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Author Details
Full Name
Julia E Maxson
Affiliation
Knight Cancer Institute, Oregon Health & Science University
ORCID
Career Start Year
2009
Papers
44
H Index
20
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36526735
Asxl1 deletion disrupts MYC and RNA polymerase II function in granulocyte progenitors.
Leukemia
2023
37116708
Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity.
J Biol Chem
2023
36976323
Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia.
Mol Cancer Res
2023
36579444
A novel colony stimulating factor 3 receptor activating mutation identified in a patient with chronic neutrophilic leukemia.
Haematologica
2023
36894620
RUNX1::ETO translocations must precede CSF3R mutations to promote acute myeloid leukemia development.
Leukemia
2023
35200567
Co-Occurring CSF3R W791* Germline and Somatic T618I Driver Mutations Induce Early CNL and Clonal Progression to Mixed Phenotype Acute Leukemia.
Curr Oncol
2022
35710794
Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia.
Nat Commun
2022
35794242
Correction: Mutant SETBP1 enhances NRAS-driven MAPK pathway activation to promote aggressive leukemia.
Leukemia
2022
35788238
GoPeaks: histone modification peak calling for CUT&Tag.
Genome Biol
2022
35590033
PU.1 and MYC transcriptional network defines synergistic drug responses to KIT and LSD1 inhibition in acute myeloid leukemia.
Leukemia
2022
35868306
Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.
Cancer Cell
2022
34002029
Mutant SETBP1 enhances NRAS-driven MAPK pathway activation to promote aggressive leukemia.
Leukemia
2021
33830192
A new role for hematoxylin: targeting CALR.
Blood
2021
33516272
Outgrowth of a CSF3R-mutant clone drives a second myeloproliferative neoplasm in a chronic myeloid leukemia patient: a case report.
Biomark Res
2021
34504101
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.
Nat Commun
2021
32471953
Combined inhibition of JAK/STAT pathway and lysine-specific demethylase 1 as a therapeutic strategy in CSF3R/CEBPA mutant acute myeloid leukemia.
Proc Natl Acad Sci U S A
2020
31844143
Insights on mechanisms of clonal evolution in chronic neutrophilic leukemia on ruxolitinib therapy.
Leukemia
2020
31880950
Efficacy of Ruxolitinib in Patients With Chronic Neutrophilic Leukemia and Atypical Chronic Myeloid Leukemia.
J Clin Oncol
2020
32187354
Prognostic impact of CSF3R mutations in favorable risk childhood acute myeloid leukemia.
Blood
2020
31366621
Genomic landscape of neutrophilic leukemias of ambiguous diagnosis.
Blood
2019
31784538
Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia.
Nat Commun
2019
29572350
Gain-of-function mutations in granulocyte colony-stimulating factor receptor (CSF3R) reveal distinct mechanisms of CSF3R activation.
J Biol Chem
2018
30018082
Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia.
Sci Signal
2018
30348809
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia.
Cancer Res
2018
28028025
Genomics of chronic neutrophilic leukemia.
Blood
2017
28630439
Recurrent cyclin D2 mutations in myeloid neoplasms.
Leukemia
2017
27072365
Neogenin Facilitates the Induction of Hepcidin Expression by Hemojuvelin in the Liver.
J Biol Chem
2016
26475333
The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.
Clin Cancer Res
2016
26677978
Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis.
Cancer Res
2016
26389776
Clonality of neutrophilia associated with plasma cell neoplasms: report of a SETBP1 mutation and analysis of a single institution series.
Leuk Lymphoma
2016
27143256
CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML.
Blood
2016
26032424
Therapeutically Targetable ALK Mutations in Leukemia.
Cancer Res
2015
24403076
Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and increased receptor dimerization.
J Biol Chem
2014
25628989
Acute promyelocytic leukemia with JAK2 V617F and severe differentiation syndrome.
Leuk Res Rep
2014
25180155
Significant clinical response to JAK1/2 inhibition in a patient with CSF3R-T618I-positive atypical chronic myeloid leukemia.
Leuk Res Rep
2014
23733748
Cancer- and endotoxin-induced cachexia require intact glucocorticoid signaling in skeletal muscle.
FASEB J
2013
24081659
The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition.
Blood
2013
23896413
The new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatment.
Blood
2013
23604229
CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia.
Leukemia
2013
23656643
Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML.
N Engl J Med
2013
23031643
Expression of myeloid differentiation factor 88 in neurons is not requisite for the induction of sickness behavior by interleukin-1β.
J Neuroinflammation
2012
20122714
The cell giveth and the cell taketh away: an overview of Notch pathway activation by endocytic trafficking of ligands and receptors.
Acta Histochem
2011
20937842
Matriptase-2- and proprotein convertase-cleaved forms of hemojuvelin have different roles in the down-regulation of hepcidin expression.
J Biol Chem
2010
19029439
Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells.
Blood
2009
1 - 44 of 44
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