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Author Details

William S Bush
Cleveland Institute for Computational Biology, Case Western Reserve University
2006
159
35
PMIDPaper TitleJournal TitlePublished Year
37881831NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's disease genetic and genomic knowledge.Alzheimers Dement2024
35943576T-cell receptor diversity in minimal change disease in the NEPTUNE study.Pediatr Nephrol2023
37945903Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.Nat Genet2023
37693521Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project.medRxiv2023
37693462Spatial Distribution of Missense Variants within Complement Proteins Associates with Age Related Macular Degeneration.medRxiv2023
37459083Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults.JAMA Neurol2023
37051669A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease.Alzheimers Dement2023
37440029Integrating Computational Approaches to Predict the Effect of Genetic Variants on Protein Stability in Retinal Degenerative Disease.Adv Exp Med Biol2023
36972313Tuberculosis severity associates with variants and eQTLs related to vascular biology and infection-induced inflammation.PLoS Genet2023
37333116An X Chromosome Transcriptome Wide Association Study Implicates ARMCX6 in Alzheimer's Disease.bioRxiv2023
37260021Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews.Alzheimers Dement2023
36580636Anemia and Erythrocyte Indices Are Associated With Neurocognitive Performance Across Multiple Ability Domains in Adults With HIV.J Acquir Immune Defic Syndr2023
36872133Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry.Eur Urol2023
36685236Does hand position affect orienting when no action is required? An electrophysiological study.Front Neurosci2023
36539198Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.Alzheimers Dement2023
36929083Pharmacogenomic and Statistical Analysis.Methods Mol Biol2023
34127801Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24.Prostate Cancer Prostatic Dis2022
35383839Genetic architecture of RNA editing regulation in Alzheimer's disease across diverse ancestral populations.Hum Mol Genet2022
35508071Integration of Protein Structure and Population-Scale DNA Sequence Data for Disease Gene Discovery and Variant Interpretation.Annu Rev Biomed Data Sci2022
35379992New insights into the genetic etiology of Alzheimer's disease and related dementias.Nat Genet2022
35552371Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.Brain2022
34890169Packaging Biocomputing Software to Maximize Distribution and Reuse.Pac Symp Biocomput2022
35210353An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns.Genome Res2022
35031163A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry.Eur Urol2022
32930425African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer.Int J Cancer2021
33716716<i>TNFRSF1B</i> Gene Variants and Related Soluble TNFR2 Levels Impact Resilience in Alzheimer's Disease.Front Aging Neurosci2021
33623038Polygenic hazard score is associated with prostate cancer in multi-ethnic populations.Nat Commun2021
33874910Modeling transcriptional regulation using gene regulatory networks based on multi-omics data sources.BMC Bioinformatics2021
35005195Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease.Alzheimers Dement (Amst)2021
35003209A Haptoglobin Exon Copy Number Variant Associates With HIV-Associated Neurocognitive Impairment in European and African-Descent Populations.Front Genet2021
34793544Replication of European hypertension associations in a case-control study of 9,534 African Americans.PLoS One2021
34832643Interaction between <i>M. tuberculosis</i> Lineage and Human Genetic Variants Reveals Novel Pathway Associations with Severity of TB.Pathogens2021
34195939Higher CSF Ferritin Heavy-Chain (Fth1) and Transferrin Predict Better Neurocognitive Performance in People with HIV.Mol Neurobiol2021
33400784Methylome-wide Analysis Reveals Epigenetic Marks Associated With Resistance to Tuberculosis in Human Immunodeficiency Virus-Infected Individuals From East Africa.J Infect Dis2021
33398198Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.Nat Genet2021
33473200Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.Nat Genet2021
32409115A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry.Eur Urol2020
31797629Frequency of ClinVar Pathogenic Variants in Chronic Kidney Disease Patients Surveyed for Return of Research Results at a Cleveland Public Hospital.Pac Symp Biocomput2020
31797624Hadoop and PySpark for reproducibility and scalability of genomic sequencing studies.Pac Symp Biocomput2020
33005167Editorial: The Importance of Diversity in Precision Medicine Research.Front Genet2020
32597797Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer's Disease Cohort.J Alzheimers Dis2020
32847609PSCAN: Spatial scan tests guided by protein structures improve complex disease gene discovery and signal variant detection.Genome Biol2020
32844198Genetic variants and functional pathways associated with resilience to Alzheimer's disease.Brain2020
32393777Protein-altering germline mutations implicate novel genes related to lung cancer development.Nat Commun2020
31021849Catechol-O-methyltransferase polymorphism Val158Met is associated with distal neuropathic pain in HIV-associated sensory neuropathy.AIDS2019
33312764GWAS and Beyond: Using Omics Approaches to Interpret SNP Associations.Curr Genet Med Rep2019
30026132Nuclear-Mitochondrial interactions influence susceptibility to HIV-associated neurocognitive impairment.Mitochondrion2019
30100616Fine-mapping analysis of a chromosome 2 region linked to resistance to Mycobacterium tuberculosis infection in Uganda reveals potential regulatory variants.Genes Immun2019
30209774Cerebrospinal Fluid Ceruloplasmin, Haptoglobin, and Vascular Endothelial Growth Factor Are Associated with Neurocognitive Impairment in Adults with HIV Infection.Mol Neurobiol2019
29857119Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project.Genomics2019
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Collaborators

Dana C Crawford
Cleveland Institute for Computational Biology, Case Western Reserve University
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Jonathan L Haines
Cleveland Institute for Computational Biology, Case Western Reserve University
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Marylyn D Ritchie
Center for Systems Genomics, Pennsylvania State University, University Park
Co-authored papers 26
Margaret A Pericak-Vance
Co-authored papers 23
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Christopher A Haiman
University of Southern California
Co-authored papers 18
Loic Le Marchand
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Charles Kooperberg
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Ulrike Peters
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Donald Franklin
University of California San Diego
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Fredrick R Schumacher
Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine
Co-authored papers 10
Ronald J Ellis
University of California
Co-authored papers 10
Demetrius Albanes
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Zsofia Kote-Jarai
The Institute of Cancer Research
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Robin J Leach
University of Texas Health San Antonio
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Gyorgy Petrovics
Henry Jackson Foundation for the Advancement of Military Medicine (HJF)
Co-authored papers 9
Eric Boerwinkle
Baylor College of Medicine
Co-authored papers 9
Alison M Goate
Icahn School of Medicine at Mount Sinai
Co-authored papers 9
John A Capra
Bakar Computational Health Sciences Institute, University of California san francisco
Co-authored papers 9
Jeannette T Bensen
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