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Author Details

Jason M Held
2004
49
25
PMIDPaper TitleJournal TitlePublished Year
36470535Proteins in Tumor-Derived Plasma Extracellular Vesicles Indicate Tumor Origin.Molecular and Cellular Proteomics2023
37914932Epigenetic regulation during cancer transitions across 11 tumour types.Nature2023
37910615UNC-49 is a redox-sensitive GABA receptor that regulates the mitochondrial unfolded protein response cell nonautonomously.2023
37961519Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages.bioRxiv2023
35604553Automating Assignment, Quantitation, and Biological Annotation of Redox Proteomics Datasets with ProteoSushi.Methods in Molecular Biology2022
35421237Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT-3102.Clinical Cancer Research2022
33596420Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1.Cell Reports2021
34056901ProteoSushi: A Software Tool to Biologically Annotate and Quantify Modification-Specific, Peptide-Centric Proteomics Data Sets.Journal of Proteome Research2021
33826887NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation.Cell Reports2021
31368359Redox Systems Biology: Harnessing the Sentinels of the Cysteine Redoxome.Antioxidants and Redox Signaling2020
31964804Spatial and temporal alterations in protein structure by EGF regulate cryptic cysteine oxidation.Science Signaling2020
32150535ProteoClade: A taxonomic toolkit for multi-species and metaproteomic analysis.PLoS Computational Biology2020
32814773Systems level profiling of arginine starvation reveals MYC and ERK adaptive metabolic reprogramming.Cell Death and Disease2020
32916549A clickable probe for versatile characterization of S-nitrosothiols.Redox Biol2020
32521270Phospho-Ser<sup>784</sup>-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer.Cell Rep2020
29472518Mass Spectrometry-Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers.Cancer Res2018
28122247Arginine Deprivation Inhibits the Warburg Effect and Upregulates Glutamine Anaplerosis and Serine Biosynthesis in ASS1-Deficient Cancers.Cell Reports2017
28348404Proteogenomic integration reveals therapeutic targets in breast cancer xenografts.Nat Commun2017
28902398Using ProteomeScout: A Resource of Post-Translational Modifications, Their Experiments, and the Proteins That They Annotate.Current Protocols in Bioinformatics2017
28790197Breast tumors educate the proteome of stromal tissue in an individualized but coordinated manner.Sci Signal2017
28440318Corrigendum: Proteogenomic integration reveals therapeutic targets in breast cancer xenografts.Nat Commun2017
28827567Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry.Nat Commun2017
27172180Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans.G3: Genes, Genomes, Genetics2016
26398777Multiplexed, Scheduled, High-Resolution Parallel Reaction Monitoring on a Full Scan QqTOF Instrument with Integrated Data-Dependent and Targeted Mass Spectrometric Workflows.Anal Chem2015
25693799Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma.Mol Cell Proteomics2015
24970821RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth.Oncotarget2014
25551439Comparative analyses of proteins from Haemophilus influenzae biofilm and planktonic populations using metabolic labeling and mass spectrometry.BMC Microbiol2014
24853916Variation and quantification among a target set of phosphopeptides in human plasma by multiple reaction monitoring and SWATH-MS2 data-independent acquisition.Electrophoresis2014
23710360Label-Free Quantitation and Mapping of the ErbB2 Tumor Receptor by Multiple Protease Digestion with Data-Dependent (MS1) and Data-Independent (MS2) Acquisitions.Int J Proteomics2013
24014403Targeted quantitation of acetylated lysine peptides by selected reaction monitoring mass spectrometry.Methods Mol Biol2013
23689285Design, implementation and multisite evaluation of a system suitability protocol for the quantitative assessment of instrument performance in liquid chromatography-multiple reaction monitoring-MS (LC-MRM-MS).Mol Cell Proteomics2013
23576753Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.Proc Natl Acad Sci U S A2013
22159599Regulatory control or oxidative damage? Proteomic approaches to interrogate the role of cysteine oxidation status in biological processes.Mol Cell Proteomics2012
22309216Lectin chromatography/mass spectrometry discovery workflow identifies putative biomarkers of aggressive breast cancers.J Proteome Res2012
22511757Inhibition of lipid signaling enzyme diacylglycerol kinase epsilon attenuates mutant huntingtin toxicity.J Biol Chem2012
22669764Ligand binding promotes CDK-dependent phosphorylation of ER-alpha on hinge serine 294 but inhibits ligand-independent phosphorylation of serine 305.Mol Cancer Res2012
21685499Mass spectrometric identification of novel lysine acetylation sites in huntingtin.Mol Cell Proteomics2011
21196577Quantitative mapping of reversible mitochondrial Complex I cysteine oxidation in a Parkinson disease mouse model.J Biol Chem2011
21514405Confident identification of 3-nitrotyrosine modifications in mass spectral data across multiple mass spectrometry platforms.J Proteomics2011
21562563N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans.Nature2011
20233844Targeted quantitation of site-specific cysteine oxidation in endogenous proteins using a differential alkylation and multiple reaction monitoring mass spectrometry approach.Mol Cell Proteomics2010
20406983ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.Cancer Res2010
18984578Systematic mapping of posttranslational modifications in human estrogen receptor-alpha with emphasis on novel phosphorylation sites.Mol Cell Proteomics2009
19697948Preferentially increased nitration of alpha-synuclein at tyrosine-39 in a cellular oxidative model of Parkinson's disease.Anal Chem2009
19561596Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma.Nat Biotechnol2009
18367407A novel serine phosphorylation site detected in the N-terminal domain of estrogen receptor isolated from human breast cancer cells.J Am Soc Mass Spectrom2008
16913876DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid.Aging Cell2006
15939799Vitamin K3 (menadione)-induced oncosis associated with keratin 8 phosphorylation and histone H3 arylation.Mol Pharmacol2005
15569358Lipophilic regulator of a developmental switch in Caenorhabditis elegans.Aging Cell2004
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