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Author Details

James L Wynn
University of Florida, College of Medicine
2006
93
34
PMIDPaper TitleJournal TitlePublished Year
34674193Contribution of Concurrent Comorbidities to Sepsis-Related Mortality in Preterm Infants ⿤32 Weeks of Gestation at an Academic Neonatal Intensive Care Network.Am J Perinatol2024
33971672Sepsis and Mortality Prediction in Very Low Birth Weight Infants: Analysis of HeRO and nSOFA.Am J Perinatol2023
37757759Evaluation of the Neonatal Sequential Organ Failure Assessment and Mortality Risk in Neonates with Early-Onset Infection.Neonatology2023
38051733Protocol for the development of a core outcome set for neonatal sepsis (NESCOS).PLoS One2023
34743180Neonatal sepsis definitions from randomised clinical trials.Pediatr Res2023
34550843Hourly Kinetics of Critical Organ Dysfunction in Extremely Preterm Infants.Am J Respir Crit Care Med2022
35704600The balance between protective and pathogenic immune responses to pneumonia in the neonatal lung is enforced by gut microbiota.Sci Transl Med2022
36512358Frequency of Acute Kidney Injury and Association With Mortality Among Extremely Preterm Infants.JAMA Netw Open2022
35313308Evaluation of the Neonatal Sequential Organ Failure Assessment and Mortality Risk in Preterm Infants with Necrotizing Enterocolitis.Neonatology2022
34970683Scoring Systems for Organ Dysfunction and Multiple Organ Dysfunction: The PODIUM Consensus Conference.Pediatrics2022
34997225Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials.Pediatr Res2022
34970673Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary.Pediatrics2022
34970671Refining the Pediatric Multiple Organ Dysfunction Syndrome.Pediatrics2022
34612847Criteria for Pediatric Sepsis-A Systematic Review and Meta-Analysis by the Pediatric Sepsis Definition Taskforce.Crit Care Med2022
33122842Correction: Neonatal sepsis: need for consensus definition, collaboration and core outcomes.Pediatr Res2021
33712712Maximum vasoactive-inotropic score and mortality in extremely premature, extremely low birth weight infants.J Perinatol2021
33541918Absence of relationship between serum cortisol and critical illness in premature infants.Arch Dis Child Fetal Neonatal Ed2021
33538825Evaluation of the Neonatal Sequential Organ Failure Assessment and Mortality Risk in Preterm Infants With Late-Onset Infection.JAMA Netw Open2021
34022247Multicenter Validation of the Neonatal Sequential Organ Failure Assessment Score for Prognosis in the Neonatal Intensive Care Unit.J Pediatr2021
31394566A neonatal sequential organ failure assessment score predicts mortality to late-onset sepsis in preterm very low birth weight infants.Pediatr Res2020
32012200Cell-free hemoglobin increases inflammation, lung apoptosis, and microvascular permeability in murine polymicrobial sepsis.PLoS One2020
31977960Exploring Clinically-Relevant Experimental Models of Neonatal Shock and Necrotizing Enterocolitis.Shock2020
32376769BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis.Sci Transl Med2020
32396924Application of metabolomics to neonatal meningitis.Pediatr Res2020
32193517Neonatal sepsis: need for consensus definition, collaboration and core outcomes.Pediatr Res2020
30579470Early onset and hospital acquired neonatal sepsis associated with high mortality.J Pediatr2019
30836378Prolonged early antimicrobials in ELBWs: too much for too little.Pediatr Res2019
30741260A Controlled Mouse Model for Neonatal Polymicrobial Sepsis.J Vis Exp2019
29340570Name and Characteristics of National Institutes of Health R01-Funded Pediatric Physician-Scientists: Hope and Challenges for the Vanishing Pediatric Physician-Scientists.JAMA Pediatr2018
29808244Impact of toll-like receptor 4 stimulation on human neonatal neutrophil spontaneous migration, transcriptomics, and cytokine production.J Mol Med (Berl)2018
29904137Limited achievement of NIH research independence by pediatric K award recipients.Pediatr Res2018
30533615Complete Genome Sequence of the Multidrug-Resistant Neonatal Meningitis Escherichia coli Serotype O75:H5:K1 Strain mcjchv-1 (NMEC-O75).Microbiol Resour Announc2018
30305325Cutting Edge: IL-1α and Not IL-1β Drives IL-1R1-Dependent Neonatal Murine Sepsis Lethality.J Immunol2018
28419265Validation of the Sepsis MetaScore for Diagnosis of Neonatal Sepsis.J Pediatric Infect Dis Soc2018
29382648Why are preterm newborns at increased risk of infection?Arch Dis Child Fetal Neonatal Ed2018
29510382Enteral Feeding as an Adjunct to Hypothermia in Neonates with Hypoxic-Ischemic Encephalopathy.Neonatology2018
29052227Adjuvant pretreatment with alum protects neonatal mice in sepsis through myeloid cell activation.Clin Exp Immunol2018
29271527Chorioamnionitis, IL-17A, and fetal origins of neurologic disease.Am J Reprod Immunol2018
29243317IL-17 in neonatal health and disease.Am J Reprod Immunol2018
29019470Progress in the management of neonatal sepsis: the importance of a consensus definition.Pediatr Res2018
27684425Oral colostrum priming shortens hospitalization without changing the immunomicrobial milieu.J Perinatol2017
28283553Genome-wide association study of sepsis in extremely premature infants.Arch Dis Child Fetal Neonatal Ed2017
28224121Immunological Defects in Neonatal Sepsis and Potential Therapeutic Approaches.Front Pediatr2017
29312907Editorial: The Neonatal Immune System: A Unique Host-Microbial Interface.Front Pediatr2017
28886074Unique transcriptomic response to sepsis is observed among patients of different age groups.PLoS One2017
28873345Neutrophil chemotaxis and transcriptomics in term and preterm neonates.Transl Res2017
28690615Impact of Early-Life Exposures to Infections, Antibiotics, and Vaccines on Perinatal and Long-term Health and Disease.Front Immunol2017
28628637Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles.PLoS One2017
27923248Timing of Multiorgan Dysfunction among Hospitalized Infants with Fatal Fulminant Sepsis.Am J Perinatol2017
27030919Lethal neonatal meningoencephalitis caused by multi-drug resistant, highly virulent Escherichia coli.Infect Dis (Lond)2016
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Collaborators

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Co-authored papers 11
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University of Florida, College of Medicine-Jacksonville
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University of Florida Health
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Boston Children's Hospital
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Mott Children's Hospital
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Pediatrix Center for Research Education
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Bicetre Medical Centre, Paris Saclay University
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University of Florida
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Sainte Justine and Montreal Heart Institute, University of Montreal
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Institute for Global Health, British Columbia Children's & Women's Hospital
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Sidney Kimmel Medical College at Thomas Jefferson University
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University of Florida College of Medicine
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