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Author Details

Nathaniel Huebsch
Washington University in St. Louis
2005
51
28
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37200617Hydrogel-Assisted Double Molding Enables Rapid Replication of Stereolithographic 3D Prints for Engineered Tissue Design.ACS Appl Mater Interfaces2023
37008887Dynamic mechanobiology of cardiac cells and tissues: Current status and future perspective.Biophys Rev (Melville)2023
34886677Pulsus Alternans in Cardiogenic Shock Recapitulated in Single Cell Fluorescence Imaging of a Patient's Cardiomyocyte.Circ Heart Fail2022
35478228Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips.Nat Biomed Eng2022
35618902iPSC-Derived Micro-Heart Muscle for Medium-Throughput Pharmacology and Pharmacogenomic Studies.Methods Mol Biol2022
36272406Collective organization from cellular disorder.Biophys J2022
35925789Robust, Automated Analysis of Electrophysiology in Induced Pluripotent Stem Cell-Derived Micro-Heart Muscle for Drug Toxicity.Tissue Eng Part C Methods2022
35983280Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System.ACS Pharmacol Transl Sci2022
34025426Integrated Isogenic Human Induced Pluripotent Stem Cell-Based Liver and Heart Microphysiological Systems Predict Unsafe Drug-Drug Interaction.Front Pharmacol2021
35014476Copper-Free Azide-Alkyne Cycloaddition for Peptide Modification of Alginate Hydrogels.ACS Appl Bio Mater2021
34492582Integrin and syndecan binding peptide-conjugated alginate hydrogel for modulation of nucleus pulposus cell phenotype.Biomaterials2021
34777601Interplay of Genotype and Substrate Stiffness in Driving the Hypertrophic Cardiomyopathy Phenotype in iPSC-Micro-Heart Muscle Arrays.Cell Mol Bioeng2021
34449624Biocompatible and Enzymatically Degradable Gels for 3D Cellular Encapsulation under Extreme Compressive Strain.Gels2021
34275296Elastomer-Grafted iPSC-Derived Micro Heart Muscles to Investigate Effects of Mechanical Loading on Physiology.ACS Biomater Sci Eng2021
31030627Engineering Tissues from Induced Pluripotent Stem Cells.Tissue Eng Part A2019
31129361Translational mechanobiology: Designing synthetic hydrogel matrices for improved in vitro models and cell-based therapies.Acta Biomater2019
30735344New Molecular Scaffolds for Fluorescent Voltage Indicators.ACS Chem Biol2019
29663322Quantitatively characterizing drug-induced arrhythmic contractile motions of human stem cell-derived cardiomyocytes.Biotechnol Bioeng2018
31015724Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload.Nat Biomed Eng2018
30514966Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems.Sci Rep2018
28739546In-situ tissue regeneration through SDF-1α driven cell recruitment and stiffness-mediated bone regeneration in a critical-sized segmental femoral defect.Acta Biomater2017
28724793A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.JCI Insight2017
26971820CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.Cell Stem Cell2016
26618884Hydrogels with tunable stress relaxation regulate stem cell fate and activity.Nat Mater2016
27095412Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses.Sci Rep2016
25333967Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales.Tissue Eng Part C Methods2015
26366848Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation.Nat Mater2015
26172574Self-organizing human cardiac microchambers mediated by geometric confinement.Nat Commun2015
25695512Substrate stress relaxation regulates cell spreading.Nat Commun2015
25748532Human iPSC-based cardiac microphysiological system for drug screening applications.Sci Rep2015
22689452Characterization of a composite injury model of severe lower limb bone and nerve trauma.J Tissue Eng Regen Med2014
24961369Ultrasound-triggered disruption and self-healing of reversibly cross-linked hydrogels for drug delivery and enhanced chemotherapy.Proc Natl Acad Sci U S A2014
24268663Three-dimensional filamentous human diseased cardiac tissue model.Biomaterials2014
22992043Attenuated human bone morphogenetic protein-2-mediated bone regeneration in a rat model of composite bone and muscle injury.Tissue Eng Part C Methods2013
23664918Recovery from hind limb ischemia enhances rhBMP-2-mediated segmental bone defect repair in a rat composite injury model.Bone2013
22011105Adipose tissue engineering using injectable, oxidized alginate hydrogels.Tissue Eng Part A2012
20864165An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects.Biomaterials2011
21876139Mechanical regulation of vascular growth and tissue regeneration in vivo.Proc Natl Acad Sci U S A2011
21621027Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects.Bone2011
21299954[Cell-traction mediated configuration of the cell/extracellular-matrix interface plays a key role in stem cell fate].Med Sci (Paris)2011
21149682Active scaffolds for on-demand drug and cell delivery.Proc Natl Acad Sci U S A2011
19830565Patterning alginate hydrogels using light-directed release of caged calcium in a microfluidic device.Biomed Microdevices2010
21464912Stress-relaxation behavior in gels with ionic and covalent crosslinks.J Appl Phys2010
20418863Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate.Nat Mater2010
18783323Cyclic arginine-glycine-aspartate peptides enhance three-dimensional stem cell osteogenic differentiation.Tissue Eng Part A2009
19940912Inspiration and application in the evolution of biomaterials.Nature2009
19136947Infection-mimicking materials to program dendritic cells in situ.Nat Mater2009
18540674Integrin-adhesion ligand bond formation of preosteoblasts and stem cells in three-dimensional RGD presenting matrices.Biomacromolecules2008
17270268Fluorescent resonance energy transfer: A tool for probing molecular cell-biomaterial interactions in three dimensions.Biomaterials2007
17381090Noninvasive probing of the spatial organization of polymer chains in hydrogels using fluorescence resonance energy transfer (FRET).J Am Chem Soc2007
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Collaborators

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Co-authored papers 9
University of Pennsylvania School of Medicine
Co-authored papers 6
Gladstone Institute of Cardiovascular Disease
Co-authored papers 6
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Co-authored papers 4
Gladstone Institutes
Co-authored papers 4
University of California San Francisco Department of Psychiatry
Co-authored papers 3
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Co-authored papers 3
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Co-authored papers 3
Gladstone Institutes San Francisco
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Broad Institute of MIT and Harvard
Co-authored papers 1
Emory University
Co-authored papers 1
Arc Institute
Co-authored papers 1
Gladstone Institute of Cardiovascular Disease
Co-authored papers 1
J. David Gladstone Institutes
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Tokyo Metropolitan Institute of Medical Science, Japan Gladstone Institutes
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Odense University Hospital
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Harvard University
Co-authored papers 1
Odense University Hospital, University of Southern Denmark
Co-authored papers 1
Gladstone Institutes
Co-authored papers 1
Center for Drug Evaluation and Research
Co-authored papers 1
Gladstone Institute of Cardiovascular Disease
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Gladstone Institutes
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University of California santa barbara
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Stanford University
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