Author details

Full Name

Benjamin K Chen

Affiliation

ORCID

Career Start Year

1994

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37352211	Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design.	PLoS One	2023
37140960	Viral persistence, reactivation, and mechanisms of long COVID.		2023
37450338	Viral persistence in the Gut-Associated Lymphoid Tissue and barriers to HIV cure.		2023
35323042	The HIV Env Glycoprotein Conformational States on Cells and Viruses.	mBio	2022
34986207	Non-neutralizing antibodies targeting the immunogenic regions of HIV-1 envelope reduce mucosal infection and virus burden in humanized mice.	PLoS Pathogens	2022
34578310	Endocytic Motif on a Biotin-Tagged HIV-1 Env Modulates the Co-Transfer of Env and Gag during Cell-to-Cell Transmission.	Viruses	2021
35062242	A Replication-Competent HIV Clone Carrying GFP-Env Reveals Rapid Env Recycling at the HIV-1 T Cell Virological Synapse.	Viruses	2021
32701578	Proliferation of HIV-infected renal epithelial cells following virus acquisition from infected macrophages.	AIDS	2020
31852781	P2X1 Selective Antagonists Block HIV-1 Infection through Inhibition of Envelope Conformation-Dependent Fusion.	Journal of Virology	2020
32934372	Convalescent plasma treatment of severe COVID-19: a propensity score-matched control study.	Nat Med	2020
30646921	Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging.	Retrovirology	2019
31557312	Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic coculture.	FEBS Lett	2019
30415130	Variable infectivity and conserved engagement in cell-to-cell viral transfer by HIV-1 Env from Clade B transmitted founder clones.	Virology	2019
30176017	A High-throughput Cre-Lox Activated Viral Membrane Fusion Assay to Identify Inhibitors of HIV-1 Viral Membrane Fusion.	Journal of Visualized Experiments	2018
30305360	P2X Antagonists Inhibit HIV-1 Productive Infection and Inflammatory Cytokines Interleukin-10 (IL-10) and IL-1Î² in a Human Tonsil Explant Model.	J Virol	2018
30282696	Anti-Î±4Î²7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1-infected individuals.	Sci Transl Med	2018
30517869	Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming.	Cell Rep	2018
28148796	Reduced Potency and Incomplete Neutralization of Broadly Neutralizing Antibodies against Cell-to-Cell Transmission of HIV-1 with Transmitted Founder Envs.	Journal of Virology	2017
28239647	Enhanced FCGR2A and FCGR3A signaling by HIV viremic controller IgG.	JCI Insight	2017
27847357	Visualization of HIV T Cell Virological Synapses and Virus-Containing Compartments by Three-Dimensional Correlative Light and Electron Microscopy.	J Virol	2017
27600154	The HIV-1 late domain-2 S40A polymorphism in antiretroviral (or ART)-exposed individuals influences protease inhibitor susceptibility.	Retrovirology	2016
27112280	Cell-to-Cell Spread of HIV and Viral Pathogenesis.	Advances in Virus Research	2016
26803470	A high throughput Cre-lox activated viral membrane fusion assay identifies pharmacological inhibitors of HIV entry.	Virology	2016
27292632	InÂ Vivo HIV-1 Cell-to-Cell Transmission Promotes Multicopy Micro-compartmentalized Infection.	Cell Reports	2016
27163710	HIV infection-induced transcriptional program in renal tubular epithelial cells activates a CXCR2-driven CD4+ T-cell chemotactic response.	AIDS	2016
26714702	Measuring T Cell-to-T Cell HIV-1 Transfer, Viral Fusion, and Infection Using Flow Cytometry.	Methods in Molecular Biology	2016
26635799	Purinergic Receptors: Key Mediators of HIV-1 Infection and Inflammation.	Frontiers in Immunology	2015
25669151	Phenotype and function of nasal dendritic cells.	Mucosal Immunology	2015
26136566	HIV-1 Cell-Free and Cell-to-Cell Infections Are Differentially Regulated by Distinct Determinants in the Env gp41 Cytoplasmic Tail.	Journal of Virology	2015
26387945	IFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein.	Cell Reports	2015
25062092	Renal epithelial cells produce and spread HIV-1 via T-cell contact.	AIDS	2014
25522148	Unique features of HIV-1 spread through T cell virological synapses.	PLoS Pathogens	2014
25031337	P2X-selective purinergic antagonists are strong inhibitors of HIV-1 fusion during both cell-to-cell and cell-free infection.	J Virol	2014
24623433	HIV-1 Vpu antagonism of tetherin inhibits antibody-dependent cellular cytotoxic responses by natural killer cells.	J Virol	2014
24648457	HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes.	J Virol	2014
23278744	Mechanisms of enhanced HIV spread through T-cell virological synapses.	Immunological Reviews	2013
23908485	Postintegration HIV-1 infection of cervical epithelial cells mediates contact-dependent productive infection of T cells.	Journal of Infectious Diseases	2013
22448282	Cannabinoid receptor 2-mediated attenuation of CXCR4-tropic HIV infection in primary CD4+ T cells.	PLoS ONE	2012
22553332	Neutralization resistance of virological synapse-mediated HIV-1 Infection is regulated by the gp41 cytoplasmic tail.	Journal of Virology	2012
22477441	T cell virological synapses and HIV-1 pathogenesis.	Immunologic Research	2012
21543479	Multiploid inheritance of HIV-1 during cell-to-cell infection.	Journal of Virology	2011
21335514	Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells.	Journal of the American Society of Nephrology : JASN	2011
20627127	Tracking and quantitation of fluorescent HIV during cell-to-cell transmission.	Methods	2011
22177560	Cell-to-cell transfer of HIV-1 via virological synapses leads to endosomal virion maturation that activates viral membrane fusion.		2011
20301121	Manipulating CD4+ T cells by optical tweezers for the initiation of cell-cell transfer of HIV-1.		2010
20683959	Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis.	Hepatology	2010
20972408	Visualizing cell-to-cell transfer of HIV using fluorescent clones of HIV and live confocal microscopy.	Journal of Visualized Experiments	2010
19325119	Quantitative 3D video microscopy of HIV transfer across T cell virological synapses.	Science	2009
17728233	Sequence of human immunodeficiency virus type 1 (HIV-1) Gag localization and oligomerization monitored with live confocal imaging of a replication-competent, fluorescently tagged HIV-1.	Journal of Virology	2007
17360402	Lymphotoxin beta receptor signaling is required for inflammatory lymphangiogenesis in the thyroid.	Proc Natl Acad Sci U S A	2007