Skip to Main Content

Author Details

Brian R Bettencourt
Alnylam Pharmaceuticals
1999
33
27
PMIDPaper TitleJournal TitlePublished Year
32811423Spider phylosymbiosis: divergence of widow spider species and their tissues' microbiomes.BMC Evol Biol2020
32811423Spider phylosymbiosis: divergence of widow spider species and their tissues' microbiomes.BMC Evol Biol2020
27432743An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria.J Am Soc Nephrol2017
27432743An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria.J Am Soc Nephrol2017
28129130Clinical Proof of Concept for a Novel Hepatocyte-Targeting GalNAc-siRNA Conjugate.Mol Ther2017
27959715A Highly Durable RNAi Therapeutic Inhibitor of PCSK9.N Engl J Med2017
28129130Clinical Proof of Concept for a Novel Hepatocyte-Targeting GalNAc-siRNA Conjugate.Mol Ther2017
27959715A Highly Durable RNAi Therapeutic Inhibitor of PCSK9.N Engl J Med2017
27033334Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis.Amyloid2016
27033334Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis.Amyloid2016
26453570Serial scanning with technetium pyrophosphate ([99m]Tc-PYP) in advanced ATTR cardiac amyloidosis.J Nucl Cardiol2016
26452996ALN-RSV01 for prevention of bronchiolitis obliterans syndrome after respiratory syncytial virus infection in lung transplant recipients.J Heart Lung Transplant2016
26453570Serial scanning with technetium pyrophosphate ([99m]Tc-PYP) in advanced ATTR cardiac amyloidosis.J Nucl Cardiol2016
26452996ALN-RSV01 for prevention of bronchiolitis obliterans syndrome after respiratory syncytial virus infection in lung transplant recipients.J Heart Lung Transplant2016
26208957Rapid progression of familial amyloidotic polyneuropathy: a multinational natural history study.Neurology2015
26208957Rapid progression of familial amyloidotic polyneuropathy: a multinational natural history study.Neurology2015
26338094Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study.Orphanet J Rare Dis2015
26338094Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study.Orphanet J Rare Dis2015
24094767Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial.Lancet2014
24094767Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial.Lancet2014
25012480Retrospective study of a TTR FAP cohort to modify NIS+7 for therapeutic trials.J Neurol Sci2014
25012480Retrospective study of a TTR FAP cohort to modify NIS+7 for therapeutic trials.J Neurol Sci2014
23223430An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia.Blood2013
23984729Safety and efficacy of RNAi therapy for transthyretin amyloidosis.N Engl J Med2013
23223430An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia.Blood2013
23172735Evaluation of exogenous siRNA addition as a metabolic engineering tool for modifying biopharmaceuticals.Biotechnol Prog2013
23984729Safety and efficacy of RNAi therapy for transthyretin amyloidosis.N Engl J Med2013
23172735Evaluation of exogenous siRNA addition as a metabolic engineering tool for modifying biopharmaceuticals.Biotechnol Prog2013
21426536Organization and evolution of hsp70 clusters strikingly differ in two species of Stratiomyidae (Diptera) inhabiting thermally contrasting environments.BMC Evol Biol2011
21426536Organization and evolution of hsp70 clusters strikingly differ in two species of Stratiomyidae (Diptera) inhabiting thermally contrasting environments.BMC Evol Biol2011
20731861In vivo quantification of formulated and chemically modified small interfering RNA by heating-in-Triton quantitative reverse transcription polymerase chain reaction (HIT qRT-PCR).Silence2010
21253006Natural variation of the amino-terminal glutamine-rich domain in Drosophila argonaute2 is not associated with developmental defects.PLoS One2010
20731861In vivo quantification of formulated and chemically modified small interfering RNA by heating-in-Triton quantitative reverse transcription polymerase chain reaction (HIT qRT-PCR).Silence2010
21253006Natural variation of the amino-terminal glutamine-rich domain in Drosophila argonaute2 is not associated with developmental defects.PLoS One2010
19242787Natural variation in Drosophila stressed locomotion meets or exceeds variation caused by hsp70 mutation: analysis of behavior and performance.Behav Genet2009
19242787Natural variation in Drosophila stressed locomotion meets or exceeds variation caused by hsp70 mutation: analysis of behavior and performance.Behav Genet2009
19333534Duplicate gene evolution toward multiple fates at the Drosophila melanogaster HIP/HIP-Replacement locus.J Mol Evol2009
19333534Duplicate gene evolution toward multiple fates at the Drosophila melanogaster HIP/HIP-Replacement locus.J Mol Evol2009
18211703Inducible and constitutive heat shock gene expression responds to modification of Hsp70 copy number in Drosophila melanogaster but does not compensate for loss of thermotolerance in Hsp70 null flies.BMC Biol2008
18211703Inducible and constitutive heat shock gene expression responds to modification of Hsp70 copy number in Drosophila melanogaster but does not compensate for loss of thermotolerance in Hsp70 null flies.BMC Biol2008
17536173Polyglutamine expansion in Drosophila: thermal stress and Hsp70 as selective agents.J Biosci2007
17536173Polyglutamine expansion in Drosophila: thermal stress and Hsp70 as selective agents.J Biosci2007
15746013Evolution of proteins and gene expression levels are coupled in Drosophila and are independently associated with mRNA abundance, protein length, and number of protein-protein interactions.Mol Biol Evol2005
15746013Evolution of proteins and gene expression levels are coupled in Drosophila and are independently associated with mRNA abundance, protein length, and number of protein-protein interactions.Mol Biol Evol2005
15632085Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution.Genome Res2005
15632085Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution.Genome Res2005
15498973Compensated deleterious mutations in insect genomes.Science2004
15498973Compensated deleterious mutations in insect genomes.Science2004
12519916Modification of heat-shock gene expression in Drosophila melanogaster populations via transposable elements.Mol Biol Evol2003
12519916Modification of heat-shock gene expression in Drosophila melanogaster populations via transposable elements.Mol Biol Evol2003
  • 1 - 50 of 66

Recommended Authors

LIFT-Life Improvement by Future Technologies Institute
Career Start Year 2014
Number of shared co-authors 1
Baylor College of Medicine
Career Start Year 2012
Number of shared co-authors 8
1250 S. Collegeville Rd., Collegeville
Career Start Year 2010
Number of shared co-authors 1
Baylor College of Medicine
Career Start Year 2008
Number of shared co-authors 12
Baylor College of Medicine
Career Start Year 2006
Number of shared co-authors 18
Fondazione IRCCS Policlinico San Matteo, University of Pavia
Career Start Year 2005
Number of shared co-authors 0
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
Career Start Year 2005
Number of shared co-authors 0
University of Zurich
Career Start Year 2002
Number of shared co-authors 14
Chinese Academy of Sciences
Career Start Year 2002
Number of shared co-authors 5
Harvard University
Career Start Year 2002
Number of shared co-authors 9
University of Georgia
Career Start Year 2000
Number of shared co-authors 16
University of Missouri
Career Start Year 1999
Number of shared co-authors 9
University of North Carolina at Chapel Hill
Career Start Year 1998
Number of shared co-authors 7
University of Washington
Career Start Year 1997
Number of shared co-authors 0
University of Birmingham
Career Start Year 1996
Number of shared co-authors 6
Purdue University
Career Start Year 1996
Number of shared co-authors 0
University of Notre Dame
Career Start Year 1995
Number of shared co-authors 3
University of California berkeley
Career Start Year 1994
Number of shared co-authors 24
Stanford University
Career Start Year 1991
Number of shared co-authors 0
University of Florida
Career Start Year 1990
Number of shared co-authors 4
Albert Einstein College of Medicine
Career Start Year 1990
Number of shared co-authors 0
Xi'an Jiaotong-Liverpool University
Career Start Year 1988
Number of shared co-authors 12
University of Wisconsin-Madison
Career Start Year 1988
Number of shared co-authors 16
Howard Hughes Medical Institute, University of California Berkeley
Career Start Year 1988
Number of shared co-authors 18
North Carolina State University
Career Start Year 1985
Number of shared co-authors 1
University Hospital Wishaw
Career Start Year 1984
Number of shared co-authors 8
Max Planck Institute for Evolutionary Biology
Career Start Year 1983
Number of shared co-authors 11
Whitehead Institute for Biomedical Research
Career Start Year 1980
Number of shared co-authors 1
The Australian National University
Career Start Year 1975
Number of shared co-authors 12
Georgia Institute of Technology
Career Start Year 1974
Number of shared co-authors 0

Collaborators

Co-authored papers 6
Co-authored papers 5
Harvard University
Co-authored papers 2
The First Affiliated Hospital, Hengyang Medical School, University of South China
Co-authored papers 2
Harvard University
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
University of California Los Angeles
Co-authored papers 2
Co-authored papers 2
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Co-authored papers 1
Wellcome Sanger Institute
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
University of California berkeley
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Lawrence Berkeley National Laboratory
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Lawrence Berkeley National Laboratory
Co-authored papers 1