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Author Details

Gunes Gundem
Memorial Sloan Kettering Cancer Center
2010
56
33
PMIDPaper TitleJournal TitlePublished Year
38047392NIPBL::NACC1 Fusion Hepatic Carcinoma.Am J Surg Pathol2024
37652664The importance of escalating molecular diagnostics in patients with low-grade pediatric brain cancer.Cold Spring Harb Mol Case Stud2024
36686814Skeletal muscle metastases in neuroblastoma share common progenitors with primary tumor and biologically resemble stage MS disease.Front Oncol2023
37812025Subclonal Somatic Copy-Number Alterations Emerge and Dominate in Recurrent Osteosarcoma.Cancer Res2023
37169874Clonal evolution during metastatic spread in high-risk neuroblastoma.Nat Genet2023
36711976Subclonal somatic copy number alterations emerge and dominate in recurrent osteosarcoma.bioRxiv2023
35078859Bone Marrow Surveillance of Pediatric Cancer Survivors Identifies Clones that Predict Therapy-Related Leukemia.Clin Cancer Res2022
35585047Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers.Nat Commun2022
33473129Author Correction: Accelerated single cell seeding in relapsed multiple myeloma.Nat Commun2021
33564192Author Correction: Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes.Nat Med2021
33753552Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor.Mol Cancer Res2021
34331515Association of BRAF V600E mutations with vasoactive intestinal peptide syndrome in MYCN-amplified neuroblastoma.Pediatr Blood Cancer2021
32680998Accelerated single cell seeding in relapsed multiple myeloma.Nat Commun2020
33256603Isabl Platform, a digital biobank for processing multimodal patient data.BMC Bioinformatics2020
33033260Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy.Nat Commun2020
33106634Cancer therapy shapes the fitness landscape of clonal hematopoiesis.Nat Genet2020
33392515Revealing the impact of structural variants in multiple myeloma.Blood Cancer Discov2020
32747829Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes.Nat Med2020
30877085Patient-Driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel <i>AKT1</i> Fusion-Driven Cancer.Cancer Discov2019
30924768Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma.Elife2019
29662167Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.Nat Genet2018
30552129A recurrent novel <i>MGA-NUTM1</i> fusion identifies a new subtype of high-grade spindle cell sarcoma.Cold Spring Harb Mol Case Stud2018
30304655Classification and Personalized Prognosis in Myeloproliferative Neoplasms.N Engl J Med2018
28614790Genomic landscape and evolution of metastatic chromophobe renal cell carcinoma.JCI Insight2017
35172488Persistent Severe Hyperlactatemia and Metabolic Derangement in Lethal SDHB-Mutated Metastatic Kidney Cancer: Clinical Challenges and Examples of Extreme Warburg Effect.JCO Precis Oncol2017
29623306Successful Targeted Therapy of Refractory Pediatric <i>ETV6-NTRK3</i> Fusion-Positive Secretory Breast Carcinoma.JCO Precis Oncol2017
28945760Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.PLoS Genet2017
28810143Genomic Evolution of Breast Cancer Metastasis and Relapse.Cancer Cell2017
26926684Genomic Characterization of Primary Invasive Lobular Breast Cancer.J Clin Oncol2016
27615322Mutational signatures of ionizing radiation in second malignancies.Nat Commun2016
27197245Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.Genome Res2016
27276561Genomic Classification and Prognosis in Acute Myeloid Leukemia.N Engl J Med2016
25381129Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol.Haematologica2015
26099045Subclonal diversification of primary breast cancer revealed by multiregion sequencing.Nat Med2015
25830880The evolutionary history of lethal metastatic prostate cancer.Nature2015
25850943Uncovering the genomic heterogeneity of multifocal breast cancer.J Pathol2015
26018901Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.Nat Genet2015
25963125Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.Genome Res2015
25730763Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.Nat Genet2015
25428260KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype.Leukemia2015
25586381Mutation detection in formalin-fixed prostate cancer biopsies taken at the time of diagnosis using next-generation DNA sequencing.J Clin Pathol2015
24413735RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.Nat Genet2014
25271376Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer.Elife2014
25043003Genome sequencing of normal cells reveals developmental lineages and mutational processes.Nature2014
25082706Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.Science2014
24633157Recurrent PTPRB and PLCG1 mutations in angiosarcoma.Nat Genet2014
24030381Clinical and biological implications of driver mutations in myelodysplastic syndromes.Blood2013
24325359Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.N Engl J Med2013
24162739Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.Nat Genet2013
22179826p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes.Oncogene2012
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Collaborators

Peter J Campbell
Wellcome Sanger Institute
Co-authored papers 22
David C Wedge
Manchester Cancer Research Centre, University of Manchester
Co-authored papers 17
Peter Van Loo
The Francis Crick Institute
Co-authored papers 16
Adam Butler
Wellcome Sanger Institute
Co-authored papers 15
Jon Teague
Wellcome Sanger Institute
Co-authored papers 14
Michael R Stratton
Wellcome Sanger Institute
Co-authored papers 13
Laura Mudie
Wellcome Trust Sanger Institute
Co-authored papers 12
Ultan McDermott
Wellcome Sanger Institute
Co-authored papers 12
Keiran Raine
Wellcome Sanger Institute
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Serena Nik-Zainal
Early Cancer Institute, University of Cambridge
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Ludmil B Alexandrov
Moores Cancer Center, university of california san diego
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Sarah O'Meara
Clinical Research Facility, Mercy University Hospital
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Colin S Cooper
Norwich Medical School, University of East Anglia
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David Jones
Wellcome Sanger Institute
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George Steven Bova
Prostate Cancer Research Center, Tampere University and Tays Cancer Center
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Patrick S Tarpey
Wellcome Trust Sanger Institute
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Inigo Martincorena
Wellcome Sanger Institute
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Daniel S Brewer
University of Washington, USA Institute for Stem Cell and Regenerative Medicine
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Christopher S Foster
The Institute of Cancer Research
Co-authored papers 9
Moritz Gerstung
German Cancer Research Centre DKFZ
Co-authored papers 9
Stuart McLaren
Wellcome Trust Sanger Institute
Co-authored papers 9
Manasa Ramakrishna
Co-authored papers 9
Rosalind A Eeles
The Institute of Cancer Research
Co-authored papers 9
David E Neal
University of Oxford, John Radcliffe Hospital
Co-authored papers 9
Hayley C Whitaker
University College London
Co-authored papers 7
Adrienne M Flanagan
University College London, UCL Cancer Institute
Co-authored papers 7
Andy G Lynch
University of St Andrews
Co-authored papers 7
Nuria Lopez-Bigas
Universitat Pompeu Fabra
Co-authored papers 7
Susanna L Cooke
Institute of Cancer Sciences, University of Glasgow
Co-authored papers 7
Charlie E Massie
University of Cambridge
Co-authored papers 7
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