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Author Details

Gung-Wei Chirn
1994
25
17
PMIDPaper TitleJournal TitlePublished Year
29403037The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168.Nature Cell Biology2018
28031481Piwi proteins interact with a broad proportion of the oocyte transcriptome.RNA2017
28581676Comprehensive genomic profiling of different subtypes of nasopharyngeal carcinoma reveals similarities and differences to guide targeted therapy.Cancer2017
26578579Unique transposon landscapes are pervasive across Drosophila melanogaster genomes.Nucleic Acids Res2015
26588211Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals.PLoS Genet2015
24178561Small RNA library construction from minute biological samples.Methods in Molecular Biology2014
25336588The capacity of target silencing by Drosophila PIWI and piRNAs.RNA2014
25267525Transposable element dynamics and PIWI regulation impacts lncRNA and gene expression diversity in Drosophila ovarian cell cultures.Genome Research2014
23610421Holo-TFIID controls the magnitude of a transcription burst and fine-tuning of transcription.Proceedings of the National Academy of Sciences of the United States of America2013
24204722Possible formation of mitochondrial-RNA containing chimeric or trimeric RNA implies a post-transcriptional and post-splicing mechanism for RNA fusion.PLoS ONE2013
23329696RNAi pathways contribute to developmental history-dependent phenotypic plasticity in C. elegans.RNA2013
23012419Single nucleotide in the MTF-1 binding site can determine metal-specific transcription activation.Proceedings of the National Academy of Sciences of the United States of America2012
18822150Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profiles.BioData Mining2008
18066055Integrating high-content screening and ligand-target prediction to identify mechanism of action.Nature Chemical Biology2008
17370256From proteomics to systems biology of bacterial pathogens: approaches, tools, and applications.Proteomics2007
17463246Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.Science2007
16202129Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural networks.BMC Bioinformatics2005
15922185Development of comprehensive functional genomic screens to identify novel mediators of osteoarthritis.Osteoarthritis and Cartilage2005
15640145Multiple retropseudogenes from pluripotent cell-specific gene expression indicates a potential signature for novel gene identification.Journal of Biological Chemistry2005
14506290Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.Proc Natl Acad Sci U S A2003
12541280Rapid expression cloning of receptors using epitope-tagged ligands and high-speed cell sorting.Cytometry. Part A : the journal of the International Society for Analytical Cytology2003
14514886Genome-scale functional profiling of the mammalian AP-1 signaling pathway.Proc Natl Acad Sci U S A2003
9764779HIV protease genotype and viral sensitivity to HIV protease inhibitors following saquinavir therapy.AIDS1998
8795038Complementary classification approaches for protein sequences.Protein Eng1996
8052532Discovering active motifs in sets of related protein sequences and using them for classification.Nucleic Acids Res1994
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Courant Institute of Mathematical Sciences, New York University
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Genomics Institute of the Novartis Research Foundation
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Genomics Institute of the Novartis Research Foundation
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University of Maine
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Philip Morris International Research Laboratories Pte. Ltd
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The Salk Institute
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Massachusetts Institute of Technology
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Broad Institute of MIT and Harvard
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Broad Institute of MIT and Harvard
Co-authored papers 1