Author details

Full Name

Graeme J Stewart

Affiliation

ORCID

Career Start Year

1977

Papers

175

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34163021	Expression of CYP24A1 and other multiple sclerosis risk genes in peripheral blood indicates response to vitamin D in homeostatic and inflammatory conditions.	Genes and Immunity	2021
33037402	Regulation of the methylome in differentiation from adult stem cells may underpin vitamin D risk in MS.	Genes and Immunity	2020
31619767	Transcribed B lymphocyte genes and multiple sclerosis risk genes are underrepresented in Epstein-Barr Virus hypomethylated regions.	Genes and Immunity	2020
31932685	The interaction of Multiple Sclerosis risk loci with Epstein-Barr virus phenotypes implicates the virus in pathogenesis.	Scientific Reports	2020
31039804	Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility.	Genome Medicine	2019
30285234	The latitude-dependent autoimmune disease risk genes ZMIZ1 and IRF8 regulate mononuclear phagocytic cell differentiation in response to vitamin D.	Human Molecular Genetics	2019
29363187	GPR65 inhibits experimental autoimmune encephalomyelitis through CD4<sup>+</sup> T cell independent mechanisms that include effects on iNKT cells.	Immunol Cell Biol	2018
29507931	Association of Regulatory T-Cell Expansion With Progression of Amyotrophic Lateral Sclerosis: A Study of Humans and a Transgenic Mouse Model.	JAMA Neurology	2018
28275670	Data characterizing the ZMIZ1 molecular phenotype of multiple sclerosis.	Data Brief	2017
28063629	The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis.	J Autoimmun	2017
26762769	The low EOMES/TBX21 molecular phenotype in multiple sclerosis reflects CD56+ cell dysregulation and is affected by immunomodulatory therapies.	Clinical Immunology	2016
28607721	Differences in common heritable blood immune cell populations may underlie MS susceptibility and progression.	Multiple Sclerosis Journal - Experimental, Translational and Clinical	2016
26986782	Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases.	Genes Immun	2016
27307212	IFNL3/4 genotype is associated with altered immune cell populations in peripheral blood in chronic hepatitis C infection.	Genes and Immunity	2016
26068105	The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function.	PLoS ONE	2015
25735579	Does the BRAF(V600E) mutation herald a new treatment era for Erdheim-Chester disease? A case-based review of a rare and difficult to diagnose disorder.	Internal Medicine Journal	2015
26343388	Class II HLA interactions modulate genetic risk for multiple sclerosis.	Nat Genet	2015
24495857	The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease.	Clin Immunol	2014
25364774	Antibodies to myelin oligodendrocyte glycoprotein in bilateral and recurrent optic neuritis.	Neurol Neuroimmunol Neuroinflamm	2014
24126065	Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected by season.	Multiple Sclerosis Journal	2014
24045339	IFNL3 mediates interaction between innate immune cells: Implications for hepatitis C virus pathogenesis.	Innate Immunity	2014
24158849	The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells.	Human Molecular Genetics	2014
24335707	Hepatic metallothionein expression in chronic hepatitis C virus infection is IFNL3 genotype-dependent.	Genes Immun	2014
23594959	CCR5-Î¿32 genotype does not improve predictive value of IL28B polymorphisms for treatment response in chronic HCV infection.	Genes and Immunity	2013
24076602	Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.	Nat Genet	2013
24204859	Association of IFNL3 rs12979860 and rs8099917 with biochemical predictors of interferon responsiveness in chronic hepatitis C virus infection.	PLoS ONE	2013
24147013	IL7RÎ± expression and upregulation by IFNÎ² in dendritic cell subsets is haplotype-dependent.	PLoS ONE	2013
23739915	MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis.	Brain	2013
21938017	The role of SNPs in the Î±-chain of the IL-7R gene in CD4+ T-cell recovery in HIV-infected African patients receiving suppressive cART.	Genes Immun	2012
22841784	Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection.	Gastroenterology	2012
22457343	A genome-wide association study in progressive multiple sclerosis.	Multiple Sclerosis Journal	2012
22276564	Vitreal deposits in Val71Ala transthyretin amyloidosis.	Internal Medicine Journal	2012
22234924	Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection.	Hepatology	2012
21833088	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	Nature	2011
21507170	Voriconazole toxicity related to polymorphisms in CYP2C19.	Internal Medicine Journal	2011
21931540	IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: a cross-sectional study.	PLoS Med	2011
22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Ann Neurol	2011
21884576	Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort.	Genome Med	2011
20185587	Extreme lymphoproliferative disease and fatal autoimmune thrombocytopenia in FasL and TRAIL double-deficient mice.	Blood	2010
21152067	A transcription factor map as revealed by a genome-wide gene expression analysis of whole-blood mRNA transcriptome in multiple sclerosis.	PLoS ONE	2010
20812848	Biological determinants of immune reconstitution in HIV-infected patients receiving antiretroviral therapy: the role of interleukin 7 and interleukin 7 receptor Î± and microbial translocation.	J Infect Dis	2010
21049023	A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis.	PLoS ONE	2010
20711463	MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood.	PLoS ONE	2010
20463963	Novel approaches to detect serum biomarkers for clinical response to interferon-beta treatment in multiple sclerosis.	PLoS ONE	2010
20421878	A role for the atopy-associated gene PHF11 in T-cell activation and viability.	Immunology and Cell Biology	2010
20502484	Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis.	Nat Genet	2010
20097866	Functionally significant differences in expression of disease-associated IL-7 receptor alpha haplotypes in CD4 T cells and dendritic cells.	Journal of Immunology	2010
20190274	The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis.	Human Molecular Genetics	2010
20187771	Interleukin 7 receptor alpha chain haplotypes vary in their influence on multiple sclerosis susceptibility and response to interferon Beta.	Journal of Interferon and Cytokine Research	2010
20627928	Association of PHF11 polymorphisms with asthma and allergy.	Thorax	2010