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Author Details

Andrew K Groves
Baylor College of Medicine
1991
100
42
PMIDPaper TitleJournal TitlePublished Year
36153788Early Wnt Signaling Activation Promotes Inner Ear Differentiation via Cell Caudalization in Mouse Stem Cell-Derived Organoids.Stem Cells2023
37596911Loss of heterozygosity does not occur in BRCA1/2 mutant pediatric solid and central nervous system tumors.Pediatr Blood Cancer2023
37549271DNA methylation in the mouse cochlea promotes maturation of supporting cells and contributes to the failure of hair cell regeneration.Proc Natl Acad Sci U S A2023
37543988Foxi3[GFP] and Foxi3[CreER] mice allow identification and lineage labeling of pharyngeal arch ectoderm and endoderm, and tooth and hair placodes.Dev Dyn2023
37041148FOXI3 pathogenic variants cause one form of craniofacial microsomia.Nat Commun2023
37227818Transcriptional dynamics of delaminating neuroblasts in the mouse otic vesicle.Cell Rep2023
36587458Fbxo2<sup>CreERT2</sup>: A new model for targeting cells in the neonatal and mature inner ear.Hear Res2023
34872929Lunatic Fringe-GFP Marks Lamina-Specific Astrocytes That Regulate Sensory Processing.J Neurosci2022
35551236GFI1 regulates hair cell differentiation by acting as an off-DNA transcriptional co-activator of ATOH1, and a DNA-binding repressor.Sci Rep2022
35745584Bromodomain and Extra-Terminal Protein Inhibitors: Biologic Insights and Therapeutic Potential in Pediatric Brain Tumors.Pharmaceuticals (Basel)2022
36589742Epigenetic programming of pediatric high-grade glioma: Pushing beyond proof of concept to clinical benefit.Front Cell Dev Biol2022
36305736BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.Cancer Discov2022
35987349FOXI3 haploinsufficiency contributes to low T-cell receptor excision circles and T-cell lymphopenia.J Allergy Clin Immunol2022
35037155The epidemiology of primary and metastatic brain tumors in infancy through childhood.J Neurooncol2022
35239393Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly.Science2022
34253626Glial-Specific Deletion of Med12 Results in Rapid Hearing Loss via Degradation of the Stria Vascularis.J Neurosci2021
33854418Transcription Factor Reprogramming in the Inner Ear: Turning on Cell Fate Switches to Regenerate Sensory Hair Cells.Front Cell Neurosci2021
34331868Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration.Dev Cell2021
31600545Recurrent microdeletions at chromosome 2p11.2 are associated with thymic hypoplasia and features resembling DiGeorge syndrome.J Allergy Clin Immunol2020
33058336Uncovering the secreted signals and transcription factors regulating the development of mammalian middle ear ossicles.Dev Dyn2020
33364980Building the Border: Development of the Chordate Neural Plate Border Region and Its Derivatives.Front Physiol2020
33293609Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea.Sci Rep2020
32686305The use of interval-compressed chemotherapy with the addition of vincristine, irinotecan, and temozolomide for pediatric patients with newly diagnosed desmoplastic small round cell tumor.Pediatr Blood Cancer2020
32121147Hear, Hear for Notch: Control of Cell Fates in the Inner Ear by Notch Signaling.Biomolecules2020
32147304Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development.Dev Biol2020
32482884Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal.Proc Natl Acad Sci U S A2020
31033441Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1.Elife2019
31341285Resolving medulloblastoma cellular architecture by single-cell genomics.Nature2019
30467319Foxi3 transcription factor activity is mediated by a C-terminal transactivation domain and regulated by the Protein Phosphatase 2A (PP2A) complex.Sci Rep2018
29853544Using <i>Drosophila</i> to study mechanisms of hereditary hearing loss.Dis Model Mech2018
28699891Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance.Elife2017
28729444An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment.J Neurosci2017
26052920Where hearing starts: the development of the mammalian cochlea.J Anat2016
26550799The mouse Foxi3 transcription factor is necessary for the development of posterior placodes.Dev Biol2016
27966429Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates.Elife2016
27630544Editorial: Sensory Hair Cell Death and Regeneration.Front Cell Neurosci2016
27918591Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing.PLoS One2016
27331610The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals.Elife2016
27195754Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.PLoS Genet2016
26992132Foxi3 Deficiency Compromises Hair Follicle Stem Cell Specification and Activation.Stem Cells2016
27090805Lineage tracing of Sox2-expressing progenitor cells in the mouse inner ear reveals a broad contribution to non-sensory tissues and insights into the origin of the organ of Corti.Dev Biol2016
26952139The molecular basis of craniofacial placode development.Wiley Interdiscip Rev Dev Biol2016
24902666Segregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control.Cell Tissue Res2015
26450968Suppression of epithelial differentiation by Foxi3 is essential for molar crown patterning.Development2015
25855195Characterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factor.J Neurosci2015
25873862Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea.Front Cell Neurosci2015
25655429Congenital aural atresia associated with agenesis of internal carotid artery in a girl with a FOXI3 deletion.Am J Med Genet A2015
25662269The role of foxi family transcription factors in the development of the ear and jaw.Curr Top Dev Biol2015
25781991Tfap2a promotes specification and maturation of neurons in the inner ear through modulation of Bmp, Fgf and notch signaling.PLoS Genet2015
25339580The Role of Atonal Factors in Mechanosensory Cell Specification and Function.Mol Neurobiol2015
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Collaborators

University of Rochester Medical Center
Co-authored papers 7
UCL Institute of Prion Diseases
Co-authored papers 5
Co-authored papers 3
University of Glasgow, University Place
Co-authored papers 3
Molecular and Clinical Sciences Research Institute, University of London
Co-authored papers 3
Baylor College of Medicine
Co-authored papers 3
Clinical Imaging Group, Inc.
Co-authored papers 3
Co-authored papers 2
Broad Institute of MIT and Harvard
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Institute of Stem Cells and Regenerative Medicine (inStem)
Co-authored papers 2
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 2
Co-authored papers 2
Baylor College of Medicine, TX Jan and Dan Duncan Neurological Research Institute
Co-authored papers 2
Frimley Health NHS Foundation Trust
Co-authored papers 1
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
The Ludwig Institute for Cancer Research
Co-authored papers 1
Dana-Farber Cancer Institute
Co-authored papers 1
Co-authored papers 1
University of Southern California Keck School of Medicine
Co-authored papers 1
University of Alabama at Birmingham
Co-authored papers 1
Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu
Co-authored papers 1
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