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Author Details

Patrick Auberger
Universite Cote d'Azur, INSERM U5
1982
215
55
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36375119BTG1 inactivation drives lymphomagenesis and promotes lymphoma dissemination through activation of BCAR1.Blood2023
37616262The Antioxidant TEMPOL Protects Human Hematopoietic Stem Cells From Culture-Mediated Loss of Functions.Stem Cells Transl Med2023
37143666The generation, activation, and polarization of monocyte-derived macrophages in human malignancies.Front Immunol2023
36585521High caspase 3 and vulnerability to dual BCL2 family inhibition define ETO2::GLIS2 pediatric leukemia.Leukemia2023
36711936MCB-613 exploits a collateral sensitivity in drug resistant <i>EGFR</i>-mutant non-small cell lung cancer through covalent inhibition of KEAP1.bioRxiv2023
36835566Caspase Inhibition Modulates Monocyte-Derived Macrophage Polarization in Damaged Tissues.Int J Mol Sci2023
36394159Real-life challenges using personalized prognostic scoring systems in acute myeloid leukemia.Cancer Med2023
34986346AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia.Cell Rep2022
35641638REDD1 is a gatekeeper of murine hematopoietic stem cell functions during stress responses.Leukemia2022
35668193P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia.Nat Cancer2022
35496477A new ChEMBL dataset for the similarity-based target fishing engine FastTargetPred: Annotation of an exhaustive list of linear tetrapeptides.Data Brief2022
34099492Dual Covalent Inhibition of PKM and IMPDH Targets Metabolism in Cutaneous Metastatic Melanoma.Cancer Res2021
33547392Plk1, upregulated by HIF-2, mediates metastasis and drug resistance of clear cell renal cell carcinoma.Commun Biol2021
33683342Heterogeneous NLRP3 inflammasome signature in circulating myeloid cells as a biomarker of COVID-19 severity.Blood Adv2021
33570629Real-life experience with CPX-351 and impact on the outcome of high-risk AML patients: a multicentric French cohort.Blood Adv2021
33790022Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor.Sci Transl Med2021
35251769Reprogramming monocyte-derived macrophages through caspase inhibition.Oncoimmunology2021
34520963Ultrasound-assisted one-pot three-component synthesis of new isoxazolines bearing sulfonamides and their evaluation against hematological malignancies.Ultrason Sonochem2021
32160545ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.Cell Rep2020
31990086Clonal selection in therapy-related myelodysplastic syndromes and acute myeloid leukemia under azacitidine treatment.Eur J Haematol2020
32665699Retraction Note: LAMP2 expression dictates azacytidine response and prognosis in MDS/AML.Leukemia2020
32847013Drug Resistance in Hematological Malignancies.Int J Mol Sci2020
30571969Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice.J Invest Dermatol2019
31410218New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments.Theranostics2019
31623164Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies.Cells2019
30806567Azacitidine resistance caused by LAMP2 deficiency: a therapeutic window for the use of autophagy inhibitors in MDS/AML patients?Autophagy2019
30607021LAMP2 expression dictates azacytidine response and prognosis in MDS/AML.Leukemia2019
28914261RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia.Leukemia2018
30176265ZNF224 is a transcriptional repressor of AXL in chronic myeloid leukemia cells.Biochimie2018
30274374Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation.Int J Mol Sci2018
29703842Targeting the Proteasome-Associated Deubiquitinating Enzyme USP14 Impairs Melanoma Cell Survival and Overcomes Resistance to MAPK-Targeting Therapies.Mol Cancer Ther2018
29391601The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.Oncogene2018
29655981Modular synthesis of new C-aryl-nucleosides and their anti-CML activity.Bioorg Med Chem Lett2018
29321503IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.Sci Rep2018
27956388Autophagy, a key mechanism of oncogenesis and resistance in leukemia.Blood2017
28191887The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.Nat Med2017
28325600Synthesis and anti-cancer activities of new sulfonamides 4-substituted-triazolyl nucleosides.Bioorg Med Chem Lett2017
28094938In Vitro and in Vivo Evaluation of Fully Substituted (5-(3-Ethoxy-3-oxopropynyl)-4-(ethoxycarbonyl)-1,2,3-triazolyl-glycosides as Original Nucleoside Analogues to Circumvent Resistance in Myeloid Malignancies.J Med Chem2017
28367807[Autophagy, a key player in leukemogenesis and a therapeutic target in hematopoietic malignancies].Med Sci (Paris)2017
29423056Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia.Oncotarget2017
29541386ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines.Oncotarget2017
28983059Pro-inflammatory proteins S100A9 and tumor necrosis factor-α suppress erythropoietin elaboration in myelodysplastic syndromes.Haematologica2017
28514758BCL2L10 positive cells in bone marrow are an independent prognostic factor of azacitidine outcome in myelodysplastic syndrome and acute myeloid leukemia.Oncotarget2017
28850564CXCL7 is a predictive marker of sunitinib efficacy in clear cell renal cell carcinomas.Br J Cancer2017
27881579An miRNA-DNMT1 Axis Is Involved in Azacitidine Resistance and Predicts Survival in Higher-Risk Myelodysplastic Syndrome and Low Blast Count Acute Myeloid Leukemia.Clin Cancer Res2017
27027430Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death.Oncotarget2016
27816170[Nobel prizes in medicine 2016].Bull Cancer2016
27455953BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice.J Exp Med2016
27388216DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes.Diabetes2016
26799652Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Autophagy2016
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Collaborators

Arnaud Jacquel
Universite Cote d'Azur, INSERM U5
Co-authored papers 64
Alexandre Puissant
Universite de Paris, INSERM, CNRS
Co-authored papers 39
Thomas Cluzeau
Universite Nice Cote d'azur, CHU de Nice
Co-authored papers 23
Nina Fenouille
Universite Paris Cite, INSERM, CNRS
Co-authored papers 10
Lionel Ad??s
Assistance Publique des Hopitaux de Paris (AP-HP)
Co-authored papers 5
Paul Chaintreuil
Universite Cote d'Azur, Institut National de la Sante et de la Recherche Medicale
Co-authored papers 5
Gaetano Sodaro
Universite Paris Cite, INSERM, CNRS
Co-authored papers 4
Christopher F Bassil
Duke University School of Medicine Durham
Co-authored papers 4
Claude Preudhomme
Lille University Hospital, INSERM UMR-S7, CNRS UMR9020, Lille University.
Co-authored papers 3
Lina Benajiba
Universite de Paris, Inserm CIC 1427
Co-authored papers 3
Thomas J Begley
University at Albany
Co-authored papers 2
Ana Maria Cuervo
Albert Einstein College of Medicine
Co-authored papers 2
Laura Santambrogio
Weill Cornell School of Medicine
Co-authored papers 2
Ioannis P Nezis
University of Warwick
Co-authored papers 2
Stoyan Ivanov
Co-authored papers 2
Scott J Bultman
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Co-authored papers 2
Masashi Narita
Co-authored papers 2
Karin Przyklenk
Co-authored papers 2
Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 2
Svetlana Dokudovskaya
CNRS UMR9018, Institut Gustave Roussy, Universite Paris-Saclay
Co-authored papers 2
Hirotaka Watada
Co-authored papers 2
Sara Cherry
University of Pennsylvania
Co-authored papers 2
Carlos L??pez-Ot??n
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 2
Kris C Wood
Duke University
Co-authored papers 2
David Sulzer
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
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David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
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J. Wade Harper
Harvard Medical School
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Release 1.2