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Author Details
Full Name
Nathaniel Huebsch
Affiliation
Washington University in St. Louis
ORCID
Career Start Year
2005
Papers
51
H Index
28
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37200617
Hydrogel-Assisted Double Molding Enables Rapid Replication of Stereolithographic 3D Prints for Engineered Tissue Design.
ACS Appl Mater Interfaces
2023
37008887
Dynamic mechanobiology of cardiac cells and tissues: Current status and future perspective.
Biophys Rev (Melville)
2023
34886677
Pulsus Alternans in Cardiogenic Shock Recapitulated in Single Cell Fluorescence Imaging of a Patient's Cardiomyocyte.
Circ Heart Fail
2022
35478228
Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips.
Nat Biomed Eng
2022
35618902
iPSC-Derived Micro-Heart Muscle for Medium-Throughput Pharmacology and Pharmacogenomic Studies.
Methods Mol Biol
2022
36272406
Collective organization from cellular disorder.
Biophys J
2022
35925789
Robust, Automated Analysis of Electrophysiology in Induced Pluripotent Stem Cell-Derived Micro-Heart Muscle for Drug Toxicity.
Tissue Eng Part C Methods
2022
35983280
Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System.
ACS Pharmacol Transl Sci
2022
34025426
Integrated Isogenic Human Induced Pluripotent Stem Cell-Based Liver and Heart Microphysiological Systems Predict Unsafe Drug-Drug Interaction.
Front Pharmacol
2021
35014476
Copper-Free Azide-Alkyne Cycloaddition for Peptide Modification of Alginate Hydrogels.
ACS Appl Bio Mater
2021
34492582
Integrin and syndecan binding peptide-conjugated alginate hydrogel for modulation of nucleus pulposus cell phenotype.
Biomaterials
2021
34777601
Interplay of Genotype and Substrate Stiffness in Driving the Hypertrophic Cardiomyopathy Phenotype in iPSC-Micro-Heart Muscle Arrays.
Cell Mol Bioeng
2021
34449624
Biocompatible and Enzymatically Degradable Gels for 3D Cellular Encapsulation under Extreme Compressive Strain.
Gels
2021
34275296
Elastomer-Grafted iPSC-Derived Micro Heart Muscles to Investigate Effects of Mechanical Loading on Physiology.
ACS Biomater Sci Eng
2021
31030627
Engineering Tissues from Induced Pluripotent Stem Cells.
Tissue Eng Part A
2019
31129361
Translational mechanobiology: Designing synthetic hydrogel matrices for improved in vitro models and cell-based therapies.
Acta Biomater
2019
30735344
New Molecular Scaffolds for Fluorescent Voltage Indicators.
ACS Chem Biol
2019
29663322
Quantitatively characterizing drug-induced arrhythmic contractile motions of human stem cell-derived cardiomyocytes.
Biotechnol Bioeng
2018
31015724
Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload.
Nat Biomed Eng
2018
30514966
Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems.
Sci Rep
2018
28739546
In-situ tissue regeneration through SDF-1α driven cell recruitment and stiffness-mediated bone regeneration in a critical-sized segmental femoral defect.
Acta Biomater
2017
28724793
A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.
JCI Insight
2017
26971820
CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.
Cell Stem Cell
2016
26618884
Hydrogels with tunable stress relaxation regulate stem cell fate and activity.
Nat Mater
2016
27095412
Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses.
Sci Rep
2016
25333967
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales.
Tissue Eng Part C Methods
2015
26366848
Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation.
Nat Mater
2015
26172574
Self-organizing human cardiac microchambers mediated by geometric confinement.
Nat Commun
2015
25695512
Substrate stress relaxation regulates cell spreading.
Nat Commun
2015
25748532
Human iPSC-based cardiac microphysiological system for drug screening applications.
Sci Rep
2015
22689452
Characterization of a composite injury model of severe lower limb bone and nerve trauma.
J Tissue Eng Regen Med
2014
24961369
Ultrasound-triggered disruption and self-healing of reversibly cross-linked hydrogels for drug delivery and enhanced chemotherapy.
Proc Natl Acad Sci U S A
2014
24268663
Three-dimensional filamentous human diseased cardiac tissue model.
Biomaterials
2014
22992043
Attenuated human bone morphogenetic protein-2-mediated bone regeneration in a rat model of composite bone and muscle injury.
Tissue Eng Part C Methods
2013
23664918
Recovery from hind limb ischemia enhances rhBMP-2-mediated segmental bone defect repair in a rat composite injury model.
Bone
2013
22011105
Adipose tissue engineering using injectable, oxidized alginate hydrogels.
Tissue Eng Part A
2012
20864165
An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects.
Biomaterials
2011
21876139
Mechanical regulation of vascular growth and tissue regeneration in vivo.
Proc Natl Acad Sci U S A
2011
21621027
Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects.
Bone
2011
21299954
[Cell-traction mediated configuration of the cell/extracellular-matrix interface plays a key role in stem cell fate].
Med Sci (Paris)
2011
21149682
Active scaffolds for on-demand drug and cell delivery.
Proc Natl Acad Sci U S A
2011
19830565
Patterning alginate hydrogels using light-directed release of caged calcium in a microfluidic device.
Biomed Microdevices
2010
21464912
Stress-relaxation behavior in gels with ionic and covalent crosslinks.
J Appl Phys
2010
20418863
Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate.
Nat Mater
2010
18783323
Cyclic arginine-glycine-aspartate peptides enhance three-dimensional stem cell osteogenic differentiation.
Tissue Eng Part A
2009
19940912
Inspiration and application in the evolution of biomaterials.
Nature
2009
19136947
Infection-mimicking materials to program dendritic cells in situ.
Nat Mater
2009
18540674
Integrin-adhesion ligand bond formation of preosteoblasts and stem cells in three-dimensional RGD presenting matrices.
Biomacromolecules
2008
17270268
Fluorescent resonance energy transfer: A tool for probing molecular cell-biomaterial interactions in three dimensions.
Biomaterials
2007
17381090
Noninvasive probing of the spatial organization of polymer chains in hydrogels using fluorescence resonance energy transfer (FRET).
J Am Chem Soc
2007
1 - 50 of 51
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