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Author Details

Marcelo F Lopez
Charleston Alcohol Research Center, Medical University of South Carolina
1996
78
31
PMIDPaper TitleJournal TitlePublished Year
36328184Alcohol dependence and the ventral hippocampal influence on alcohol drinking in male mice.Alcohol2023
36656645Preclinical and clinical evidence for suppression of alcohol intake by apremilast.J Clin Invest2023
36709008Agmatine reduces alcohol drinking and produces antinociceptive effects in rodent models of alcohol use disorder.Alcohol2023
36736419Alcohol Dependence Modifies Brain Networks Activated During Withdrawal and Reaccess: A c-Fos-Based Analysis in Mice.Biol Psychiatry2023
36822933Oxytocin Reduces Sensitized Stress-Induced Alcohol Relapse in a Model of Posttraumatic Stress Disorder and Alcohol Use Disorder Comorbidity.Biol Psychiatry2023
36792030Chronic intermittent ethanol exposure differentially alters the excitability of neurons in the orbitofrontal cortex and basolateral amygdala that project to the dorsal striatum.Neuropharmacology2023
34013595The histone methyltransferase G9a mediates stress-regulated alcohol drinking.Addict Biol2022
36055466Effect of chronic intermittent ethanol vapor exposure on RNA content of brain-derived extracellular vesicles.Alcohol2022
35190188Dynorphin/Kappa Opioid Receptor Activity Within the Extended Amygdala Contributes to Stress-Enhanced Alcohol Drinking in Mice.Biol Psychiatry2022
35181404Assessing negative affect in mice during abstinence from alcohol drinking: Limitations and future challenges.Alcohol2022
33181147Interaction of chronic intermittent ethanol and repeated stress on structural and functional plasticity in the mouse medial prefrontal cortex.Neuropharmacology2021
34127796Activation of hypothalamic oxytocin neurons reduces binge-like alcohol drinking through signaling at central oxytocin receptors.Neuropsychopharmacology2021
33052417The escalation in ethanol consumption following chronic intermittent ethanol exposure is blunted in mice expressing ethanol-resistant GluN1 or GluN2A NMDA receptor subunits.Psychopharmacology (Berl)2021
30468275Sex-dependent differences in ethanol inhibition of mouse lateral orbitofrontal cortex neurons.Addict Biol2020
32023486Kappa opioid receptors in the bed nucleus of the stria terminalis regulate binge-like alcohol consumption in male and female mice.Neuropharmacology2020
33247097Bioinformatics identification and pharmacological validation of Kcnn3/K<sub>Ca</sub>2 channels as a mediator of negative affective behaviors and excessive alcohol drinking in mice.Transl Psychiatry2020
32712186Evaluation of the effect of doxasozin and zonisamide on voluntary ethanol intake in mice that experienced chronic intermittent ethanol exposure and stress.Alcohol2020
32469986Brain regional gene expression network analysis identifies unique interactions between chronic ethanol exposure and consumption.PLoS One2020
31288295Dynamic c-Fos changes in mouse brain during acute and protracted withdrawal from chronic intermittent ethanol exposure and relapse drinking.Addict Biol2020
30555162Dynorphin-kappa opioid receptor activity in the central amygdala modulates binge-like alcohol drinking in mice.Neuropsychopharmacology2019
31211793Correction: Time-Course Analysis of Brain Regional Expression Network Responses to Chronic Intermittent Ethanol and Withdrawal: Implications for Mechanisms Underlying Excessive Ethanol Consumption.PLoS One2019
31456662Cross-Species Co-analysis of Prefrontal Cortex Chronic Ethanol Transcriptome Responses in Mice and Monkeys.Front Mol Neurosci2019
31068843Early Blood Profile of C57BL/6 Mice Exposed to Chronic Unpredictable Stress.Front Psychiatry2019
30790666Brain Regional and Temporal Changes in BDNF mRNA and microRNA-206 Expression in Mice Exposed to Repeated Cycles of Chronic Intermittent Ethanol and Forced Swim Stress.Neuroscience2019
29315347Long-term ethanol exposure: Temporal pattern of microRNA expression and associated mRNA gene networks in mouse brain.PLoS One2018
30213503Cross-species molecular dissection across alcohol behavioral domains.Alcohol2018
30056122Increasing Brain-Derived Neurotrophic Factor (BDNF) in medial prefrontal cortex selectively reduces excessive drinking in ethanol dependent mice.Neuropharmacology2018
29689260Effects of monoamines on the intrinsic excitability of lateral orbitofrontal cortex neurons in alcohol-dependent and non-dependent female mice.Neuropharmacology2018
27432260Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking.Alcohol2017
28139680Ethanol Dependence Abolishes Monoamine and GIRK (Kir3) Channel Inhibition of Orbitofrontal Cortex Excitability.Neuropsychopharmacology2017
28890345Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward.Neuron2017
27793543Variable effects of chronic intermittent ethanol exposure on ethanol drinking in a genetically diverse mouse cohort.Alcohol2017
27838001The allostatic impact of chronic ethanol on gene expression: A genetic analysis of chronic intermittent ethanol treatment in the BXD cohort.Alcohol2017
27894806Genetic divergence in the transcriptional engram of chronic alcohol abuse: A laser-capture RNA-seq study of the mouse mesocorticolimbic system.Alcohol2017
27884493Initial genetic dissection of serum neuroactive steroids following chronic intermittent ethanol across BXD mouse strains.Alcohol2017
27425261Dopamine synthesis in alcohol drinking-prone and -resistant mouse strains.Alcohol2017
26730594Time-Course Analysis of Brain Regional Expression Network Responses to Chronic Intermittent Ethanol and Withdrawal: Implications for Mechanisms Underlying Excessive Ethanol Consumption.PLoS One2016
26625893Supersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens.Int J Neuropsychopharmacol2016
26286839Chronic Intermittent Ethanol Exposure Enhances the Excitability and Synaptic Plasticity of Lateral Orbitofrontal Cortex Neurons and Induces a Tolerance to the Acute Inhibitory Actions of Ethanol.Neuropsychopharmacology2016
26992696Effect of different stressors on voluntary ethanol intake in ethanol-dependent and nondependent C57BL/6J mice.Alcohol2016
26941607Stress-Induced Enhancement of Ethanol Intake in C57BL/6J Mice with a History of Chronic Ethanol Exposure: Involvement of Kappa Opioid Receptors.Front Cell Neurosci2016
26935824Forced swim stress increases ethanol consumption in C57BL/6J mice with a history of chronic intermittent ethanol exposure.Psychopharmacology (Berl)2016
26851547The highly selective orexin/hypocretin 1 receptor antagonist GSK1059865 potently reduces ethanol drinking in ethanol dependent mice.Brain Res2016
27055614An Animal Model of Alcohol Dependence to Screen Medications for Treating Alcoholism.Int Rev Neurobiol2016
24215262Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence.Addict Biol2015
26080318The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence.Transl Psychiatry2015
25662840KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction.Neuropsychopharmacology2015
25803291Chronic ethanol exposure produces time- and brain region-dependent changes in gene coexpression networks.PLoS One2015
25446196Impact of social isolation and enriched environment during adolescence on voluntary ethanol intake and anxiety in C57BL/6J mice.Physiol Behav2015
25468278Withdrawal from chronic intermittent alcohol exposure increases dendritic spine density in the lateral orbitofrontal cortex of mice.Alcohol2015
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Collaborators

Virginia Commonwealth University
Co-authored papers 12
Mayo Clinic
Co-authored papers 8
Oregon National Primate Research Center, Oregon Health and Science University.
Co-authored papers 4
Center for Neuroscience, University of Pittsburgh
Co-authored papers 4
University of Tennessee Health Science Center.
Co-authored papers 3
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin
Co-authored papers 3
University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.
Co-authored papers 2
Center for Systems Neurogenetics of Addiction at The Jackson Laboratory
Co-authored papers 2
University of British Columbia
Co-authored papers 1
Portland Alcohol Research Center, Oregon Health & Science University
Co-authored papers 1
Portland Alcohol Research Center, Oregon Health & Science University
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Portland Alcohol Research Center, Oregon Health and Science University
Co-authored papers 1
Oregon National Primate Research Center, Oregon Health & Science University
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
University of Missouri
Co-authored papers 1
University of California san francisco
Co-authored papers 1
University of Wisconsin
Co-authored papers 1
Oregon National Primate Research Center
Co-authored papers 1
The Scripps Research Institute
Co-authored papers 1
Research Triangle Institute.
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Wake Forest School of Medicine
Co-authored papers 1
University of Tennessee Health Science Center
Co-authored papers 1
Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism.
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Virginia Commonwealth University
Co-authored papers 1
National Institute of Environmental Health Sciences Research Triangle Park
Co-authored papers 1