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Author Details

Alex Vassilev
National Institute of Child Health & Human Development, National Institutes of Health
1991
34
25
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35063131Selective elimination of pluripotent stem cells by PIKfyve specific inhibitors.Stem Cell Reports2022
33685990Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells.Cancer Res2021
30806145A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis.Autophagy2019
28125050Links between DNA Replication, Stem Cells and Cancer.Genes (Basel)2017
27144335Identification of genes that are essential to restrict genome duplication to once per cell division.Oncotarget2016
24901367Defective i6A37 modification of mitochondrial and cytosolic tRNAs results from pathogenic mutations in TRIT1 and its substrate tRNA.PLoS Genet2014
23861403A Ca2+-dependent mechanism of neuronal survival mediated by the microtubule-associated protein p600.J Biol Chem2013
21555516Assembly of the human origin recognition complex occurs through independent nuclear localization of its components.J Biol Chem2011
20596238Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors.Nat Commun2010
19015152Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex.Nucleic Acids Res2009
16650748Regulating the licensing of DNA replication origins in metazoa.Curr Opin Cell Biol2006
17066079The BAH domain facilitates the ability of human Orc1 protein to activate replication origins in vivo.EMBO J2006
16762929Genetic analysis of human Orc2 reveals specific domains that are required in vivo for assembly and nuclear localization of the origin recognition complex.J Biol Chem2006
16537645Ubiquitylation, phosphorylation and Orc2 modulate the subcellular location of Orc1 and prevent it from inducing apoptosis.J Cell Sci2006
16214886p600, a unique protein required for membrane morphogenesis and cell survival.Proc Natl Acad Sci U S A2005
15199143Role for Cdk1 (Cdc2)/cyclin A in preventing the mammalian origin recognition complex's largest subunit (Orc1) from binding to chromatin during mitosis.Mol Cell Biol2004
15572691Nonphosphorylated human La antigen interacts with nucleolin at nucleolar sites involved in rRNA biogenesis.Mol Cell Biol2004
15213244Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10.J Biochem2004
11358867TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm.Genes Dev2001
11279013ATP-dependent nucleosome remodeling and histone hyperacetylation synergistically facilitate transcription of chromatin.J Biol Chem2001
10777508p300/CBP-associated factor histone acetyltransferase processing of a peptide substrate. Kinetic analysis of the catalytic mechanism.J Biol Chem2000
10882143HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF.Mol Cell2000
10766811p300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator-enhancer complex.J Biol Chem2000
10753971Acetylation of novel sites in the nucleosomal binding domain of chromosomal protein HMG-14 by p300 alters its interaction with nucleosomes.J Biol Chem2000
9880483Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates.J Biol Chem1999
9727487Crystal structure of a GCN5-related N-acetyltransferase: Serratia marcescens aminoglycoside 3-N-acetyltransferase.Cell1998
10384313TBP-associated factors in the PCAF histone acetylase complex.Cold Spring Harb Symp Quant Biol1998
9885574The 400 kDa subunit of the PCAF histone acetylase complex belongs to the ATM superfamily.Mol Cell1998
9710589An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300.Mol Cell Biol1998
9744860DNA damage activates p53 through a phosphorylation-acetylation cascade.Genes Dev1998
7622605The levels of ubiquitinated histone H2A are highly upregulated in transformed human cells: partial colocalization of uH2A clusters and PCNA/cyclin foci in a fraction of cells in S-phase.J Cell Sci1995
7895731The human keratinocyte two-dimensional protein database (update 1994): towards an integrated approach to the study of cell proliferation, differentiation and skin diseases.Electrophoresis1994
8004012Localization and partial characterization of a rat ovarian granulosa cell protein with a monoclonal antibody.Biol Cell1993
1756311Expression of the nuclear protein mitotin in differentiating in vitro HL 60 cells.Biol Cell1991
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Dana Farber Cancer Institute
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Co-authored papers 4
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Co-authored papers 3
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Co-authored papers 2
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The Rockefeller University
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Robert McFarland
Newcastle University
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Release 1.2