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Author Details

Alkes L Price
Broad Institute of MIT and Harvard
2003
136
74
PMIDPaper TitleJournal TitlePublished Year
37790574Distinct explanations underlie gene-environment interactions in the UK Biobank.medRxiv2024
37790574Distinct explanations underlie gene-environment interactions in the UK Biobank.medRxiv2024
36747789Systematically characterizing the roles of E3-ligase family members in inflammatory responses with massively parallel Perturb-seq.bioRxiv2023
37814053Age-dependent topic modeling of comorbidities in UK Biobank identifies disease subtypes with differential genetic risk.Nat Genet2023
37580597Modeling tissue co-regulation estimates tissue-specific contributions to disease.Nat Genet2023
36747789Systematically characterizing the roles of E3-ligase family members in inflammatory responses with massively parallel Perturb-seq.bioRxiv2023
37580597Modeling tissue co-regulation estimates tissue-specific contributions to disease.Nat Genet2023
37814053Age-dependent topic modeling of comorbidities in UK Biobank identifies disease subtypes with differential genetic risk.Nat Genet2023
36050550Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data.Nat Genet2022
36175791Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics.Nat Genet2022
35935918Incorporating family history of disease improves polygenic risk scores in diverse populations.Cell Genom2022
35545678Single-cell eQTL models reveal dynamic T cell state dependence of disease loci.Nature2022
36050550Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data.Nat Genet2022
35545678Single-cell eQTL models reveal dynamic T cell state dependence of disease loci.Nature2022
36175791Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics.Nat Genet2022
35935918Incorporating family history of disease improves polygenic risk scores in diverse populations.Cell Genom2022
33987664Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations.Hum Mol Genet2021
33686288Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS.Nat Genet2021
33987664Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations.Hum Mol Genet2021
33828297Genome-wide enhancer maps link risk variants to disease genes.Nature2021
34845454Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics.bioRxiv2021
33828297Genome-wide enhancer maps link risk variants to disease genes.Nature2021
33686288Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS.Nat Genet2021
34845454Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics.bioRxiv2021
32831138GBAT: a gene-based association test for robust detection of trans-gene regulation.Genome Biol2020
33257898Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements.Nat Genet2020
32943643Evaluating the informativeness of deep learning annotations for human complex diseases.Nat Commun2020
32831138GBAT: a gene-based association test for robust detection of trans-gene regulation.Genome Biol2020
33257898Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements.Nat Genet2020
32943643Evaluating the informativeness of deep learning annotations for human complex diseases.Nat Commun2020
30474154Estimating cross-population genetic correlations of causal effect sizes.Genet Epidemiol2019
31809749Genes with High Network Connectivity Are Enriched for Disease Heritability.Am J Hum Genet2019
30595370Leveraging Polygenic Functional Enrichment to Improve GWAS Power.Am J Hum Genet2019
30487263Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control.Diabetes2019
30474154Estimating cross-population genetic correlations of causal effect sizes.Genet Epidemiol2019
31492842Functional disease architectures reveal unique biological role of transposable elements.Nat Commun2019
31273336Author Correction: Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.Nat Genet2019
30683880Shared heritability and functional enrichment across six solid cancers.Nat Commun2019
31402091Extreme Polygenicity of Complex Traits Is Explained by Negative Selection.Am J Hum Genet2019
31006511IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors.Am J Hum Genet2019
31548585Publisher Correction: Shared heritability and functional enrichment across six solid cancers.Nat Commun2019
30770844Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection.Nat Commun2019
31809749Genes with High Network Connectivity Are Enriched for Disease Heritability.Am J Hum Genet2019
31273336Author Correction: Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.Nat Genet2019
31492842Functional disease architectures reveal unique biological role of transposable elements.Nat Commun2019
31548585Publisher Correction: Shared heritability and functional enrichment across six solid cancers.Nat Commun2019
31402091Extreme Polygenicity of Complex Traits Is Explained by Negative Selection.Am J Hum Genet2019
30770844Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection.Nat Commun2019
31006511IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors.Am J Hum Genet2019
30683880Shared heritability and functional enrichment across six solid cancers.Nat Commun2019
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Hilary K Finucane
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David Reich
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Bogdan Pasaniuc
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Benjamin M Neale
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Noah Zaitlen
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Mark J Daly
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Jerome I Rotter
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Steven A McCarroll
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Arti Tandon
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Patrick F Sullivan
University of North Carolina at Chapel Hill
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Peter M Visscher
Co-authored papers 8
Sonja I Berndt
Co-authored papers 8
Giulio Genovese
Co-authored papers 8
Simon Myers
University of Oxford
Co-authored papers 8
Stephan Ripke
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 8
Albert V Smith
University of Michigan School of Public Health ann arbor
Co-authored papers 7
Release 1.2