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Author Details
Full Name
Stephen A Migueles
Affiliation
National Institute of Allergy and Infectious Diseases, National Institutes of Health
ORCID
Career Start Year
1998
Papers
82
H Index
44
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37450602
An open label randomized controlled trial of atorvastatin versus aspirin in elite controllers and antiretroviral-treated people with HIV.
AIDS
2023
38096385
HIV vaccines induce CD8<sup>+</sup> T cells with low antigen receptor sensitivity.
Science
2023
35041523
Differential Expression of CREM/ICER Isoforms Is Associated with the Spontaneous Control of HIV Infection.
mBio
2022
33471124
Lost in Translation: Lack of CD4 Expression due to a Novel Genetic Defect.
J Infect Dis
2021
33536176
Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity <i>Ex Vivo and In Vivo</i>.
J Virol
2021
33529172
A replication-competent adenovirus-vectored influenza vaccine induces durable systemic and mucosal immunity.
J Clin Invest
2021
34506540
The impact of the 2014 Ebola epidemic on HIV disease burden and outcomes in Liberia West Africa.
PLoS One
2021
34228640
Naive infection predicts reservoir diversity and is a formidable hurdle to HIV eradication.
JCI Insight
2021
32907983
Antigenic Restimulation of Virus-Specific Memory CD8<sup>+</sup> T Cells Requires Days of Lytic Protein Accumulation for Maximal Cytotoxic Capacity.
J Virol
2020
30760706
Longitudinal HIV sequencing reveals reservoir expression leading to decay which is obscured by clonal expansion.
Nat Commun
2019
31830058
Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells.
PLoS One
2019
31415245
Adoptive lymphocyte transfer to an HIV-infected progressor from an elite controller.
JCI Insight
2019
31241541
ART in HIV-Positive Persons With Low Pretreatment Viremia: Results From the START Trial.
J Acquir Immune Defic Syndr
2019
31004012
Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine.
Sci Immunol
2019
29461980
Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.
J Clin Invest
2018
29875402
MAdCAM costimulation through Integrin-α4β7 promotes HIV replication.
Mucosal Immunol
2018
27453467
Multiple Origins of Virus Persistence during Natural Control of HIV Infection.
Cell
2016
26663780
IL-12-Dependent Cytomegalovirus-Specific CD4+ T Cell Proliferation, T-bet Induction, and Effector Multifunction during Primary Infection Are Key Determinants for Early Immune Control.
J Immunol
2016
27851912
Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.
Immunity
2016
27760334
Class II-Restricted CD8s: New Lessons Violate Old Paradigms.
Immunity
2016
27630237
Monitoring Integration over Time Supports a Role for Cytotoxic T Lymphocytes and Ongoing Replication as Determinants of Reservoir Size.
J Virol
2016
25600384
Should all research subjects be treated the same?
Hastings Cent Rep
2015
26546609
Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.
J Immunol
2015
26537682
A Subset of CD4/CD8 Double-Negative T Cells Expresses HIV Proteins in Patients on Antiretroviral Therapy.
J Virol
2015
26702094
Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection.
Sci Transl Med
2015
25988888
Success and failure of the cellular immune response against HIV-1.
Nat Immunol
2015
25711322
Clinical and demographic factors associated with low viral load in early untreated HIV infection in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial.
HIV Med
2015
24227851
Increased sequence coverage through combined targeting of variant and conserved epitopes correlates with control of HIV replication.
J Virol
2014
26137533
CD8(+) T-cell Cytotoxic Capacity Associated with Human Immunodeficiency Virus-1 Control Can Be Mediated through Various Epitopes and Human Leukocyte Antigen Types.
EBioMedicine
2014
26023356
HIV-1 Treated Patients with Undetectable Viral Loads have Lower Levels of Innate Immune Responses via Cytosolic DNA Sensing Systems Compared with Healthy Uninfected Controls.
J AIDS Clin Res
2014
25186731
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.
Nature
2014
24554663
CD4+ memory stem cells are infected by HIV-1 in a manner regulated in part by SAMHD1 expression.
J Virol
2014
24185941
Evidence for innate immune system activation in HIV type 1-infected elite controllers.
J Infect Dis
2014
23468632
Cytotoxic capacity of SIV-specific CD8(+) T cells against primary autologous targets correlates with immune control in SIV-infected rhesus macaques.
PLoS Pathog
2013
23951263
Gag-positive reservoir cells are susceptible to HIV-specific cytotoxic T lymphocyte mediated clearance in vitro and can be detected in vivo [corrected].
PLoS One
2013
24030440
Isolation of human monoclonal antibodies from peripheral blood B cells.
Nat Protoc
2013
23661761
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Science
2013
22278241
HLA B*5701-positive long-term nonprogressors/elite controllers are not distinguished from progressors by the clonal composition of HIV-specific CD8+ T cells.
J Virol
2012
23014521
Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trials.
AIDS
2012
23151583
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody.
Nature
2012
22445844
Inhibitory Killer Immunoglobulin-like Receptors to self HLA-B and HLA-C ligands contribute differentially to Natural Killer cell functional potential in HIV infected slow progressors.
Clin Immunol
2012
22444629
Small molecules and big killers: the challenge of eliminating the latent HIV reservoir.
Immunity
2012
22490332
Comprehensive analysis of unique cases with extraordinary control over HIV replication.
Blood
2012
22674985
Antibody-dependent cellular cytotoxicity against primary HIV-infected CD4+ T cells is directly associated with the magnitude of surface IgG binding.
J Virol
2012
21399496
Qualitative features of the HIV-specific CD8+ T-cell response associated with immunologic control.
Curr Opin HIV AIDS
2011
21841160
Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand.
Blood
2011
21921725
HIV/HCV-coinfected natural viral suppressors have better virologic responses to PEG-IFN and ribavirin than ARV-treated HIV/HCV patients.
J Acquir Immune Defic Syndr
2011
21383976
Trivalent adenovirus type 5 HIV recombinant vaccine primes for modest cytotoxic capacity that is greatest in humans with protective HLA class I alleles.
PLoS Pathog
2011
21383972
Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART.
PLoS Pathog
2011
21471235
Receptor-ligand requirements for increased NK cell polyfunctional potential in slow progressors infected with HIV-1 coexpressing KIR3DL1*h/*y and HLA-B*57.
J Virol
2011
1 - 50 of 82
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