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Author Details
Full Name
David Neuhaus
Affiliation
Medical Research Council - Laboratory of Molecular Biology
ORCID
Career Start Year
1984
Papers
79
H Index
39
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37061529
Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
Nat Commun
2023
37326024
Updated protein domain annotation of the PARP protein family sheds new light on biological function.
Nucleic Acids Res
2023
34499853
Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure
2022
36113918
Zinc finger structure determination by NMR: Why zinc fingers can be a handful.
Prog Nucl Magn Reson Spectrosc
2022
33619271
RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination.
Nat Commun
2021
33511412
Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition.
Nucleic Acids Res
2021
32155440
Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev Cell
2020
32028527
HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation.
Nature
2020
33024112
Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29.
Nat Commun
2020
31582740
A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Nat Commun
2019
29667579
Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.
Elife
2018
28879231
Homeodomain-like DNA binding proteins control the haploid-to-diploid transition in <i>Dictyostelium</i>.
Sci Adv
2017
27247287
Fifty years of "Progress in NMR Spectroscopy" - An editorial from the present Editorial Board.
Prog Nucl Magn Reson Spectrosc
2016
25703931
¹¹³Cd⿿NMR experiments reveal an unusual metal cluster in the solution structure of the yeast splicing protein Bud31p.
Angew Chem Int Ed Engl
2015
26626479
Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1.
Mol Cell
2015
27478262
<sup>113</sup>Cdâ¿¿NMR Experiments Reveal an Unusual Metal Cluster in the Solution Structure of the Yeast Splicing Protein Bud31p.
Angew Chem Weinheim Bergstr Ger
2015
23871147
DNA-dependent SUMO modification of PARP-1.
DNA Repair (Amst)
2013
22560733
Structural basis for polyadenosine-RNA binding by Nab2 Zn fingers and its function in mRNA nuclear export.
Structure
2012
22955930
In support of the BMRB.
Nat Struct Mol Biol
2012
21262234
The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger.
J Mol Biol
2011
21666677
Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin.
Nat Struct Mol Biol
2011
21240272
Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.
Nat Struct Mol Biol
2011
20098424
Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat Struct Mol Biol
2010
19401465
Structural requirements for the ubiquitin-associated domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation THO complex component Hpr1 and nucleoporin FXFG repeats.
J Biol Chem
2009
18190927
Structure of the N-terminal Mlp1-binding domain of the Saccharomyces cerevisiae mRNA-binding protein, Nab2.
J Mol Biol
2008
18621724
Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif.
Proc Natl Acad Sci U S A
2008
17475778
Coordination of Hpr1 and ubiquitin binding by the UBA domain of the mRNA export factor Mex67.
Mol Biol Cell
2007
17609377
Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX.
Proc Natl Acad Sci U S A
2007
17355883
How the N-terminal domain of the OSCP subunit of bovine F1Fo-ATP synthase interacts with the N-terminal region of an alpha subunit.
J Mol Biol
2007
16545913
Identification of new differentiation inducing factors from Dictyostelium discoideum.
Biochim Biophys Acta
2006
15990112
Structural basis of the interaction between P-element somatic inhibitor and U1-70k essential for the alternative splicing of P-element transposase.
J Mol Biol
2005
15837933
Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors.
Proc Natl Acad Sci U S A
2005
16045926
Structure of the F1-binding domain of the stator of bovine F1Fo-ATPase and how it binds an alpha-subunit.
J Mol Biol
2005
15101973
Solution structure and domain architecture of the divisome protein FtsN.
Mol Microbiol
2004
15288782
Solution structure and DNA binding of the zinc-finger domain from DNA ligase IIIalpha.
J Mol Biol
2004
15312772
The structure and biochemical properties of the human spliceosomal protein U1C.
J Mol Biol
2004
15456745
Identification of a novel co-regulator interaction surface on the ligand binding domain of Nurr1 using NMR footprinting.
J Biol Chem
2004
15327958
Solution structure of subunit F(6) from the peripheral stalk region of ATP synthase from bovine heart mitochondria.
J Mol Biol
2004
12581645
Structural basis for the interaction between the Tap/NXF1 UBA domain and FG nucleoporins at 1A resolution.
J Mol Biol
2003
14556747
Solution NMR study of the interaction between NTF2 and nucleoporin FxFG repeats.
J Mol Biol
2003
11875519
Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1.
Nat Struct Biol
2002
11162601
Solution studies of chymotrypsin inhibitor-2 glutamine insertion mutants show no interglutamine interactions.
Biochem Biophys Res Commun
2001
11344319
HMG-D complexed to a bulge DNA: an NMR model.
Protein Sci
2001
11327770
Solution structure of a C-terminal coiled-coil domain from bovine IF(1): the inhibitor protein of F(1) ATPase.
J Mol Biol
2001
10742179
The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein.
Nat Struct Biol
2000
11080160
The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p.
EMBO J
2000
9566313
Determination of the NMR structure of the complex between U1A protein and its RNA polyadenylation inhibition element.
J Biomol NMR
1998
9878374
Solution structure of the motile major sperm protein (MSP) of Ascaris suum - evidence for two manganese binding sites and the possible role of divalent cations in filament formation.
J Mol Biol
1998
9664658
Amoeboid motility without actin: insights into the molecular mechanism of locomotion using the major sperm protein (MSP) of nematodes.
Biol Bull
1998
9312034
Structural basis of the RNA-binding specificity of human U1A protein.
EMBO J
1997
1 - 50 of 79
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