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Author Details

Stanley Fields
University of Washington
1985
185
75
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37398426<i>Arabidopsis</i> and Maize Terminator Strength is Determined by GC Content, Polyadenylation Motifs and Cleavage Probability.bioRxiv2024
35315272Comprehensive Mutational Analysis of the Lasso Peptide Klebsidin.ACS Chem Biol2022
35760818Publisher Correction: Expanding the binding specificity for RNA recognition by a PUF domain.Nat Commun2022
35749361Mapping functional regions of essential bacterial proteins with dominant-negative protein fragments.Proc Natl Acad Sci U S A2022
34083762Synthetic promoter designs enabled by a comprehensive analysis of plant core promoters.Nat Plants2021
33589767Balance between promiscuity and specificity in phage λ host range.ISME J2021
34429425Expanding the binding specificity for RNA recognition by a PUF domain.Nat Commun2021
34663436Effects of sequence motifs in the yeast 3' untranslated region determined from massively parallel assays of random sequences.Genome Biol2021
34099698The regulatory landscape of Arabidopsis thaliana roots at single-cell resolution.Nat Commun2021
32238226Distinct patterns of mutational sensitivity for <i>λ</i> resistance and maltodextrin transport in <i>Escherichia coli</i> LamB.Microb Genom2020
31810988Binding and Regulation of Transcription by Yeast Ste12 Variants To Drive Mating and Invasion Phenotypes.Genetics2020
32210240Dimensionality reduction by UMAP to visualize physical and genetic interactions.Nat Commun2020
32409318Identification of Plant Enhancers and Their Constituent Elements by STARR-seq in Tobacco Leaves.Plant Cell2020
30962621High-throughput identification of dominant negative polypeptides in yeast.Nat Methods2019
30923229Dynamics of Gene Expression in Single Root Cells of Arabidopsis thaliana.Plant Cell2019
29272536Complex Relationships between Chromatin Accessibility, Sequence Divergence, and Gene Expression in Arabidopsis thaliana.Mol Biol Evol2018
30219179A Multiplex Homology-Directed DNA Repair Assay Reveals the Impact of More Than 1,000 BRCA1 Missense Substitution Variants on Protein Function.Am J Hum Genet2018
30068600Preferences in a trait decision determined by transcription factor variants.Proc Natl Acad Sci U S A2018
30204430Engineered Biosensors from Dimeric Ligand-Binding Domains.ACS Synth Biol2018
30064218A Biosensor Strategy for E. coli Based on Ligand-Dependent Stabilization.ACS Synth Biol2018
30007351Conditional accumulation of toxic tRNAs to cause amino acid misincorporation.Nucleic Acids Res2018
29259051Widespread temperature sensitivity and tRNA decay due to mutations in a yeast tRNA.RNA2018
28652265A Massively Parallel Fluorescence Assay to Characterize the Effects of Synonymous Mutations on <i>TP53</i> Expression.Mol Cancer Res2017
29097404Deep learning of the regulatory grammar of yeast 5' untranslated regions from 500,000 random sequences.Genome Res2017
26936925Comprehensive Analysis of the SUL1 Promoter of Saccharomyces cerevisiae.Genetics2016
27270695Massively Parallel Genetics.Genetics2016
27374328Adjacent Codons Act in Concert to Modulate Translation Efficiency in Yeast.Cell2016
26689263Engineering an allosteric transcription factor to respond to new ligands.Nat Methods2016
25559584Massively parallel single-amino-acid mutagenesis.Nat Methods2015
26543197The role of functional data in interpreting the effects of genetic variation.Mol Biol Cell2015
26350354Functional Analysis of BARD1 Missense Variants in Homology-Directed Repair of DNA Double Strand Breaks.Hum Mutat2015
26714111A general strategy to construct small molecule biosensors in eukaryotes.Elife2015
26240414Deep Mutational Scanning: A Highly Parallel Method to Measure the Effects of Mutation on Protein Function.Cold Spring Harb Protoc2015
26240406Deep Mutational Scanning: Calculating Enrichment Scores for Protein Variants from DNA Sequencing Output Files.Cold Spring Harb Protoc2015
26240405Deep Mutational Scanning: Library Construction, Functional Selection, and High-Throughput Sequencing.Cold Spring Harb Protoc2015
25671604Combining natural sequence variation with high throughput mutational data to reveal protein interaction sites.PLoS Genet2015
25823446Massively Parallel Functional Analysis of BRCA1 RING Domain Variants.Genetics2015
25742460A tetO Toolkit To Alter Expression of Genes in Saccharomyces cerevisiae.ACS Synth Biol2015
24939989Would Fred Sanger get funded today?Genetics2014
25584376The yeast two-hybrid assay: still finding connections after 25 years.Nat Methods2014
25306102Engineering allostery.Trends Genet2014
25075907Deep mutational scanning: a new style of protein science.Nat Methods2014
25085423Identification of the determinants of tRNA function and susceptibility to rapid tRNA decay by high-throughput in vivo analysis.Genes Dev2014
25167058Measuring the activity of protein variants on a large scale using deep mutational scanning.Nat Protoc2014
24919400A homolog of lariat-debranching enzyme modulates turnover of branched RNA.RNA2014
23509263Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis.Proc Natl Acad Sci U S A2013
24064791Deep mutational scanning of an RRM domain of the Saccharomyces cerevisiae poly(A)-binding protein.RNA2013
24244371Protein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptide.PLoS One2013
23897579High-throughput analysis of in vivo protein stability.Mol Cell Proteomics2013
23625929Engineering A-kinase anchoring protein (AKAP)-selective regulatory subunits of protein kinase A (PKA) through structure-based phage selection.J Biol Chem2013
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Collaborators

Christine Queitsch
University of Washington
Co-authored papers 10
Lea M Starita
University of Washington and Brotman Baty Institute for Precision Medicine
Co-authored papers 10
Douglas M Fowler
University of Washington, USA Brotman Baty Institute for Precision Medicine
Co-authored papers 9
Peter Uetz
Center for the Study of Biological Complexity, Virginia Commonwealth University
Co-authored papers 8
Jay Shendure
University of Washington
Co-authored papers 7
David Baker
University of Washington
Co-authored papers 6
Gerard Cagney
Conway Institute of Biomedical and Biomolecular Sciences, University College Dublin
Co-authored papers 6
Douglas J LaCount
Purdue University
Co-authored papers 6
William Stafford Noble
Co-authored papers 5
Trisha N Davis
University of Washington
Co-authored papers 5
Mark Johnston
University of Colorado School of Medicine
Co-authored papers 4
Philip Hieter
University of British Columbia
Co-authored papers 4
George M Church
Harvard Medical School
Co-authored papers 3
Gary D Bader
University of Toronto
Co-authored papers 3
Sara J Cooper
Co-authored papers 3
Eric G D Muller
University of Washington
Co-authored papers 3
Amy Hin Yan Tong
University of Toronto
Co-authored papers 3
Charles Boone
University of Toronto
Co-authored papers 3
Christopher W V Hogue
National University of Singapore
Co-authored papers 3
Gianni Cesareni
University of Rome 'Tor Vergata'
Co-authored papers 3
David G Drubin
University of California berkeley
Co-authored papers 3
Michael Riffle
University of Washington
Co-authored papers 2
Kimberly M Dean
Center for RNA Biology, University of Rochester School of Medicine and Dentistry
Co-authored papers 2
Russell Bell
Huntsman Cancer Institute at the University of Utah
Co-authored papers 2
Michael J MacCoss
University of Washington
Co-authored papers 2
Sudhir Sahasrabudhe
University of Medicine and Dentistry of New Jersey, New Jersey Medical School
Co-authored papers 2
Igor Stagljar
University of Toronto, Canada Mediterranean Institute for Life Sciences
Co-authored papers 2
Brian E Snydsman
Co-authored papers 2
Christopher E Aston
Co-authored papers 2
Mark Gerstein
Yale University
Co-authored papers 2
Release 1.2