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Author Details
Full Name
Robert K Campbell
Affiliation
Serono Research Institute
ORCID
Career Start Year
1990
Papers
30
H Index
19
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
25283372
Repurposing human PDE4 inhibitors for neglected tropical diseases. Evaluation of analogs of the human PDE4 inhibitor GSK-256066 as inhibitors of PDEB1 of Trypanosoma brucei.
Chem Biol Drug Des
2015
25283372
Repurposing human PDE4 inhibitors for neglected tropical diseases. Evaluation of analogs of the human PDE4 inhibitor GSK-256066 as inhibitors of PDEB1 of Trypanosoma brucei.
Chem Biol Drug Des
2015
25977593
Evaluation of pyrrolidine and pyrazolone derivatives as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1).
Tetrahedron Lett
2015
25977593
Evaluation of pyrrolidine and pyrazolone derivatives as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1).
Tetrahedron Lett
2015
25127163
Repurposing human PDE4 inhibitors for neglected tropical diseases: design, synthesis and evaluation of cilomilast analogues as Trypanosoma brucei PDEB1 inhibitors.
Bioorg Med Chem Lett
2014
25127163
Repurposing human PDE4 inhibitors for neglected tropical diseases: design, synthesis and evaluation of cilomilast analogues as Trypanosoma brucei PDEB1 inhibitors.
Bioorg Med Chem Lett
2014
24042005
Synthesis and assessment of catechol diether compounds as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1).
Bioorg Med Chem Lett
2013
24042005
Synthesis and assessment of catechol diether compounds as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1).
Bioorg Med Chem Lett
2013
22370268
Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 1. Sildenafil analogs.
Bioorg Med Chem Lett
2012
22377518
Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 2. Tadalafil analogs.
Bioorg Med Chem Lett
2012
22370268
Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 1. Sildenafil analogs.
Bioorg Med Chem Lett
2012
22377518
Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 2. Tadalafil analogs.
Bioorg Med Chem Lett
2012
21859304
Target repurposing for neglected diseases.
Future Med Chem
2011
22023548
Pharmacological validation of Trypanosoma brucei phosphodiesterases B1 and B2 as druggable targets for African sleeping sickness.
J Med Chem
2011
21859304
Target repurposing for neglected diseases.
Future Med Chem
2011
22023548
Pharmacological validation of Trypanosoma brucei phosphodiesterases B1 and B2 as druggable targets for African sleeping sickness.
J Med Chem
2011
18048458
Fine-scale quantification of HCG beta gene transcription in human trophoblastic and non-malignant non-trophoblastic tissues.
Mol Hum Reprod
2008
18048458
Fine-scale quantification of HCG beta gene transcription in human trophoblastic and non-malignant non-trophoblastic tissues.
Mol Hum Reprod
2008
18927591
Genomic-scale prioritization of drug targets: the TDR Targets database.
Nat Rev Drug Discov
2008
18424034
Comparative expression analysis of four breast cancer subtypes versus matched normal tissue from the same patients.
J Steroid Biochem Mol Biol
2008
18927591
Genomic-scale prioritization of drug targets: the TDR Targets database.
Nat Rev Drug Discov
2008
18424034
Comparative expression analysis of four breast cancer subtypes versus matched normal tissue from the same patients.
J Steroid Biochem Mol Biol
2008
17495128
Tumor necrosis factor (TNF)-soluble high-affinity receptor complex as a TNF antagonist.
J Pharmacol Exp Ther
2007
17495128
Tumor necrosis factor (TNF)-soluble high-affinity receptor complex as a TNF antagonist.
J Pharmacol Exp Ther
2007
16210364
Bone morphogenetic protein-15 in the zebrafish ovary: complementary deoxyribonucleic acid cloning, genomic organization, tissue distribution, and role in oocyte maturation.
Endocrinology
2006
16210364
Bone morphogenetic protein-15 in the zebrafish ovary: complementary deoxyribonucleic acid cloning, genomic organization, tissue distribution, and role in oocyte maturation.
Endocrinology
2006
16021632
Main-chain conformational tendencies of amino acids.
Proteins
2005
16034184
Molecular pharmacology of gonadotropins.
Endocrine
2005
16021632
Main-chain conformational tendencies of amino acids.
Proteins
2005
16110093
Myelin tetraspan family proteins but no non-tetraspan family proteins are present in the ascidian (Ciona intestinalis) genome.
Biol Bull
2005
16034184
Molecular pharmacology of gonadotropins.
Endocrine
2005
16110093
Myelin tetraspan family proteins but no non-tetraspan family proteins are present in the ascidian (Ciona intestinalis) genome.
Biol Bull
2005
15262408
Piecing together evolution of the vertebrate endocrine system.
Trends Genet
2004
27690613
Initial Sequence and Protein Modeling Results of a Mitochondrial Genome Project on Understudied Invertebrate Phyla.
Biol Bull
2004
15262408
Piecing together evolution of the vertebrate endocrine system.
Trends Genet
2004
27690613
Initial Sequence and Protein Modeling Results of a Mitochondrial Genome Project on Understudied Invertebrate Phyla.
Biol Bull
2004
11884080
Zebrafish as a model for vertebrate reproduction: characterization of the first functional zebrafish (Danio rerio) gonadotropin receptor.
Gen Comp Endocrinol
2002
11884080
Zebrafish as a model for vertebrate reproduction: characterization of the first functional zebrafish (Danio rerio) gonadotropin receptor.
Gen Comp Endocrinol
2002
12481130
The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins.
Science
2002
12470813
Inferring protein function from genomic sequence: Giardia lamblia expresses a phosphatidylinositol kinase-related kinase similar to yeast and mammalian TOR.
Comp Biochem Physiol B Biochem Mol Biol
2002
12481130
The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins.
Science
2002
12470813
Inferring protein function from genomic sequence: Giardia lamblia expresses a phosphatidylinositol kinase-related kinase similar to yeast and mammalian TOR.
Comp Biochem Physiol B Biochem Mol Biol
2002
11266609
Threading of a glycosylated protein loop through a protein hole: implications for combination of human chorionic gonadotropin subunits.
Protein Sci
2001
11266609
Threading of a glycosylated protein loop through a protein hole: implications for combination of human chorionic gonadotropin subunits.
Protein Sci
2001
9013570
Influence of subunit interactions on lutropin specificity. Implications for studies of glycoprotein hormone function.
J Biol Chem
1997
9013570
Influence of subunit interactions on lutropin specificity. Implications for studies of glycoprotein hormone function.
J Biol Chem
1997
9131622
Chimeric proteins can exceed the sum of their parts: implications for evolution and protein design.
Nat Biotechnol
1997
9131622
Chimeric proteins can exceed the sum of their parts: implications for evolution and protein design.
Nat Biotechnol
1997
7650019
The groove between the alpha- and beta-subunits of hormones with lutropin (LH) activity appears to contact the LH receptor, and its conformation is changed during hormone binding.
J Biol Chem
1995
7650020
Model of human chorionic gonadotropin and lutropin receptor interaction that explains signal transduction of the glycoprotein hormones.
J Biol Chem
1995
1 - 50 of 60
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row(s) 1 - 30 of 30
Collaborators
Maris Laan
Co-authored papers
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Co-authored papers
2
Christophe L M J Verlinde
University of Washington
Co-authored papers
1
Christiane Hertz-Fowler
Institute of Integrative Biology, University of Liverpool
Co-authored papers
1
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University of California San Francisco
Co-authored papers
1
Takashi Suzuki
Co-authored papers
1
Zhiping Weng
University of Massachusetts Medical School
Co-authored papers
1
Wesley C Van Voorhis
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Co-authored papers
1
Mitchell L Sogin
Co-authored papers
1
Dhanasekaran Shanmugam
CSIR - National Chemical Laboratory
Co-authored papers
1
Bissan Al-Lazikani
The University of Texas MD Anderson Cancer Center
Co-authored papers
1
Maria A Doyle
Peter MacCallum Cancer Centre
Co-authored papers
1
Andrew L Hopkins
University of Dundee
Co-authored papers
1
Margherita Branno
Co-authored papers
1
Matthew Berriman
Wellcome Sanger Institute
Co-authored papers
1
Gregg McAllister
Co-authored papers
1
Trevor Hawkins
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1
Santiago J Carmona
AGORA Cancer Research Center
Co-authored papers
1
Ian M Carruthers
College of Life Sciences, University of Dundee
Co-authored papers
1
Feng Chen
Bayer Healthcare Pharmaceuticals
Co-authored papers
1
Stuart A Ralph
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David S Roos
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