Author details

Full Name

Xiaoyun Wu

Affiliation

ORCID

Career Start Year

2009

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36302897	Velcrin-induced selective cleavage of tRNA<sup>Leu</sup>(TAA) by SLFN12 causes cancer cell death.	Nat Chem Biol	2023
35084050	Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples.	Prostate	2022
35758042	Ibuprofen promotes p75 neurotrophin receptor expression through modifying promoter methylation and N6-methyladenosine-RNA-methylation in human gastric cancer cells.	Bioengineered	2022
35353015	Cell Painting predicts impact of lung cancer variants.	Mol Biol Cell	2022
34272366	Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.	Nat Commun	2021
32613204	Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling.	Nat Cancer	2020
32005668	Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12.	J Biol Chem	2020
33246941	Correction: Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12.	J Biol Chem	2020
31749907	Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing.	ACS Med Chem Lett	2019
31572460	The effect of miR-124-3p on cell proliferation and apoptosis in bladder cancer by targeting EDNRB.	Archives of Medical Science	2019
28315521	Systematic morphological profiling of human gene and allele function via Cell Painting.	Elife	2017
28678785	Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway.	Nature	2017
29195078	A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.	Cell	2017
29232558	High-throughput Phenotyping of Lung Cancer Somatic Mutations.	Cancer Cell	2017
26656089	Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.	Nat Chem Biol	2016
27147599	Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles.	Cancer Discov	2016
27478040	High-throughput Phenotyping of Lung Cancer Somatic Mutations.	Cancer Cell	2016
26197079	Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects.	PLoS One	2015
25448295	Building the Connectivity Map of epigenetics: chromatin profiling by quantitative targeted mass spectrometry.	Methods	2015
25897075	Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation.	Journal of Biological Chemistry	2015
22412383	Repression of germline RNAi pathways in somatic cells by retinoblastoma pathway chromatin complexes.	PLoS Genetics	2012
21205660	Cancer. Germ cell genes and cancer.	Science	2010
19616278	Upregulation of GRP78 in renal cell carcinoma and its significance.	Urology	2010
19920197	Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy.	Cancer Research	2009
19506556	A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants.	Nature	2009
19347029	Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells.	Oncogene	2009