Author details

Full Name

Drake Laface

Affiliation

Merck & Co. Inc.

ORCID

Career Start Year

1987

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
33127658	Antitumor efficacy of combined CTLA4/PD-1 blockade without intestinal inflammation is achieved by elimination of FcÎ³R interactions.	J Immunother Cancer	2020
33117369	Effective Anti-tumor Response by TIGIT Blockade Associated With FcÎ³R Engagement and Myeloid Cell Activation.	Front Immunol	2020
33329611	Corrigendum: Effective Anti-tumor Response by TIGIT Blockade Associated With Fc<i>Î³</i>R Engagement and Myeloid Cell Activation.	Front Immunol	2020
26015261	In vivo anti-tumor efficacy of afucosylated anti-CS1 monoclonal antibody produced in glycoengineered Pichia pastoris.	J Biotechnol	2015
24280935	Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells.	Mucosal Immunol	2014
24829407	Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia.	J Immunol	2014
24591025	Rapid detection and quantification of apolipoprotein L1 genetic variants and total levels in plasma by ultra-performance liquid chromatography/tandem mass spectrometry.	Rapid Commun Mass Spectrom	2013
22581824	IL-10 directly activates and expands tumor-resident CD8(+) T cells without de novo infiltration from secondary lymphoid organs.	Cancer Res	2012
22772566	IL-23 induces spondyloarthropathy by acting on ROR-Î³t+ CD3+CD4-CD8- entheseal resident T cells.	Nat Med	2012
21085745	A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma.	Mol Med	2011
22172723	IL-10 elicits IFNÎ³-dependent tumor immune surveillance.	Cancer Cell	2011
21799806	C17 prevents inflammatory arthritis and associated joint destruction in mice.	PLoS One	2011
21690321	Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling.	J Immunol	2011
21670317	IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass.	J Immunol	2011
21315784	Meeting report: regulatory myeloid cells.	Int Immunopharmacol	2011
20167120	Interleukin-17A upregulates receptor activator of NF-kappaB on osteoclast precursors.	Arthritis Res Ther	2010
19127252	Cancer-induced expansion and activation of CD11b+ Gr-1+ cells predispose mice to adenoviral-triggered anaphylactoid-type reactions.	Mol Ther	2009
19026560	IL-10 overexpression differentially affects cartilage matrix gene expression in response to TNF-alpha in human articular chondrocytes in vitro.	Cytokine	2008
18959626	Endogenous IL-10 regulates sepsis-induced thymic apoptosis and improves survival in septic IL-10 null mice.	Scand J Immunol	2008
18974247	Myeloid-derived suppressor cells in cancer cachexia syndrome: a new explanation for an old problem.	JPEN J Parenter Enteral Nutr	2008
17235356	Spleen but not tumor infiltration by dendritic and T cells is increased by intravenous adenovirus-Flt3 ligand injection.	Cancer Gene Ther	2007
17548519	MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis.	J Exp Med	2007
17265065	Adenoviral transduction is more efficient in alginate-derived chondrocytes than in monolayer chondrocytes.	Cell Tissue Res	2007
16251998	Dose-dependent improvements in outcome with adenoviral expression of interleukin-10 in a murine model of multisystem organ failure.	Gene Ther	2006
16514422	Adenovirus delivery provides extended interferon-alpha exposure and augments treatment of metastatic carcinoma.	Cancer Gene Ther	2006
16043097	Characterization of hemodynamic events following intravascular infusion of recombinant adenovirus reveals possible solutions for mitigating cardiovascular responses.	Mol Ther	2005
15897802	Functional modification of dendritic cells with recombinant adenovirus encoding interleukin 10 for the treatment of sepsis.	Shock	2005
15853912	In vivo transduction of thymic dendritic cells with adenovirus and its potential use in acute inflammatory diseases.	Scand J Immunol	2005
15588421	Influence of recombinant adenovirus on liver injury in endotoxicosis and its modulation by IL-10 expression.	J Endotoxin Res	2004
15534093	Impact of human neutralizing antibodies on antitumor efficacy of an oncolytic adenovirus in a murine model.	Clin Cancer Res	2004
15556685	Recombinant adenovirus-transduced human dendritic cells engineered to secrete interleukin-10 (IL-10) suppress Th1-type responses while selectively activating IL-10-producing CD4+ T cells.	Hum Immunol	2004
11907099	Increased survival in sepsis by in vivo adenovirus-induced expression of IL-10 in dendritic cells.	J Immunol	2002
11796006	Interleukin-10 fails to modulate low shear stress-induced neointimal hyperplasia.	J Surg Res	2002
11123343	Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitis.	J Immunol	2001
11356081	Specific depletion of human anti-adenovirus antibodies facilitates transduction in an in vivo model for systemic gene therapy.	Mol Ther	2001
11781661	Evaluation of endostatin antiangiogenesis gene therapy in vitro and in vivo.	Cancer Gene Ther	2001
11781656	Ex vivo purging by adenoviral p53 gene therapy does not affect NOD-SCID repopulating activity of human CD34+ cells.	Cancer Gene Ther	2001
11719454	Immunization with wild-type p53 gene sequences coadministered with Flt3 ligand induces an antigen-specific type 1 T-cell response.	Cancer Res	2001
11441115	Adenoviral delivery of human and viral IL-10 in murine sepsis.	J Immunol	2001
11553765	Targeted adenovirus-induced expression of IL-10 decreases thymic apoptosis and improves survival in murine sepsis.	Proc Natl Acad Sci U S A	2001
11134537	Extended lung expression and increased tissue localization of viral IL-10 with adenoviral gene therapy.	Proc Natl Acad Sci U S A	2001
10602026	TCR antagonist peptides induce formation of APC-T cell conjugates and activate a Rac signaling pathway.	Eur J Immunol	2000
10998329	Transgenic mice expressing human HLA and CD8 molecules generate HLA-restricted measles virus cytotoxic T lymphocytes of the same specificity as humans with natural measles virus infection.	Virology	2000
10605041	TNF-alpha receptor signaling and IL-10 gene therapy regulate the innate and humoral immune responses to recombinant adenovirus in the lung.	J Immunol	2000
9036949	Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses.	J Immunol	1997
9077559	Identification of Her-2/Neu CTL epitopes using double transgenic mice expressing HLA-A2.1 and human CD.8.	Hum Immunol	1997
8757947	Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506.	Int Immunol	1996
7530336	Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.	Nature	1995
8643108	A phage display system for detection of T cell receptor-antigen interactions.	Mol Immunol	1995
7578393	Cancer gene therapy using plasmid DNA: pharmacokinetic study of DNA following injection in mice.	Hum Gene Ther	1995

1 - 50 of 58

Sunil K Joshi

Knight Cancer Institute, Oregon Health & Science University

Career Start Year 1998

Number of shared co-authors 0

Seunghee Kim-Schulze

Icahn School of Medicine at Mount Sinai

Career Start Year 1996

Number of shared co-authors 0

Zhiya Yu

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1995

Number of shared co-authors 0

Cynthia Perez

Loyola University Chicago

Career Start Year 1995

Number of shared co-authors 1

PingAr Yang

University of Texas MD Anderson Cancer Center

Career Start Year 1995

Number of shared co-authors 2

Hui-Chen Hsu

Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham

Career Start Year 1993

Number of shared co-authors 2

Veena Kapoor

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1991

Number of shared co-authors 0

Jonathan S Serody

The University of North Carolina School of Medicine

Career Start Year 1991

Number of shared co-authors 2

Jeffrey A Medin

Medical College of Wisconsin

Career Start Year 1990

Number of shared co-authors 0

Sarfraz Memon

Center for Cancer Research, National Cancer Institute.

Career Start Year 1988

Number of shared co-authors 0

Kaoru Saijo

Helen Wills Neuroscience Institute, University of California berkeley

Career Start Year 1988

Number of shared co-authors 0

Ursula Grohmann

University of Perugia

Career Start Year 1988

Number of shared co-authors 0

Nicholas P Restifo

National Cancer Institute, National Institutes of Health (NIH)

Career Start Year 1985

Number of shared co-authors 1

Frances T Hakim

National Cancer Institute

Career Start Year 1984

Number of shared co-authors 0

Penelope A Morel

University of Pittsburgh

Career Start Year 1982

Number of shared co-authors 0

Lionel Feigenbaum

Science Applications International Corporation/Frederick

Career Start Year 1981

Number of shared co-authors 0

Robert E Lewis

University of Nebraska Medical Center

Career Start Year 1980

Number of shared co-authors 0

Wolfgang Holter

St. Anna Children's Hospital, Medical University of Vienna

Career Start Year 1980

Number of shared co-authors 0

John D Mountz

University of Alabama at Birmingham and Birmingham VA Medical Center.

Career Start Year 1978

Number of shared co-authors 3

Carl H June

University of Pennsylvania Department of Pathology & Laboratory Medicine

Career Start Year 1978

Number of shared co-authors 1

Peter S Linsley

8Benaroya Research Institute

Career Start Year 1978

Number of shared co-authors 0

Ronald E Gress

National Cancer Institute, National Institutes of Health

Career Start Year 1977

Number of shared co-authors 0

Howard A Young

Center for Cancer Research, National Cancer Institute

Career Start Year 1975

Number of shared co-authors 1

Paola Ricciardi-Castagnoli

A. Menarini Biomarkers Singapore Pte Ltd

Career Start Year 1973

Number of shared co-authors 0

Alan C Whitmore

University of North Carolina at Chapel Hill

Career Start Year 1973

Number of shared co-authors 0

Leonard D Shultz

The Jackson Laboratory Cancer Center

Career Start Year 1971

Number of shared co-authors 1

Ronald N Germain

National Institute of Allergy and Infectious Diseases, National Institutes of Health

Career Start Year 1971

Number of shared co-authors 0

Tak W Mak

Princess Margaret Cancer Centre, University Health Network

Career Start Year 1970

Number of shared co-authors 1

Shigeo Koyasu

RIKEN Center for Integrative Medical Sciences (IMS)

Career Start Year 1966

Number of shared co-authors 1

David W Scott

University of British Columbia

Career Start Year 1965

Number of shared co-authors 0

row(s) 1 - 30 of 30

Lyle L Moldawer

University of Florida College of Medicine.

Co-authored papers 17

Philip O Scumpia

David Geffen School of Medicine, University of California Los Angeles

Co-authored papers 7

Matthew J Delano

University of Michigan ann arbor

Co-authored papers 6

Michael J Clare-Salzler

University of Florida College of Medicine

Co-authored papers 5

Philip A Efron

University of Florida Health

Co-authored papers 5

Kindra M Kelly-Scumpia

David Geffen School of Medicine, University of California Los Angeles

Co-authored papers 4

Ricardo Ungaro

University of Florida College of Medicine

Co-authored papers 3

Daniel J Cua

Merck & Co., Inc.

Co-authored papers 3

Robert D Winfield

The University of Kansas Health System

Co-authored papers 3

Alex G Cuenca

Boston Children's Hospital

Co-authored papers 3

Kerri A O'Malley

Co-authored papers 2

Nico van Rooijen

Co-authored papers 2

Carl F Ware

Sanford Burnham Prebys Medical Discovery Institute

Co-authored papers 2

Gundula Schulze-Tanzil

Institute of Anatomy and Cell Biology, Paracelsus Medical University

Co-authored papers 2

Michael Matheny

American College of Medical Informatics, Department of Veteran Affairs, Harvard University T H Chan School of Public Health, Massachusetts Institute of Technology, The American Society for Clinical Investigation, University of Kentucky, Vanderbilt University Medical Center, Vanderbilt University Medical School

Co-authored papers 1

Alfred Ayala

Brown University

Co-authored papers 1

Nancy E Lane

Center for Musculoskeletal Health, University of California Davis School of Medicine

Co-authored papers 1

Dallas N Joiner

University of Florida College of Medicine and Dentistry

Co-authored papers 1

Alessandro Sette

Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology