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Author Details

Justin M Kollman
University of Washington
1999
68
28
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36709625Greater than the sum of parts: Mechanisms of metabolic regulation by enzyme filaments.Curr Opin Struct Biol2023
37790411Light-sensitive phosphorylation regulates enzyme activity and filament assembly of human IMPDH1 retinal splice variants.bioRxiv2023
37693530<i>Toxoplasma gondii</i> actin filaments are tuned for rapid disassembly and turnover.bioRxiv2023
36993700Point mutations in IMPDH2 which cause early-onset neurodevelopmental disorders disrupt enzyme regulation and filament structure.bioRxiv2023
37414152Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.J Biol Chem2023
37333359Blueprinting expandable nanomaterials with standardized protein building blocks.bioRxiv2023
36747094Human PRPS1 filaments stabilize allosteric sites to regulate activity.Nat Struct Mol Biol2023
34813793A highly conserved zebrafish IMPDH retinal isoform produces the majority of guanine and forms dynamic protein filaments in photoreceptor cells.J Biol Chem2022
35482847The Giardia ventrolateral flange is a lamellar membrane protrusion that supports attachment.PLoS Pathog2022
35446645Computational design of mechanically coupled axle-rotor protein assemblies.Science2022
36191189SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.Proc Natl Acad Sci U S A2022
35191957IMPDH dysregulation in disease: a mini review.Biochem Soc Trans2022
35013599IMPDH1 retinal variants control filament architecture to tune allosteric regulation.Nat Struct Mol Biol2022
33408408Design of biologically active binary protein 2D materials.Nature2021
33654323Author Correction: Design of biologically active binary protein 2D materials.Nature2021
33589814BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.Nat Struct Mol Biol2021
33661302Multimeric antibodies from antigen-specific human IgM+ memory B cells restrict Plasmodium parasites.J Exp Med2021
34734801Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.Elife2021
34583994Structural basis for isoform-specific inhibition of human CTPS1.Proc Natl Acad Sci U S A2021
34320407Selective activation of PFKL suppresses the phagocytic oxidative burst.Cell2021
32424337Lysogenic host-virus interactions in SAR11 marine bacteria.Nat Microbiol2020
31999252Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation.Elife2020
31873303Coupled structural transitions enable highly cooperative regulation of human CTPS2 filaments.Nat Struct Mol Biol2020
32108112Polymerization in the actin ATPase clan regulates hexokinase activity in yeast.Science2020
32580972CTP synthase polymerization in germline cells of the developing Drosophila egg supports egg production.Biol Open2020
32848250Computational design of transmembrane pores.Nature2020
32417394Filament formation by metabolic enzymes-A new twist on regulation.Curr Opin Cell Biol2020
32245816Modular repeat protein sculpting using rigid helical junctions.Proc Natl Acad Sci U S A2020
32463766Freedom of assembly: metabolic enzymes come together.Mol Biol Cell2020
30638443The Acinetobacter baumannii Mla system and glycerophospholipid transport to the outer membrane.Elife2019
31050411Self-Assembling 2D Arrays with de Novo Protein Building Blocks.J Am Chem Soc2019
29440491Cryo-EM structure of the bacterial actin AlfA reveals unique assembly and ATP-binding interactions and the absence of a conserved subdomain.Proc Natl Acad Sci U S A2018
30154209T cell activation triggers reversible inosine-5'-monophosphate dehydrogenase assembly.J Cell Sci2018
30245157The Structure and Dynamics of C. elegans Tubulin Reveals the Mechanistic Basis of Microtubule Growth.Dev Cell2018
30409885De novo design of self-assembling helical protein filaments.Science2018
27391173Structure of the magnetosome-associated actin-like MamK filament at subnanometer resolution.Protein Sci2017
28459447Human CTP synthase filament structure reveals the active enzyme conformation.Nat Struct Mol Biol2017
28254381Vitrification after multiple rounds of sample application and blotting improves particle density on cryo-electron microscopy grids.J Struct Biol2017
28263957The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation.Nat Cell Biol2017
28490633Single-particle electron microscopy structure of UDP-glucose:glycoprotein glucosyltransferase suggests a selectivity mechanism for misfolded proteins.J Biol Chem2017
28646105The glycolytic enzyme phosphofructokinase-1 assembles into filaments.J Cell Biol2017
28561052Corrigendum: The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation.Nat Cell Biol2017
28794265Reconstituted IMPDH polymers accommodate both catalytically active and inactive conformations.Mol Biol Cell2017
26968363Structure of γ-tubulin small complex based on a cryo-EM map, chemical cross-links, and a remotely related structure.J Struct Biol2016
27571563Inhibition of Escherichia coli CTP Synthetase by NADH and Other Nicotinamides and Their Mutual Interactions with CTP and GTP.Biochemistry2016
25599398Ring closure activates yeast γTuRC for species-specific microtubule nucleation.Nat Struct Mol Biol2015
25971801Interaction of CK1δ with γTuSC ensures proper microtubule assembly and spindle positioning.Mol Biol Cell2015
24481252Accessory factors promote AlfA-dependent plasmid segregation by regulating filament nucleation, disassembly, and bundling.Proc Natl Acad Sci U S A2014
25030911Large-scale filament formation inhibits the activity of CTP synthetase.Elife2014
23204522The bacterial actin MamK: in vitro assembly behavior and filament architecture.J Biol Chem2013
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Collaborators

David A Agard
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 12
David Baker
University of Washington
Co-authored papers 8
Frank DiMaio
University of Washington
Co-authored papers 6
Trisha N Davis
University of Washington
Co-authored papers 5
Alex Zelter
University of Washington
Co-authored papers 5
R Dyche Mullins
University of California San Francisco, USA Howard Hughes Medical Institute
Co-authored papers 4
Zemer Gitai
Princeton University
Co-authored papers 3
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 2
Michelle Moritz
University of California san francisco
Co-authored papers 2
Neil P King
Co-authored papers 2
David Veesler
Co-authored papers 2
Charles H Greenberg
University of California San Francisco
Co-authored papers 2
Miles Sasha Dickinson
University of Washington
Co-authored papers 2
Milton H Saier
University of California at San Diego
Co-authored papers 2
Andrew S Lyon
University of California san francisco
Co-authored papers 1
Michael J MacCoss
University of Washington
Co-authored papers 1
Gary J Brouhard
McGill University
Co-authored papers 1
Gydo C P van Zundert
Utrecht University
Co-authored papers 1
Torsten Wittmann
University of California san francisco
Co-authored papers 1
Mark Winey
University of California davis
Co-authored papers 1
Jos?? Jes??s Fern??ndez
National Center for Biotechnology, Spanish National Research Council
Co-authored papers 1
John V Kilmartin
Medical Research Council Laboratory of Molecular Biology
Co-authored papers 1
Diane L Barber
University of California San Francisco
Co-authored papers 1
William A Catterall
Co-authored papers 1
Luke M Rice
the University of Texas Southwestern Medical Center
Co-authored papers 1
Eric G D Muller
University of Washington
Co-authored papers 1
Xuemei Han
Co-authored papers 1
Alexandra C Walls
Co-authored papers 1
Bita Shahrvini
University of California Davis
Co-authored papers 1
John R Yates
TheScripps Research Institute
Co-authored papers 1
Release 1.2