Author details

Full Name

Casey E Romanoski

Affiliation

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37437844	SREBP2 regulates the endothelial response to cytokines via direct transcriptional activation of KLF6.		2023
38031841	Unraveling the Role of Sex in Endothelial Cell Dysfunction: Evidence From Lineage Tracing Mice and Cultured Cells.		2023
37695914	TNFÎ± increases the degradation of pyruvate dehydrogenase kinase 4 by the Lon protease to support proinflammatory genes.		2023
36971339	Transcriptional drifts associated with environmental changes in endothelial cells.	Elife	2023
37066416	Single cell 'omic profiles of human aortic endothelial cells and human atherosclerotic lesions reveals heterogeneity of endothelial subtype and response to activating perturbations.		2023
35049498	Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs.	Elife	2022
34697471	Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2.	Nature Metabolism	2021
34178388	Meta-Analysis of Smooth Muscle Lineage Transcriptomes in Atherosclerosis and Their Relationships to In Vitro Models.		2021
33532862	Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.	Eur Heart J	2021
33626337	Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease.	Am J Hum Genet	2021
34192535	Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.	Cell Reports	2021
34024118	Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci.	Circ Res	2021
33326355	CC16 Binding to Î±<sub>4</sub>Î²<sub>1</sub> Integrin Protects against <i>Mycoplasma pneumoniae</i> Infection.	Am J Respir Crit Care Med	2021
33343881	Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes.	Pulm Circ	2020
31959980	Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung.	Nat Immunol	2020
32442411	Systems Genetics in Human Endothelial Cells Identifies Non-coding Variants Modifying Enhancers, Expression, and Complex Disease Traits.	American Journal of Human Genetics	2020
32878927	Transcriptional Profiling Suggests T Cells Cluster around Neurons Injected with Toxoplasma gondii Proteins.	mSphere	2020
32649217	Rhinovirus Infections in Individuals with Asthma Increase ACE2 Expression and Cytokine Pathways Implicated in COVID-19.	Am J Respir Crit Care Med	2020
30598475	An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner.	J Lipid Res	2019
29779944	Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function.	Cell	2018
30429326	Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics.	Proc Natl Acad Sci U S A	2018
29895827	Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells.	Nat Commun	2018
29893919	MMARGE: Motif Mutation Analysis for Regulatory Genomic Elements.	Nucleic Acids Res	2018
28585919	Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells.	Elife	2017
27814941	Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6C<sup>low</sup> Monocytes while Preserving Macrophage Gene Function.	Immunity	2016
26298065	Exploiting genomics and natural genetic variation to decode macrophage enhancers.	Trends Immunol	2015
25846707	Siglec receptors impact mammalian lifespan by modulating oxidative stress.	Elife	2015
25693562	Epigenomics: Roadmap for regulation.	Nature	2015
25651182	MAFG is a transcriptional repressor of bile acid synthesis and metabolism.	Cell Metab	2015
25650801	The selection and function of cell type-specific enhancers.	Nat Rev Mol Cell Biol	2015
25480297	Environment drives selection and function of enhancers controlling tissue-specific macrophage identities.	Cell	2014
25352550	Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization.	Nucleic Acids Res	2014
23667179	Identification of CAD candidate genes in GWAS loci and their expression in vascular cells.	J Lipid Res	2013
24121437	Effect of natural genetic variation on enhancer selection and function.	Nature	2013
24349443	Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease.	PLoS One	2013
24189069	25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages.	J Biol Chem	2013
23932714	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	Mol Cell	2013
22402363	Metalloproteinase processing of HBEGF is a proximal event in the response of human aortic endothelial cells to oxidized phospholipids.	Arteriosclerosis, Thrombosis, and Vascular Biology	2012
22935534	Role of phospholipid oxidation products in atherosclerosis.	Circulation Research	2012
21737788	Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1.	Circ Res	2011
21836061	Paraoxonase-2 modulates stress response of endothelial cells to oxidized phospholipids and a bacterial quorum-sensing molecule.	Arteriosclerosis, Thrombosis, and Vascular Biology	2011
20170901	Systems genetics analysis of gene-by-environment interactions in human cells.	Am J Hum Genet	2010
18751557	A re-examination of the phylogenetic relationship between the causal agents of carrot black rot, Alternaria radicina and A. carotiincultae.	Mycologia	2008
18035925	Network-centered view of coronary artery disease.	Expert Review of Cardiovascular Therapy	2007