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Author Details

Ron Bose
Washington University School of Medicine
1991
74
38
PMIDPaper TitleJournal TitlePublished Year
36702070Final findings from the CONTROL trial: Strategies to reduce the incidence and severity of neratinib-associated diarrhea in patients with HER2-positive early-stage breast cancer.Breast2023
37597578Neratinib + fulvestrant + trastuzumab for HR-positive, HER2-negative, HER2-mutant metastatic breast cancer: outcomes and biomarker analysis from the SUMMIT trial.Ann Oncol2023
37272756Breast Cancer Mutations HER2V777L and PIK3CAH1047R Activate the p21-CDK4/6-Cyclin D1 Axis to Drive Tumorigenesis and Drug Resistance.Cancer Res2023
37265453Genetic Alterations Detected by Circulating Tumor DNA in HER2-Low Metastatic Breast Cancer.Clin Cancer Res2023
35173164Cardiac outcomes of subjects on adjuvant trastuzumab emtansine vs paclitaxel in combination with trastuzumab for stage I HER2-positive breast cancer (ATEMPT) study (TBCRC033): a randomized controlled trial.NPJ Breast Cancer2022
36332363Circulating tumour DNA characterisation of invasive lobular carcinoma in patients with metastatic breast cancer.EBioMedicine2022
35046057The Phase II MutHER Study of Neratinib Alone and in Combination with Fulvestrant in HER2-Mutated, Non-amplified Metastatic Breast Cancer.Clin Cancer Res2022
33219484Mutation profile differences in younger and older patients with advanced breast cancer using circulating tumor DNA (ctDNA).Breast Cancer Res Treat2021
33909203Neratinib⿿+⿿capecitabine sustains health-related quality of life in patients with HER2-positive metastatic breast cancer and⿿⿥⿿2 prior HER2-directed regimens.Breast Cancer Res Treat2021
33591468The efficacy and safety of enzalutamide with trastuzumab in patients with HER2+â¿¿and androgen receptor-positive metastatic or locally advanced breast cancer.Breast Cancer Res Treat2021
33930605HER2 and APC Mutations Promote Altered Crypt-Villus Morphology and Marked Hyperplasia in the Intestinal Epithelium.Cell Mol Gastroenterol Hepatol2021
34551235Breast Cancer, <i>HER2</i> Mutations, and Overcoming Drug Resistance.N Engl J Med2021
34077270Adjuvant Trastuzumab Emtansine Versus Paclitaxel in Combination With Trastuzumab for Stage I HER2-Positive Breast Cancer (ATEMPT): A Randomized Clinical Trial.J Clin Oncol2021
34120223Chemotherapy-related amenorrhea (CRA) after adjuvant ado-trastuzumab emtansine (T-DM1) compared to paclitaxel in combination with trastuzumab (TH) (TBCRC033: ATEMPT Trial).Breast Cancer Res Treat2021
34173924Immunogenomic profiling and pathological response results from a clinical trial of docetaxel and carboplatin in triple-negative breast cancer.Breast Cancer Res Treat2021
34339623Pertuzumab and trastuzumab for HER2-positive, metastatic biliary tract cancer (MyPathway): a multicentre, open-label, phase 2a, multiple basket study.Lancet Oncol2021
34028126Efficacy of Neratinib Plus Capecitabine in the Subgroup of Patients with Central Nervous System Involvement from the NALA Trial.Oncologist2021
33179922Phosphorylation-Dependent Conformations of the Disordered Carboxyl-Terminus Domain in the Epidermal Growth Factor Receptor.J Phys Chem Lett2020
32067683Targeted therapy for advanced salivary gland carcinoma based on molecular profiling: results from MyPathway, a phase IIa multiple basket study.Ann Oncol2020
30676778Imaging of HER2 with [<sup>89</sup>Zr]pertuzumab in Response to T-DM1 Therapy.Cancer Biother Radiopharm2019
32923853Identifying <i>ERBB2</i> Activating Mutations in HER2-Negative Breast Cancer: Clinical Impact of Institute-Wide Genomic Testing and Enrollment in Matched Therapy Trials.JCO Precis Oncol2019
30857956Pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer (MyPathway): an updated report from a multicentre, open-label, phase 2a, multiple basket study.Lancet Oncol2019
30787127Retrospective Analysis of Treatment Patterns and Effectiveness of Palbociclib and Subsequent Regimens in Metastatic Breast Cancer.J Natl Compr Canc Netw2019
29320312Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study.J Clin Oncol2018
30181556The prognostic effects of somatic mutations in ER-positive breast cancer.Nat Commun2018
29856693Reply to J.J. Tao et al.J Clin Oncol2018
30429476Author Correction: The prognostic effects of somatic mutations in ER-positive breast cancer.Nat Commun2018
29442264Evaluation of [<sup>89</sup>Zr]trastuzumab-PET/CT in differentiating HER2-positive from HER2-negative breast cancer.Breast Cancer Res Treat2018
27872189Biophysical Evidence for Intrinsic Disorder in the C-terminal Tails of the Epidermal Growth Factor Receptor (EGFR) and HER3 Receptor Tyrosine Kinases.J Biol Chem2017
35172500Response of a Metastatic Breast Carcinoma With a Previously Uncharacterized ERBB2 G776V Mutation to Human Epidermal Growth Factor Receptor 2-Targeted Therapy.JCO Precis Oncol2017
28088451Efficient sortase-mediated N-terminal labeling of TEV protease cleaved recombinant proteins.Anal Biochem2017
28138153CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer.Nat Genet2017
28743916Analysis of somatic mutations across the kinome reveals loss-of-function mutations in multiple cancer types.Sci Rep2017
28679771Neratinib Efficacy and Circulating Tumor DNA Detection of <i>HER2</i> Mutations in <i>HER2</i> Nonamplified Metastatic Breast Cancer.Clin Cancer Res2017
27078022Neratinib Plus Paclitaxel vs Trastuzumab Plus Paclitaxel in Previously Untreated Metastatic ERBB2-Positive Breast Cancer: The NEfERT-T Randomized Clinical Trial.JAMA Oncol2016
27618449Unsupervised detection of cancer driver mutations with parsimony-guided learning.Nat Genet2016
27146421[[89]Zr]Trastuzumab: Evaluation of Radiation Dosimetry, Safety, and Optimal Imaging Parameters in Women with HER2-Positive Breast Cancer.Mol Imaging Biol2016
27284958Nonamplification ERBB2 genomic alterations in 5605 cases of recurrent and metastatic breast cancer: An emerging opportunity for anti-HER2 targeted therapies.Cancer2016
26987533Prognostic and Predictive Biomarkers of Endocrine Responsiveness for Estrogen Receptor Positive Breast Cancer.Adv Exp Med Biol2016
26926684Genomic Characterization of Primary Invasive Lobular Breast Cancer.J Clin Oncol2016
26124280Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor.Mol Cell Biol2015
26358790HER2-Mutated Breast Cancer Responds to Treatment With Single-Agent Neratinib, a Second-Generation HER2/EGFR Tyrosine Kinase Inhibitor.J Natl Compr Canc Netw2015
26508629HER2 missense mutations have distinct effects on oncogenic signaling and migration.Proc Natl Acad Sci U S A2015
26243863HER2 activating mutations are targets for colorectal cancer treatment.Cancer Discov2015
26209800Statistically identifying tumor suppressors and oncogenes from pan-cancer genome-sequencing data.Bioinformatics2015
24723360Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer.Electrophoresis2014
23105007Quantitative proteomics with siRNA screening identifies novel mechanisms of trastuzumab resistance in HER2 amplified breast cancers.Mol Cell Proteomics2013
24298067Incorporating genomics into breast cancer clinical trials and care.Clin Cancer Res2013
24122041DGIdb: mining the druggable genome.Nat Methods2013
24055055Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts.Cell Rep2013
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University of California san francisco
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