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Author Details

Siân Jones
2002
62
49
PMIDPaper TitleJournal TitlePublished Year
35595835Automated next-generation profiling of genomic alterations in human cancers.Nat Commun2022
32866655Inherited Rare, Deleterious Variants in ATM Increase Lung Adenocarcinoma Risk.J Thorac Oncol2020
31655296Randomized Phase II Study of Paclitaxel plus Alisertib versus Paclitaxel plus Placebo as Second-Line Therapy for SCLC: Primary and Correlative Biomarker Analyses.J Thorac Oncol2020
31506389Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade.Clin Cancer Res2019
30185652A machine learning approach for somatic mutation discovery.Sci Transl Med2018
30027257Regarding the Congruence Between 2 Circulating Tumor DNA Sequencing Assays.JAMA Oncol2018
27340278Whole-Exome Sequencing of Salivary Gland Mucoepidermoid Carcinoma.Clin Cancer Res2017
28814544Direct detection of early-stage cancers using circulating tumor DNA.Sci Transl Med2017
28489996Cancer-Associated Mutations in Endometriosis without Cancer.N Engl J Med2017
29062530: Developing individuals with lived-experience of health and social care as facilitators to deliver a course to enhance public involvement in research - a Welsh perspective.Research Involvement and Engagement2017
29061967High grade serous ovarian carcinomas originate in the fallopian tube.Nat Commun2017
27650546CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network.Oncotarget2016
27196778Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors.Mol Cancer Ther2016
25240578Familial and sporadic pancreatic cancer share the same molecular pathogenesis.Fam Cancer2015
25877891Personalized genomic analyses for cancer mutation discovery and interpretation.Sci Transl Med2015
25406187Notch1 mutations are drivers of oral tumorigenesis.Cancer Prev Res (Phila)2015
25428220Activating STAT6 mutations in follicular lymphoma.Blood2015
26506520Prevalence of deleterious ATM germline mutations in gastric cancer patients.Oncotarget2015
26416732The genomic landscape of response to EGFR blockade in colorectal cancer.Nature2015
26154128Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients.Nat Commun2015
26374070Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA.Nat Commun2015
24880341Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas.Nature Genetics2014
25305755Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors.Nat Genet2014
24435047Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.Blood2014
24140581The genetic landscape of anaplastic astrocytoma.Oncotarget2014
25233892Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes.Nat Commun2014
24634382Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment.Clin Cancer Res2014
23202128Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.Nat Genet2013
23729402Therapeutic potential of the poly(ADP-ribose) polymerase inhibitor rucaparib for the treatment of sporadic human ovarian cancer.Mol Cancer Ther2013
22102435Low-grade serous carcinomas of the ovary contain very few point mutations.Journal of Pathology2012
22302350Somatic mutations in the Notch, NF-KB, PIK3CA, and Hedgehog pathways in human breast cancers.Genes Chromosomes Cancer2012
22991414Clinical significance of the genetic landscape of pancreatic cancer and implications for identification of potential long-term survivors.Clinical Cancer Research2012
22009941Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types.Hum Mutat2012
21278246Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer.Clin Cancer Res2011
21435433Somatic mutations of PPP2R1A in ovarian and uterine carcinomas.American Journal of Pathology2011
21163964The genetic landscape of the childhood cancer medulloblastoma.Science2011
21135251Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer.Mol Cancer Ther2011
20826764Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma.Science2010
20981102Distant metastasis occurs late during the genetic evolution of pancreatic cancer.Nature2010
19701947The APC Variant p.Glu1317Gln predisposes to colorectal adenomas by a novel mechanism of relaxing the target for tumorigenic somatic APC mutations.Human Mutation2009
19264984Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene.Science2009
19584151SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.Clin Cancer Res2009
19351817Genetic mutations associated with cigarette smoking in pancreatic cancer.Cancer Res2009
19349352Frequent activating mutations of PIK3CA in ovarian clear cell carcinoma.Am J Pathol2009
19228619IDH1 and IDH2 mutations in gliomas.N Engl J Med2009
18852474Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers.Proc Natl Acad Sci U S A2008
18515411Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3.Gut2008
18337506Comparative lesion sequencing provides insights into tumor evolution.Proc Natl Acad Sci U S A2008
18380902Genome-wide linkage scan for colorectal cancer susceptibility genes supports linkage to chromosome 3q.BMC Cancer2008
18772397Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.Science2008
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Texas Children's Hospital
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Johns Hopkins University
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National Human Genome Research Institute, US National Institutes of Health
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Uppsala University
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University of California San Diego
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Convergence Institute, Johns Hopkins University
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David Geffen School of Medicine at university of california los angeles
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Vanderbilt University Medical Center
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University of South Carolina
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