Transporter Consortium.Clin Pharmacol Ther2022
35989454More Than Pharmacokinetics: Transporters in Clinical Pharmacology.Clin Pharmacol Ther2022
36343260Functional genomics of OCTN2 variants informs protein-specific variant effect predictor for Carnitine Transporter Deficiency.Proc Natl Acad Sci U S A2022
35152405The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms.Clin Pharmacol Ther2022
35089508High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3.Pharm Res2022
32910949Drug Metabolites Potently Inhibit Renal Organic Anion Transporters, OAT1 and OAT3.J Pharm Sci2021
33492663A New Era in Pharmacovigilance: Toward Real-World Data and Digital Monitoring.Clin Pharmacol Ther2021
33649974The Effects of Genetic Mutations and Drugs on the Activity of the Thiamine Transporter, SLC19A2.AAPS J2021
33759449Drugs in COVID-19 Clinical Trials: Predicting Transporter-Mediated Drug-Drug Interactions Using In Vitro Assays and Real-World Data.Clin Pharmacol Ther2021
33931953Oxypurinol pharmacokinetics and pharmacodynamics in healthy volunteers: Influence of BCRP Q141K polymorphism and patient characteristics.Clin Transl Sci2021
33798442Opportunities and challenges for the computational interpretation of rare variation in clinically important genes.Am J Hum Genet2021
34921098Emerging Roles of the Human Solute Carrier 22 Family.Drug Metab Dispos2021
34528148Interaction of Commonly Used Oral Molecular Excipients with P-glycoprotein.AAPS J2021
34607834Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas.Diabetes Care2021
34318925Advancing Precision Medicine Through the New Pharmacogenomics Global Research Network.Clin Pharmacol Ther2021
33434947Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins.Br J Pharmacol2021
33096136A Tribute to Professor Per Artursson - Scientist, Explorer, Mentor, Innovator, and Giant in Pharmaceutical Research.J Pharm Sci2021
32350861COVID-19: A Defining Moment for Clinical Pharmacology?Clin Pharmacol Ther2020
31696505Global Pharmacogenomics Within Precision Medicine: Challenges and Opportunities.Clin Pharmacol Ther2020
31990564Interactions of Oral Molecular Excipients with Breast Cancer Resistance Protein, BCRP.Mol Pharm2020
31863685Clinical Pharmacology & Therapeutics 2030.Clin Pharmacol Ther2020
31774556Expanding Precompetitive Multisector Collaborations to Advance Drug Development and Pharmacogenomics.Clin Pharmacol Ther2020
31764942Drug-nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3).Am J Clin Nutr2020
33124720Deorphaning a solute carrier 22 family member, SLC22A15, through functional genomic studies.FASEB J2020
32571913Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives.Proc Natl Acad Sci U S A2020
32703874The activities of drug inactive ingredients on biological targets.Science2020
32675325Neural production of kynurenic acid in <i>Caenorhabditis elegans</i> requires the AAT-1 transporter.Genes Dev2020
32727913Scientific considerations for global drug development.Sci Transl Med2020
32390146Oral Anticoagulants and Precision Medicine: Something Old, Something New.Clin Pharmacol Ther2020
32304600Novel Technologies Enable Mechanistic Understanding and Modeling of Drug Exposure and Response.Clin Pharmacol Ther2020
30663035Impact of Pharmaceutical Excipients on Oral Drug Absorption: A Focus on Intestinal Drug Transporters.Clin Pharmacol Ther2019
31415568A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster.PLoS Genet2019
31553721Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies.PLoS Genet2019
31248771l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan.Bioorg Med Chem Lett2019
31127606A Comprehensive Analysis of Ontogeny of Renal Drug Transporters: mRNA Analyses, Quantitative Proteomics, and Localization.Clin Pharmacol Ther2019
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Collaborators

University of California San Francisco
Co-authored papers 82
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 34
Center for Visualization, Washington State University
Co-authored papers 32
University of California San Francisco
Co-authored papers 32
Co-authored papers 23
University of California san francisco
Co-authored papers 21
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 21
University of California San Francisco
Co-authored papers 19
University of California San Francisco
Co-authored papers 18
University of California san francisco
Co-authored papers 17
University of California San Francisco
Co-authored papers 17
University of Toledo
Co-authored papers 16
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 16
Tsinghua University
Co-authored papers 15
Stanford University
Co-authored papers 15
Co-authored papers 15
Eshelman School of Pharmacy, University of North Carolina
Co-authored papers 14
University of California San Francisco (UCSF)
Co-authored papers 14
Vanderbilt University Medical Center
Co-authored papers 13
Department of Drug Metabolism and Pharmacokinetics, Inc.
Co-authored papers 13
Schools of Pharmacy and Medicine, University of California san francisco
Co-authored papers 12
University of California San Francisco
Co-authored papers 12
Amunix Pharmaceuticals
Co-authored papers 11
Gilead Sciences Inc.
Co-authored papers 10
Stanford University
Co-authored papers 10
Stanford University
Co-authored papers 9
Co-authored papers 9
Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 9
Departments of Pharmaceutical Sciences.
Co-authored papers 9
Children's Hospital Oakland Research Institute
Co-authored papers 9