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Author Details

Martin J Humphries
University of Manchester
1983
286
86
Gloria M Sheynkman (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36804807A Nrf2-OSGIN1&2-HSP70 axis mediates cigarette smoke-induced endothelial detachment: implications for plaque erosion.Cardiovasc Res2023
37645762Extracellular vesicles stimulate smooth muscle cell migration by presenting collagen VI.bioRxiv2023
37460977Talin2 and KANK2 functionally interact to regulate microtubule dynamics, paclitaxel sensitivity and cell migration in the MDA-MB-435S melanoma cell line.Cell Mol Biol Lett2023
37455012Lineage Plasticity in SCLC Generates Non-Neuroendocrine Cells Primed for Vasculogenic Mimicry.J Thorac Oncol2023
37197981Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest.Life Sci Alliance2023
34518665A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids.Nat Mater2022
35405272Pancreatic ductal adenocarcinoma cells employ integrin α6β4 to form hemidesmosomes and regulate cell proliferation.Matrix Biol2022
36410791The βI domain promotes active β1 integrin clustering into mature adhesion sites.Life Sci Alliance2022
33309958KANK family proteins in cancer.Int J Biochem Cell Biol2021
34977030The Tongue Squamous Carcinoma Cell Line Cal27 Primarily Employs Integrin α6β4-Containing Type II Hemidesmosomes for Adhesion Which Contribute to Anticancer Drug Sensitivity.Front Cell Dev Biol2021
34239043A SNAI2-PEAK1-INHBA stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting subpopulations of tumor cells positive for antiapoptotic and stress signaling markers.Oncogene2021
34239032FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress.Sci Rep2021
34118235Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1.J Biol Chem2021
34049963Identification of an Altered Matrix Signature in Kidney Aging and Disease.J Am Soc Nephrol2021
32195252KANK2 Links αVβ5 Focal Adhesions to Microtubules and Regulates Sensitivity to Microtubule Poisons and Cell Migration.Front Cell Dev Biol2020
33458251Global proteomic analysis of insulin receptor interactors in glomerular podocytes.Wellcome Open Res2020
33077910ER-resident oxidoreductases are glycosylated and trafficked to the cell surface to promote matrix degradation by tumour cells.Nat Cell Biol2020
32833344Multiplexed Proximity Biotinylation Coupled to Mass Spectrometry for Defining Integrin Adhesion Complexes.Curr Protoc Cell Biol2020
32679769Integrin Crosstalk Contributes to the Complexity of Signalling and Unpredictable Cancer Cell Fates.Cancers (Basel)2020
32585685Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation.J Cell Biol2020
32147508Basement membrane ligands initiate distinct signalling networks to direct cell shape.Matrix Biol2020
31076511β1 integrin is a sensor of blood flow direction.J Cell Sci2019
30195153Signal transduction via integrin adhesion complexes.Curr Opin Cell Biol2019
31554981Multivalent anions as universal latent electron donors.Nature2019
31208994Clathrin-containing adhesion complexes.J Cell Biol2019
31431178Connections between the cell cycle, cell adhesion and the cytoskeleton.Philos Trans R Soc Lond B Biol Sci2019
31253831Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking.Nat Commun2019
30361699Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis.Nat Cell Biol2018
29930204Cell adhesion is regulated by CDK1 during the cell cycle.J Cell Biol2018
27553508Proteomic definitions of basement membrane composition in health and disease.Matrix Biol2017
28122868Conformational equilibria and intrinsic affinities define integrin activation.EMBO J2017
28394455Flexible Blade-Coated Multicolor Polymer Light-Emitting Diodes for Optoelectronic Sensors.Adv Mater2017
28979067Use of <i>N</i>-methyliminodiacetic acid boronate esters in suzuki-miyaura cross-coupling polymerizations of triarylamine and fluorene monomers.J Polym Sci A Polym Chem2017
28730483Characterization of the Phospho-Adhesome by Mass Spectrometry-Based Proteomics.Methods Mol Biol2017
28783304Post-polymerization C-H Borylation of Donor-Acceptor Materials Gives Highly Efficient Solid State Near-Infrared Emitters for Near-IR-OLEDs and Effective Biological Imaging.ACS Appl Mater Interfaces2017
28775156The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex.J Cell Sci2017
26147903Proteomic analysis of integrin-associated complexes from mesenchymal stem cells.Proteomics Clin Appl2016
26515553Mechanosensitivity of integrin adhesion complexes: role of the consensus adhesome.Exp Cell Res2016
27876801PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis.Nat Commun2016
27799358The integrin adhesome network at a glance.J Cell Sci2016
27317747Relating conformation to function in integrin α5β1.Proc Natl Acad Sci U S A2016
27460768Highly Emissive Far Red/Near-IR Fluorophores Based on Borylated Fluorene-Benzothiadiazole Donor-Acceptor Materials.Chemistry2016
27434228Allosteric Regulation of Fibronectin/α5β1 Interaction by Fibronectin-Binding MSCRAMMs.PLoS One2016
27484800Ligand-induced Epitope Masking: DISSOCIATION OF INTEGRIN α5β1-FIBRONECTIN COMPLEXES ONLY BY MONOCLONAL ANTIBODIES WITH AN ALLOSTERIC MODE OF ACTION.J Biol Chem2016
26833789Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition.J Cell Biol2016
25609142A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting.Nat Commun2015
29142733Enhancing electron affinity and tuning band gap in donor-acceptor organic semiconductors by benzothiadiazole directed C-H borylation.Chem Sci2015
26479319Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly.Nat Cell Biol2015
25896609Genetic Background is a Key Determinant of Glomerular Extracellular Matrix Composition and Organization.J Am Soc Nephrol2015
25824971Emerging properties of adhesion complexes: what are they and what do they do?Trends Cell Biol2015
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Collaborators

Maddy Parsons
Co-authored papers 6
Susan A Weston
Mayo Clinic
Co-authored papers 5
Andy Brass
Co-authored papers 5
John D Whittard
Co-authored papers 2
Julie Huxley-Jones
University of Manchester
Co-authored papers 2
Richard W Farndale
Co-authored papers 2
Peter Libby
Co-authored papers 1
Melike Lakadamyali
Center for Engineering Mechanobiology, University of Pennsylvania
Co-authored papers 1
Costantino Pitzalis
Co-authored papers 1
Erin D Jeffery
Agenus Inc, American Society for Mass Spectrometry, Hartwick College, Human Proteome Organisation, Large Scale Biology Corp, University of Virginia
Co-authored papers 1
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 1
Olivier Pertz
Co-authored papers 1
Paul C Driscoll
The Francis Crick Institute
Co-authored papers 1
Sharon J Pitteri
Stanford University
Co-authored papers 1
Nicholas W Chavkin
University of Virginia School of Medicine
Co-authored papers 1
Hema Vasavada
Cardiovascular Research Center, Yale University School of Medicine
Co-authored papers 1
Kristopher K Frese
Cancer Research UK Manchester Institute, University of Manchester
Co-authored papers 1
Sylvie Ricard-Blum
ICBMS UMR CNRS 5246, University Lyon 1
Co-authored papers 1
Yan Ting Shue
Stanford University
Co-authored papers 1
Jens G Lohr
Co-authored papers 1
Magnus H????k
Texas A&M Health Science Center Institute of Biosciences and Technology
Co-authored papers 1
Marko Salmi
Co-authored papers 1
Gloria M Sheynkman (CM4AI)
University of Virginia
Co-authored papers 1
Bipul R Acharya
Berne Cardiovascular Research Center, University of Virginia School of Medicine
Co-authored papers 1
Alison H Goodall
Co-authored papers 1
Moin A Saleem
Co-authored papers 1
David I Stuart
University of Oxford
Co-authored papers 1
Jonathan A Kelber
Co-authored papers 1
Gael Genet
University of Virginia School of Medicine
Co-authored papers 1
Olli Kallioniemi
Karolinska Institute
Co-authored papers 1
Release 1.2