Author details

Full Name

Kevin A Janes

Affiliation

University of Virginia

ORCID

Career Start Year

2001

Papers

H Index

Expertise

CM4AI Collaborator

Nevan J Krogan (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37163037	A genetic mosaic mouse model illuminates the pre-malignant progression of basal-like breast cancer.	bioRxiv	2023
37503057	Proteome-wide copy-number estimation from transcriptomics.	bioRxiv	2023
37055441	Nucleocytoplasmic transport of active HER2 causes fractional escape from the DCIS-like state.	Nat Commun	2023
37207276	Dichotomous ovarian cancer-initiating potential of Pax8+ cells revealed by a mouse genetic mosaic model.	iScience	2023
37131653	Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes.	bioRxiv	2023
37473730	Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition.	Cell Syst	2023
36549272	How can systems approaches help us understand and treat infectious disease?	Cell Syst	2022
33243834	A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism.	J Biol Chem	2021
33531375	Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments.	Cancer Res	2021
33531372	Premalignant Oligodendrocyte Precursor Cells Stall in a Heterogeneous State of Replication Stress Prior to Gliomagenesis.	Cancer Res	2021
33531373	Pan-Cancer Drivers Are Recurrent Transcriptional Regulatory Heterogeneities in Early-Stage Luminal Breast Cancer.	Cancer Res	2021
34806049	Simulating coxsackievirus B3 infection with an accessible computational model of its complete kinetics.	STAR Protoc	2021
34591839	Ten simple rules for being a faculty advocate of first-year graduate students.	PLoS Comput Biol	2021
32291314	Sporadic activation of an oxidative stress-dependent NRF2-p53 signaling network in breast epithelial spheroids and premalignancies.	Sci Signal	2020
31992582	Fragile epitopes-Antibody's guess is as good as yours.	Sci Signal	2020
30289437	CIRCOAST: a statistical hypothesis test for cellular colocalization with network structures.	Bioinformatics	2019
31873087	Robust latent-variable interpretation of in vivo regression models by nested resampling.	Sci Rep	2019
31857650	An ultrasensitive fiveplex activity assay for cellular kinases.	Sci Rep	2019
30032263	CIRCOAST: a statistical hypothesis test for cellular colocalization with network structures.	Bioinformatics	2019
30894605	In situ 10-cell RNA sequencing in tissue and tumor biopsy samples.	Sci Rep	2019
29593296	Automated brightfield morphometry of 3D organoid populations by OrganoSeg.	Sci Rep	2018
28590470	An engineering design approach to systems biology.	Integr Biol (Camb)	2017
28174228	Profiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes.	Mol Cell Proteomics	2017
29104075	Corrigendum to: "Small Molecule Inhibitor of CBFÎ²-RUNX Binding for RUNX Transcription Factor Driven Cancers" [EBioMedicine 8 (2016) 117-131].	EBioMedicine	2017
29161592	Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer.	Dev Cell	2017
27042975	Single-cell states versus single-cell atlases - two classes of heterogeneity that differ in meaning and method.	Curr Opin Biotechnol	2016
27965578	Computational Models of Reactive Oxygen Species as Metabolic Byproducts and Signal-Transduction Modulators.	Front Pharmacol	2016
27428424	Small Molecule Inhibitor of CBFÎ²-RUNX Binding for RUNX Transcription Factor Driven Cancers.	EBioMedicine	2016
27273097	TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors.	Sci Signal	2016
27273095	Science Signaling Podcast for 7 June 2016: Modeling signal integration.	Sci Signal	2016
26942229	Network Architecture Predisposes an Enzyme to Either Pharmacologic or Genetic Targeting.	Cell Syst	2016
25852189	An analysis of critical factors for quantitative immunoblotting.	Sci Signal	2015
26687346	Cell-to-Cell Transcript Variability: Seeing Signal in the Noise.	Cell	2015
24449900	Parameterizing cell-to-cell regulatory heterogeneities via stochastic transcriptional profiles.	Proc Natl Acad Sci U S A	2014
25145695	Bringing systems biology to cancer, immunology and infectious disease.	Genome Biol	2014
24956151	Non-genetic heterogeneity caused by differential single-cell adhesion.	Cell Cycle	2014
24658685	A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies.	Nat Cell Biol	2014
23332156	An ERK-p38 subnetwork coordinates host cell apoptosis and necrosis during coxsackievirus B3 infection.	Cell Host Microbe	2013
23921087	Simultaneous profiling of 194 distinct receptor transcripts in human cells.	Sci Signal	2013
23720376	Models of signalling networks - what cell biologists can gain from them and give to them.	J Cell Sci	2013
23233447	A high-throughput assay for phosphoprotein-specific phosphatase activity in cellular extracts.	Mol Cell Proteomics	2013
23306461	Stochastic profiling of transcriptional regulatory heterogeneities in tissues, tumors and cultured cells.	Nat Protoc	2013
21898857	Normal morphogenesis of epithelial tissues and progression of epithelial tumors.	Wiley Interdiscip Rev Syst Biol Med	2012
22871687	Modeling the latent dimensions of multivariate signaling datasets.	Phys Biol	2012
22476894	Multiscale models of cell signaling.	Ann Biomed Eng	2012
21873240	Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression.	Proc Natl Acad Sci U S A	2011
22024923	RUNX1 and its understudied role in breast cancer.	Cell Cycle	2011
20228812	Identifying single-cell molecular programs by stochastic profiling.	Nat Methods	2010
20833815	Pairwise network mechanisms in the host signaling response to coxsackievirus B3 infection.	Proc Natl Acad Sci U S A	2010
20622836	Paring down signaling complexity.	Nat Biotechnol	2010

1 - 50 of 67

Aurelien Dugourd

Institute of Experimental Medicine and Systems Biology, RWTH Aachen University

Career Start Year 2016

Number of shared co-authors 2

Genevieve L Stein-O'Brien

Johns Hopkins School of Medicine

Career Start Year 2014

Number of shared co-authors 0

David L Gibbs

Institute for Systems Biology

Career Start Year 2013

Number of shared co-authors 0

Elana J Fertig

Johns Hopkins University School of Medicine

Career Start Year 2010

Number of shared co-authors 0

Quy Nguyen

University of California irvine

Career Start Year 2009

Number of shared co-authors 1

Neda Bagheri

University of Washington

Career Start Year 2007

Number of shared co-authors 1

Marc R Birtwistle

Clemson University.

Career Start Year 2007

Number of shared co-authors 3

Armand Bankhead

Rogel Cancer Center, University of Michigan ann arbor

Career Start Year 2005

Number of shared co-authors 0

Jacob Stewart-Ornstein

Hillman Cancer Center, University of Pittsburgh School of Medicine

Career Start Year 2005

Number of shared co-authors 1

Bernd Bodenmiller

University of Zurich

Career Start Year 2005

Number of shared co-authors 3

Laura M Heiser

Oregon Health Sciences University

Career Start Year 2005

Number of shared co-authors 1

Jessica C Mar

Australian Institute for Bioengineering and Nanotechnology, University of Queensland

Career Start Year 2005

Number of shared co-authors 1

Julio Saez-Rodriguez

Institute of Computational Biomedicine, Heidelberg University

Career Start Year 2004

Number of shared co-authors 6

Efthymios Motakis

Yong Loo Lin School of Medicine, National University of Singapore

Career Start Year 2004

Number of shared co-authors 1

Terence P Speed

Walter and Eliza Hall Institute of Medical Research

Career Start Year 2003

Number of shared co-authors 0

Ken S Lau

Vanderbilt University School of Medicine

Career Start Year 2003

Number of shared co-authors 1

Hugh D Mitchell

Pacific Northwest National Laboratory (PNNL)

Career Start Year 2002

Number of shared co-authors 0

Ilya Shmulevich

Institute for Systems Biology

Career Start Year 2001

Number of shared co-authors 0

Lani F Wu

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 2001

Number of shared co-authors 1

Steven J Altschuler

Department of Pharmaceutical Chemistry, University of California san francisco

Career Start Year 2001

Number of shared co-authors 1

Jean Yee Hwa Yang

The University of Sydney

Career Start Year 2001

Number of shared co-authors 0

Mariano J Alvarez

Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center

Career Start Year 2000

Number of shared co-authors 1

Dana Pe'er

Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center

Career Start Year 2000

Number of shared co-authors 5

Roland Eils

Berlin Institute of Health (BIH) and Charite

Career Start Year 1995

Number of shared co-authors 2

Andrea Califano

Columbia University

Career Start Year 1993

Number of shared co-authors 4

Zolt??n N Oltvai

University of Rochester

Career Start Year 1991

Number of shared co-authors 0

Pablo Tamayo

University of California San Diego

Career Start Year 1988

Number of shared co-authors 0

Aviv Regev

Broad Institute of MIT and Harvard

Career Start Year 1987

Number of shared co-authors 2

Garry P Nolan

Stanford University School of Medicine

Career Start Year 1985

Number of shared co-authors 4

Yuval Kluger

Yale University School of Medicine

Career Start Year 1984

Number of shared co-authors 1

row(s) 1 - 30 of 30

Douglas A Lauffenburger

Massachusetts Institute of Technology

Co-authored papers 14

Peter K Sorger

Co-authored papers 6

Joan S Brugge

Co-authored papers 3

Mazhar Adli

Co-authored papers 2

Mahmut Parlak

University of Virginia

Co-authored papers 2

Jason A Papin

University of Virginia

Co-authored papers 2

Hans Clevers

Princess Maxima Center for Pediatric Oncology

Co-authored papers 1

Rebecca C Fry

Co-authored papers 1

Naeha Subramanian

Institute for Systems Biology

Co-authored papers 1

Martin S Tallman

Memorial Sloan-Kettering Cancer Center

Co-authored papers 1

Ali Bashashati

University of British Columbia

Co-authored papers 1

Nevan J Krogan (CM4AI)

University of California San Francisco

Co-authored papers 1

Shirit Einav

Stanford University School of Medicine

Co-authored papers 1

Francine E Garrett-Bakelman

University of Virginia

Co-authored papers 1

Jason H Yang

Rutgers New Jersey Medical School

Co-authored papers 1

Ronald N Germain

National Institute of Allergy and Infectious Diseases, National Institutes of Health

Co-authored papers 1

Jeffrey J Saucerman

University of Virginia

Co-authored papers 1

David de Graaf

Syntimmune Inc.

Co-authored papers 1

Matthew D Hirschey

Duke Molecular Physiology Institute, Duke University School of Medicine

Co-authored papers 1

Anna Kuchina

University of Washington

Co-authored papers 1

Michael J Muehlbauer

Duke University School of Medicine

Co-authored papers 1

James R Bain

Duke University Medical Center

Co-authored papers 1

Margaret E Wierman

Co-authored papers 1

Fabian J Theis

Technical University of Munich

Co-authored papers 1

Gerard J Ostheimer

Co-authored papers 1

Mehdi Bouhaddou

J. David Gladstone Institutes

Co-authored papers 1

Suna Onengut-Gumuscu

Co-authored papers 1

David L Brautigan

Co-authored papers 1

Bree B Aldridge

Tufts University School of Engineering

Co-authored papers 1

1 - 29

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