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Author Details

Alex W Hewitt
Menzies Institute for Medical Research, University of Tasmania
2001
385
61
PMIDPaper TitleJournal TitlePublished Year
37657710A semi-automated pipeline for quantifying drusen-like deposits in human induced pluripotent stem cell-derived retinal pigment epithelium cells.SLAS Technol2024
37634759Genome-Wide Meta-analysis Identifies Risk Loci and Improves Disease Prediction of Age-Related Macular Degeneration.Ophthalmology2024
37800621Genetic risk of glaucoma is associated with vascular and retinal nerve fibre wedge defects.Acta Ophthalmol2024
35970205Association Between Body Mass Index and Primary Open Angle Glaucoma in Three Cohorts.Am J Ophthalmol2023
37594450Distribution of Axial Length in Australians of Different Age Groups, Ethnicities, and Refractive Errors.Transl Vis Sci Technol2023
37986775WITHDRAWN: Genome-wide risk prediction of primary open-angle glaucoma across multiple ancestries.medRxiv2023
37536973Study profile: the Genetics of Glaucoma Study.BMJ Open2023
35840489RNA-targeting strategies as a platform for ocular gene therapy.Prog Retin Eye Res2023
37386247Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci.Nat Genet2023
37016462Predictive factors for treatment outcomes with intravitreal anti-vascular endothelial growth factor injections in diabetic macular edema in clinical practice.Int J Retina Vitreous2023
37407499Dr AI will see you now.Clin Exp Ophthalmol2023
37201334Disentangling the genetic overlap and causal relationships between primary open-angle glaucoma, brain morphology and four major neurodegenerative disorders.EBioMedicine2023
37296104A village in a dish model system for population-scale hiPSC studies.Nat Commun2023
36513856Cost-effectiveness of polygenic risk profiling for primary open-angle glaucoma in the United Kingdom and Australia.Eye (Lond)2023
36834828Development of a CRISPRi Human Retinal Pigmented Epithelium Model for Functional Study of Age-Related Macular Degeneration Genes.Int J Mol Sci2023
36535572TAK1 blockade as a therapy for retinal neovascularization.Pharmacol Res2023
36867133Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study.Invest Ophthalmol Vis Sci2023
36675282Seeing Neurodegeneration in a New Light Using Genetically Encoded Fluorescent Biosensors and iPSCs.Int J Mol Sci2023
36565701Is the disease risk and penetrance in Leber hereditary optic neuropathy actually low?Am J Hum Genet2023
36795578Knockout of AMD-associated gene <i>POLDIP2</i> reduces mitochondrial superoxide in human retinal pigment epithelial cells.Aging (Albany NY)2023
34505266Image-Based Quantitation of Kainic Acid-Induced Excitotoxicity as a Model of Neurodegeneration in Human iPSC-Derived Neurons.Methods Mol Biol2022
35680963AAV2-mediated gene therapy for Bietti crystalline dystrophy provides functional CYP4V2 in multiple relevant cell models.Sci Rep2022
35409401Identifying Genetic Biomarkers Predicting Response to Anti-Vascular Endothelial Growth Factor Injections in Diabetic Macular Edema.Int J Mol Sci2022
35531644Fundoscopy use in neurology departments and the utility of smartphone photography: a prospective prevalence and crossover diagnostic accuracy study amongst neurology inpatients.Eur J Neurol2022
35819290The Relationship Between Fetal Growth and Retinal Nerve Fiber Layer Thickness in a Cohort of Young Adults.Transl Vis Sci Technol2022
35363088An Integrative Multi-Omics Analysis Reveals MicroRNA-143 as a Potential Therapeutic to Attenuate Retinal Angiogenesis.Nucleic Acid Ther2022
35389779Single-cell eQTL mapping identifies cell type-specific genetic control of autoimmune disease.Science2022
35749127Sonic Hedgehog Intron Variant Associated With an Unusual Pediatric Cortical Cataract.Invest Ophthalmol Vis Sci2022
35446358Association of Novel Loci With Keratoconus Susceptibility in a Multitrait Genome-Wide Association Study of the UK Biobank Database and Canadian Longitudinal Study on Aging.JAMA Ophthalmol2022
36778138Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma.Cell Genom2022
36453132Lysosomal alterations and decreased electrophysiological activity in CLN3 disease patient-derived cortical neurons.Dis Model Mech2022
36249683The <i>APOE</i> E4 Allele Is Associated with Faster Rates of Neuroretinal Thinning in a Prospective Cohort Study of Suspect and Early Glaucoma.Ophthalmol Sci2022
36306122Attitudes Toward Glaucoma Genetic Risk Assessment in Unaffected Individuals.Transl Vis Sci Technol2022
36355370Association of High Polygenic Risk With Visual Field Worsening Despite Treatment in Early Primary Open-Angle Glaucoma.JAMA Ophthalmol2022
35985662Diagnostic yield of candidate genes in an Australian corneal dystrophy cohort.Mol Genet Genomic Med2022
36219697The VEGAS Platform Is Unsuitable for Mammalian Directed Evolution.ACS Synth Biol2022
36217948Specifications of the ACMG/AMP variant curation guidelines for myocilin: Recommendations from the clingen glaucoma expert panel.Hum Mutat2022
36005887propeller: testing for differences in cell type proportions in single cell data.Bioinformatics2022
33725267Culture Variabilities of Human iPSC-Derived Cerebral Organoids Are a Major Issue for the Modelling of Phenotypes Observed in Alzheimer's Disease.Stem Cell Rev Rep2022
35227220The effect of insulin on response to intravitreal anti-VEGF injection in diabetic macular edema in type 2 diabetes mellitus.BMC Ophthalmol2022
35244489A Taxonomic and Phylogenetic Classification of Diverse Base Editors.CRISPR J2022
35302538Diagnostic Accuracy of Artificial Intelligence in Glaucoma Screening and Clinical Practice.J Glaucoma2022
35166105Combinatorial Approach of Binary Colloidal Crystals and CRISPR Activation to Improve Induced Pluripotent Stem Cell Differentiation into Neurons.ACS Appl Mater Interfaces2022
34486472<i>In Utero</i> Exposure to Smoking and Alcohol, and Passive Smoking during Childhood: Effect on the Retinal Nerve Fibre Layer in Young Adulthood.Ophthalmic Epidemiol2022
34774858Attitudes Towards Polygenic Risk Testing in Individuals with Glaucoma.Ophthalmol Glaucoma2022
34505269CRISPR/Cas-Mediated Knock-in of Genetically Encoded Fluorescent Biosensors into the AAVS1 Locus of Human-Induced Pluripotent Stem Cells.Methods Mol Biol2022
32730956Cardiovascular Disease Predicts Structural and Functional Progression in Early Glaucoma.Ophthalmology2021
36246177Genetic Risk of Cardiovascular Disease Is Associated with Macular Ganglion Cell-Inner Plexiform Layer Thinning in an Early Glaucoma Cohort.Ophthalmol Sci2021
33627673Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries.Nat Commun2021
33737652Time spent outdoors in childhood is associated with reduced risk of myopia as an adult.Sci Rep2021
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Eranga N Vithana
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E-Shyong Tai
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Jessica N Cooke Bailey
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Matthew A Brown
Co-authored papers 16
Yik-Ying Teo
Co-authored papers 15
Andrew J Lotery
University of Southampton
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Yingchang Lu
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Albert Hofman
Harvard T.H. Chan School of Public Health
Co-authored papers 14
Paul N Baird
The University of Melbourne
Co-authored papers 14
Sarah E Medland
Co-authored papers 13
Ananth C Viswanathan
Co-authored papers 13
Kent D Taylor
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Release 1.2