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Author Details

Joseph Y Cheung
1977
198
50
PMIDPaper TitleJournal TitlePublished Year
34997361Pepducin ICL1-9-Mediated β2-Adrenergic Receptor-Dependent Cardiomyocyte Contractility Occurs in a G Protein/ROCK/PKD-Sensitive Manner.Cardiovascular Drugs and Therapy2023
37502932Mitochondrial Magnesium is the cationic rheostat for MCU-mediated mitochondrial Ca uptake.2023
37547075Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the Heart.2023
36980278BAG3: Nature's Quintessential Multi-Functional Protein Functions as a Ubiquitous Intra-Cellular Glue.Cells2023
33892492Epidermal growth factor receptor-dependent maintenance of cardiac contractility.Cardiovascular Research2022
35428820The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1.Scientific Reports2022
36446940The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression.Scientific Reports2022
34396980Therapeutic targeting of BAG3: considering its complexity in cancer and heart disease.Journal of Clinical Investigation2021
33883434Effect of Reduction Mammoplasty on Pulmonary Function Tests: A Systematic Review.Annals of Plastic Surgery2021
32956817Novel BAG3 Variants in African American Patients With Cardiomyopathy: Reduced β-Adrenergic Responsiveness in Excitation-Contraction.Journal of Cardiac Failure2020
32374444Antidotal effects of methylene blue against cyanide neurological toxicity: in vivo and in vitro studies.Annals of the New York Academy of Sciences2020
32312983Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy.Cell Death and Disease2020
30932190Evidence for the impact of BAG3 on electrophysiological activity of primary culture of neonatal cardiomyocytes.Journal of Cellular Physiology2019
31575956The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2.Scientific Reports2019
30256393Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes.Journal of Cellular Physiology2019
30590764Methylene Blue Administration During and After Life-Threatening Intoxication by Hydrogen Sulfide: Efficacy Studies in Adult Sheep and Mechanisms of Action.Toxicological Sciences2019
30637731Trpm2 enhances physiological bioenergetics and protects against pathological oxidative cardiac injury: Role of Pyk2 phosphorylation.Journal of Cellular Physiology2019
30631036Lamin B is a target for selective nuclear PQC by BAG3: implication for nuclear envelopathies.Cell Death and Disease2019
31188593Correction to "Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine".Journal of Medicinal Chemistry2019
31173149The Central Role of Protein Kinase C Epsilon in Cyanide Cardiotoxicity and Its Treatment.Toxicological Sciences2019
30907955Antidotal Effects of the Phenothiazine Chromophore Methylene Blue Following Cyanide Intoxication.Toxicological Sciences2019
31070089Current Landscape of Heart Failure Gene Therapy.Journal of the American Heart Association2019
31114002Role of Bcl2-associated Athanogene 3 in Turnover of Gap Junction Protein, Connexin 43, in Neonatal Cardiomyocytes.Scientific Reports2019
31549876Letter by Feldman et al Regarding Article, "Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery".Circulation2019
29323723Haplo-insufficiency of Bcl2-associated athanogene 3 in mice results in progressive left ventricular dysfunction, β-adrenergic insensitivity, and increased apoptosis.Journal of Cellular Physiology2018
28493473Dysregulation of mitochondrial bioenergetics and quality control by HIV-1 Tat in cardiomyocytes.Journal of Cellular Physiology2018
30020827The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation.American Journal of Physiology - Cell Physiology2018
30140897Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals.JAMA Cardiol2018
29938246The Multifunctional Protein BAG3: A Novel Therapeutic Target in Cardiovascular Disease.JACC: Basic to Translational Science2018
29451035Revisiting the physiological effects of methylene blue as a treatment of cyanide intoxication.Clinical Toxicology2018
29603116Methylene Blue Counteracts HS-Induced Cardiac Ion Channel Dysfunction and ATP Reduction.Cardiovascular Toxicology2018
29420146Methylene blue counteracts cyanide cardiotoxicity: cellular mechanisms.Journal of Applied Physiology2018
28262504Mitochondrial Ca Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity.Molecular Cell2017
28819214HIV-1 Nef-induced cardiotoxicity through dysregulation of autophagy.Scientific Reports2017
28790515Transient Receptor Potential-Melastatin Channel Family Member 2: Friend or Foe.Transactions of the American Clinical and Climatological Association2017
28323425Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine.Journal of Medicinal Chemistry2017
28611130Precision Medicine for Heart Failure: Lessons From Oncology.Circulation: Heart Failure2017
29070696Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein-Coupled Receptor Kinase 2 Inhibitors.Molecular Pharmacology2017
27381181Evidence for the Role of BAG3 in Mitochondrial Quality Control in Cardiomyocytes.Journal of Cellular Physiology2017
27589993Vasopressin type 1A receptor deletion enhances cardiac contractility, β-adrenergic receptor sensitivity and acute cardiac injury-induced dysfunction.Clinical Science2016
27184846MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.Cell Rep2016
26796036BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes.Journal of Molecular and Cellular Cardiology2016
27050625Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.Journal of Medicinal Chemistry2016
26962024Methylene blue counteracts H2S toxicity-induced cardiac depression by restoring L-type Ca channel activity.American Journal of Physiology - Regulatory Integrative and Comparative Physiology2016
26729625GRP78 Interacting Partner Bag5 Responds to ER Stress and Protects Cardiomyocytes From ER Stress-Induced Apoptosis.Journal of Cellular Biochemistry2016
27354517β-arrestin-biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction.Proceedings of the National Academy of Sciences of the United States of America2016
26420388TRPM2 protects against tissue damage following oxidative stress and ischaemia-reperfusion.Journal of Physiology2016
27694440Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics.Journal of Biological Chemistry2016
27882354Bcl-2-associated athanogene 3 protects the heart from ischemia/reperfusion injury.JCI insight2016
28164169Adeno-associated Virus Serotype 9 - Driven Expression of BAG3 Improves Left Ventricular Function in Murine Hearts with Left Ventricular Dysfunction Secondary to a Myocardial Infarction.JACC: Basic to Translational Science2016
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Lewis Katz School of Medicine, Temple University
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Johns Hopkins University
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