Author details

Full Name

Theodore Nicolaides

Affiliation

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36993741	Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses.	Res Sq	2023
35481313	A Holistic Review on the Current and Future Status of Biology-Driven and Broad-Spectrum Therapeutic Options for Medulloblastoma.		2022
36274161	Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma.	Acta Neuropathol Commun	2022
34873529	Tumor-Educated Platelets: A Review of Current and Potential Applications in Solid Tumors.		2021
33945292	Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance.	J Clin Oncol	2021
33073916	Radiologic response to MEK inhibition in a patient with a WNT-activated craniopharyngioma.	Pediatric Blood and Cancer	2021
34433654	Deconvoluting Mechanisms of Acquired Resistance to RAF Inhibitors in BRAF[V600E]-Mutant Human Glioma.	Clin Cancer Res	2021
34646647	A Novel Blood-Brain Barrier-Permeable Chemotherapeutic Agent for the Treatment of Glioblastoma.		2021
32603316	Everolimus improves the efficacy of dasatinib in PDGFRÎ±-driven glioma.	J Clin Invest	2020
31815884	Germline MUTYH Mutation in a Pediatric Cancer Survivor Developing a Secondary Malignancy.	J Pediatr Hematol Oncol	2020
32476174	Population Pharmacokinetics of Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E-Mutant Astrocytomas.	J Clin Pharmacol	2020
32594172	Exploring DNA Methylation for Prognosis and Analyzing the Tumor Microenvironment in Pleomorphic Xanthoastrocytoma.	J Neuropathol Exp Neurol	2020
32523649	Phase I study of vemurafenib in children with recurrent or progressive BRAF<sup>V600E</sup> mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002).	Oncotarget	2020
32678903	LSD1 inhibition in pHGG: the key to unleashing immunotherapy?	Neuro-Oncology	2020
31433983	Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness.	Cell Rep	2019
30397180	Cell Surface Notch Ligand DLL3 is a Therapeutic Target in Isocitrate Dehydrogenase-mutant Glioma.	Clin Cancer Res	2019
30051528	The genetic landscape of anaplastic pleomorphic xanthoastrocytoma.	Brain Pathol	2019
29435664	Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.	Acta Neuropathol	2018
28696243	Inhibiting 4EBP1 in Glioblastoma.	Clin Cancer Res	2018
30510874	Delayed Fluorodeoxyglucose Positron Emission Tomography Imaging in the Differentiation of Tumor Recurrence and Radiation Necrosis in Pediatric Central Nervous System Tumors: Case Report and Review of the Literature.		2018
30206764	Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience.	J Neurooncol	2018
29946497	Surveillance Screening in Li-Fraumeni Syndrome: Raising Awareness of False Positives.		2018
30563038	Evaluation of Three Morphologically Distinct Virus-Like Particles as Nanocarriers for Convection-Enhanced Drug Delivery to Glioblastoma.	Nanomaterials (Basel)	2018
28292440	A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma.	Cancer Cell	2017
28434113	Precision knockdown of EGFR gene expression using radio frequency electromagnetic energy.	J Neurooncol	2017
28727518	Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas.	J Clin Oncol	2017
28453743	Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.	Neuro Oncol	2017
28339824	A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study.	Neuro Oncol	2017
29487768	Suprasellar Germinoma Presenting with Slipped Capital Femoral Epiphysis: Case Report.	Cureus	2017
27282398	Pediatric high-grade glioma: biologically and clinically in need of new thinking.	Neuro Oncol	2017
27611946	Acquired resistance to BRAF inhibition in BRAFV600E mutant gliomas.	Oncotarget	2017
27848137	Combined BRAF<sup>V600E</sup> and MEK blockade for BRAF<sup>V600E</sup>-mutant gliomas.	J Neurooncol	2017
27683733	Pediatric low-grade gliomas: implications of the biologic era.	Neuro Oncol	2017
28304223	Metastatic clival chordoma: a case report of multiple extraneural metastases following resection and proton beam radiotherapy in a 5-year old boy.	J Neurosurg Pediatr	2017
27713119	Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model.	Oncotarget	2016
27382528	Bromodomain Inhibitor Review: Bromodomain and Extra-terminal Family Protein Inhibitors as a Potential New Therapy in Central Nervous System Tumors.		2016
26782702	Erratum to: Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma.	J Neurooncol	2016
26384810	Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma.	J Neurooncol	2016
27624885	Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation.	Acta Neuropathol	2016
27960086	Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.	Cancer Cell	2016
26573800	Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells.	Cancer Res	2015
25882982	Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.	Lancet Oncol	2015
25720745	High rate of concurrent BRAF-KIAA1549 gene fusion and 1p deletion in disseminated oligodendroglioma-like leptomeningeal neoplasms (DOLN).	Acta Neuropathol	2015
26525348	Targeted Therapy for MAPK Alterations in Pediatric Gliomas.		2015
26251821	Metastatic Diffuse Intrinsic Pontine Glioma to the Peritoneal Cavity Via Ventriculoperitoneal Shunt: Case Report and Literature Review.	Journal of Neurological Surgery Reports	2015
26023796	EGFR blockade prevents glioma escape from BRAFV600E targeted therapy.	Oncotarget	2015
25189788	Pure germinomas of the central nervous system: treatment strategies and outcomes.	J Neurooncol	2014
25313012	NT113, a pan-ERBB inhibitor with high brain penetrance, inhibits the growth of glioblastoma xenografts with EGFR amplification.	Mol Cancer Ther	2014
23666401	Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children.	Childs Nerv Syst	2013
22983601	Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment.	J Neurooncol	2012