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Author Details

Paul D Robbins
University of Minnesota
1986
515
109
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38051584Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia.JCI Insight2024
35015337Targeting cellular senescence with senotherapeutics: senolytics and senomorphics.FEBS J2023
37292828The regulation of Insulin/IGF-1 signaling by miR-142-3p associated with human longevity.bioRxiv2023
37291596Aging and chronic inflammation: highlights from a multidisciplinary workshop.Immun Ageing2023
37189433Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities.Biomolecules2023
37154858In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers.Aging (Albany NY)2023
36976763microRNA-449a reduces growth hormone-stimulated senescent cell burden through PI3K-mTOR signaling.Proc Natl Acad Sci U S A2023
36722290A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.EMBO J2023
36809340Local senolysis in aged mice only partially replicates the benefits of systemic senolysis.J Clin Invest2023
36508307Osteoarthritis gene therapy in 2022.Curr Opin Rheumatol2023
36931996A report on the International Society for Cell & Gene Therapy 2022 Scientific Signature Series, "Therapeutic advances with native and engineered human extracellular vesicles".Cytotherapy2023
36734200Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy.Aging Cell2023
36865244<i>In vitro</i> and <i>in vivo</i> effects of zoledronate on senescence and senescence-associated secretory phenotype markers.bioRxiv2023
36198912COVID-19 and cellular senescence.Nat Rev Immunol2023
34825304miR-146a-5p modulates cellular senescence and apoptosis in visceral adipose tissue of long-lived Ames dwarf mice and in cultured pre-adipocytes.Geroscience2022
35821850Immune Senescence, Immunosenescence and Aging.Front Aging2022
35363946Targeted clearance of p21- but not p16-positive senescent cells prevents radiation-induced osteoporosis and increased marrow adiposity.Aging Cell2022
35417855Heterochronic parabiosis: a valuable tool to investigate cellular senescence and other hallmarks of aging.Aging (Albany NY)2022
36239841Cellular Senescence in Obesity and Associated Complications: a New Therapeutic Target.Curr Diab Rep2022
36170431Targeting Cellular Senescence with Senotherapeutics: Development of New Approaches for Skin Care.Plast Reconstr Surg2022
36084954Senolytic elimination of senescent macrophages restores muscle stem cell function in severely dystrophic muscle.Aging (Albany NY)2022
36218080Reduction of senescent fibro-adipogenic progenitors in progeria-aged muscle by senolytics rescues the function of muscle stem cells.J Cachexia Sarcopenia Muscle2022
35974106A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues.Nat Commun2022
35912854Cellular senescence: a key therapeutic target in aging and diseases.J Clin Invest2022
35015744Chronic HIV Infection and Aging: Application of a Geroscience-Guided Approach.J Acquir Immune Defic Syndr2022
32997601Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span.Annu Rev Pharmacol Toxicol2021
37117627Rare genetic coding variants associated with human longevity and protection against age-related diseases.Nat Aging2021
33684669Intersection of immunometabolism and immunosenescence during aging.Curr Opin Pharmacol2021
33902007Targeting ATM to mitigate intervertebral disc degeneration.Aging (Albany NY)2021
33512317DNA damage-how and why we age?Elife2021
33728821Mesenchymal stem cell-derived extracellular vesicles reduce senescence and extend health span in mouse models of aging.Aging Cell2021
34437305Orthopaedic Gene Therapy: Twenty-Five Years On.JBJS Rev2021
34734460Novel small molecule inhibition of IKK/NF-κB activation reduces markers of senescence and improves healthspan in mouse models of aging.Aging Cell2021
34375437Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era.J Am Geriatr Soc2021
34656616Recent advances in the discovery of senolytics.Mech Ageing Dev2021
34531331SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3.Aging (Albany NY)2021
34103349Senolytics reduce coronavirus-related mortality in old mice.Science2021
33981041An aged immune system drives senescence and ageing of solid organs.Nature2021
34363464Role of Cellular Senescence in Type II Diabetes.Endocrinology2021
34197020Genetic signature of human longevity in PKC and NF-κB signaling.Aging Cell2021
33406219Senolytic Combination of Dasatinib and Quercetin Alleviates Intestinal Senescence and Inflammation and Modulates the Gut Microbiome in Aged Mice.J Gerontol A Biol Sci Med Sci2021
32285290Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues.Geroscience2020
37113577Development of an IGF1R longevity variant mouse line using CRISPR/Cas9 genome editing.Trends Biomed Res2020
33708359Hitting the Bullseye: Are extracellular vesicles on target?J Extracell Vesicles2020
31981461Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice.Aging Cell2020
31818691Urinary Extracellular Vesicles Carrying Klotho Improve the Recovery of Renal Function in an Acute Tubular Injury Model.Mol Ther2020
33353886The Ercc<i>1</i><sup>-/ο</sup> mouse model of accelerated senescence and aging for identification and testing of novel senotherapeutic interventions.Aging (Albany NY)2020
32719537Genetics of extreme human longevity to guide drug discovery for healthy ageing.Nat Metab2020
32710480Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson-Gilford Progeria Syndrome.Aging Cell2020
32527988Influences of circulatory factors on intervertebral disc aging phenotype.Aging (Albany NY)2020
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Collaborators

Laura J Niedernhofer
University of Minnesota
Co-authored papers 93
Simon C Watkins
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Co-authored papers 37
Sundeep Khosla
Co-authored papers 11
Aiping Lu
Co-authored papers 10
Nir Barzilai
Co-authored papers 10
Yinsheng Wang
Co-authored papers 7
Elizabeth J Atkinson
Mayo Clinic
Co-authored papers 7
Timothy R Billiar
University of Pittsburgh
Co-authored papers 5
Steffen Gay
Co-authored papers 5
Maliha Zahid
Co-authored papers 5
Gil Atzmon
Co-authored papers 4
Hideho Okada
Co-authored papers 4
Bobby G Ng
Co-authored papers 3
Gary Siuzdak
Scripps Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute
Co-authored papers 3
Zhengdong D Zhang
Co-authored papers 3
Vera Gorbunova
University of Rochester
Co-authored papers 3
Meenhard Herlyn
Ellen and Ronald Caplan Cancer Center, The Wistar Institute
Co-authored papers 3
Arthur M Feldman
Co-authored papers 3
Thomas Pap
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Michael R Botchan
University of California berkeley
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Bennett Van Houten
UPMC-Hillman Cancer Center, University of Pittsburgh
Co-authored papers 2
Aries Aisporna
Scripps Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute
Co-authored papers 2
Theodore M Kamenecka
Co-authored papers 2
Luke L Lairson
The Scripps Research Institute
Co-authored papers 2
Michael W W Adams
University of Georgia
Co-authored papers 2
Hilary P Benton
Scripps Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute
Co-authored papers 2
Matthew W Fields
Center for Biofilm Engineering (CBE), Montana State University
Co-authored papers 2
Ronna L Campbell
Mayo Clinic College of Medicine and Science
Co-authored papers 2
Nathan A Yates
University of Pittsburgh School of Medicine
Co-authored papers 2
James R Goss
Gilbert Family Foundation
Co-authored papers 2
Release 1.2