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Author Details

Tineke L Lenstra
the Netherlands Cancer Institute, Oncode Institute
2010
34
16
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37824008Measuring Transcription Dynamics of Individual Genes Inside Living Cells.Methods Mol Biol2024
37127821Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting.Nat Struct Mol Biol2023
37995691Locus-specific proteome decoding reveals Fpt1 as a chromatin-associated negative regulator of RNA polymerase III assembly.Mol Cell2023
37645793Competition between transcription and loop extrusion modulates promoter and enhancer dynamics.Res Sq2023
36987884Transcription factor clusters enable target search but do not contribute to target gene activation.Nucleic Acids Res2023
37162887Competition between transcription and loop extrusion modulates promoter and enhancer dynamics.bioRxiv2023
35137218Transcription-replication coordination revealed in single live cells.Nucleic Acids Res2022
35710138Transcriptional regulation and chromatin architecture maintenance are decoupled functions at the <i>Sox2</i> locus.Genes Dev2022
36250630Quantifying how post-transcriptional noise and gene copy number variation bias transcriptional parameter inference from mRNA distributions.Elife2022
35337845Following the tracks: How transcription factor binding dynamics control transcription.Biophys J2022
34278333Optimized protocol for single-molecule RNA FISH to visualize gene expression in <i>S. cerevisiae</i>.STAR Protoc2021
34661296The Hda1 histone deacetylase limits divergent non-coding transcription and restricts transcription initiation frequency.EMBO J2021
32544389RNA Pol II Length and Disorder Enable Cooperative Scaling of Transcriptional Bursting.Mol Cell2020
33377036Single-Molecule Fluorescence Imaging in Living <i>Saccharomyces cerevisiae</i> Cells.STAR Protoc2020
31101674Live-cell imaging reveals the interplay between transcription factors, nucleosomes, and bursting.EMBO J2019
31284216Visualizing transcription: key to understanding gene expression dynamics.Curr Opin Chem Biol2019
30203048Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism.Nucleic Acids Res2018
27110320Single-Molecule mRNA Detection in Live Yeast.Curr Protoc Mol Biol2016
27145880Transcription Dynamics in Living Cells.Annu Rev Biophys2016
26700642A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.BMC Biol2015
26549684Single-Molecule Imaging Reveals a Switch between Spurious and Functional ncRNA Transcription.Mol Cell2015
24952590Cell cycle population effects in perturbation studies.Mol Syst Biol2014
24766815Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.Cell2014
23532335Dysregulated RasGRP1 responds to cytokine receptor input in T cell leukemogenesis.Sci Signal2013
24324601The role of Ctk1 kinase in termination of small non-coding RNAs.PLoS One2013
24037263Kinetochore function and chromosome segregation rely on critical residues in histones H3 and H4 in budding yeast.Genetics2013
23599000A novel role for Sem1 and TREX-2 in transcription involves their impact on recruitment and H2B deubiquitylation activity of SAGA.Nucleic Acids Res2013
23746449Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation.Cell Rep2013
22572961The discrepancy between chromatin factor location and effect.Nucleus2012
21459853Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs.Nucleic Acids Res2011
21998594A barcode screen for epigenetic regulators reveals a role for the NuB4/HAT-B histone acetyltransferase complex in histone turnover.PLoS Genet2011
21596317The specificity and topology of chromatin interaction pathways in yeast.Mol Cell2011
21291527Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms.Epigenetics Chromatin2011
21145464Functional overlap and regulatory links shape genetic interactions between signaling pathways.Cell2010
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Collaborators

Frank C P Holstege
Princess Maxima Center for Pediatric Oncology
Co-authored papers 14
Philip Lijnzaad
Princess Maxima Center for Pediatric Oncology
Co-authored papers 6
Patrick Kemmeren
Princess Maxima Center for Pediatric Oncology
Co-authored papers 6
Dik van Leenen
Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University
Co-authored papers 6
Mariel O Brok
Princess Maxima Center for Pediatric Oncology
Co-authored papers 5
Joris J Benschop
Center for Molecular Medicine, University Medical Center Utrecht
Co-authored papers 5
Fred van Leeuwen
Netherlands Cancer Institute, University of Amsterdam
Co-authored papers 5
Marian J A Groot Koerkamp
Princess Maxima Center for Pediatric Oncology Research
Co-authored papers 5
Thanasis Margaritis
Princess Maxima Center for Pediatric Oncology
Co-authored papers 4
Katrin Sameith
Center for Molecular and Cellular Bioengineering
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Tibor van Welsem
Netherlands Cancer Institute
Co-authored papers 4
Sander R van Hooff
Princess Maxima Center for Pediatric Oncology
Co-authored papers 4
Nathalie Brabers
University Medical Centre Utrecht, Universiteitsweg
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Cheuk W Ko
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Sake van Wageningen
Oncode Institute, The Netherlands Cancer Institute
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Berend Snel
Utrecht University
Co-authored papers 3
Loes A L van de Pasch
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 3
Eva Apweiler
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 3
Iris J E Stulemeijer
Netherlands Cancer Institute
Co-authored papers 2
Antony J Miles
University Medical Centre Utrecht, Universiteitsweg
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Linda V Bakker
Wageningen University and Research
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Nevan J Krogan (CM4AI)
University of California San Francisco
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Dorothea Fiedler
Leibniz Forschungsinstitut fur Molekulare Pharmakologie (FMP)
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Deepani W Poramba-Liyanage
Utrecht University Utrecht The Netherlands.
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Jeffrey R Johnson
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James E Haber
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Release 1.2