Author details

Full Name

Michael R Stratton

Affiliation

Wellcome Sanger Institute

ORCID

Career Start Year

1987

Papers

347

H Index

140

Expertise

CM4AI Collaborator

Emma Lundberg (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36702998	APOBEC mutagenesis is a common process in normal human small intestine.	Nat Genet	2023
37502962	Assigning mutational signatures to individual samples and individual somatic mutations with SigProfilerAssignment.	bioRxiv	2023
38096571	Assigning mutational signatures to individual samples and individual somatic mutations with SigProfilerAssignment.	Bioinformatics	2023
37079675	The evolution of two transmissible cancers in Tasmanian devils.	Science	2023
36697836	Author Correction: The repertoire of mutational signatures in human cancer.	Nature	2023
36539619	Author Correction: Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro.	Nat Genet	2023
36388765	Uncovering novel mutational signatures by <i>de novo</i> extraction with SigProfilerExtractor.	Cell Genom	2022
35803914	Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells.	Nat Commun	2022
35650442	Clonal dynamics of haematopoiesis across the human lifespan.	Nature	2022
35581206	Mutational landscape of normal epithelial cells in Lynch Syndrome patients.	Nat Commun	2022
35469014	Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR Ã¿ LGR5 bispecific antibody with efficacy in epithelial tumors.	Nat Cancer	2022
35418684	Somatic mutation rates scale with lifespan across mammals.	Nature	2022
35859169	Mechanisms of APOBEC3 mutagenesis in human cancer cells.	Nature	2022
33318691	Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing.	Nat Protoc	2021
33911282	Somatic mutation landscapes at single-molecule resolution.	Nature	2021
34857954	Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro.	Nat Genet	2021
34646017	Convergent somatic mutations in metabolism genes in chronic liver disease.	Nature	2021
34433963	Extensive phylogenies of human development inferred from somatic mutations.	Nature	2021
34433962	The mutational landscape of human somatic and germline cells.	Nature	2021
34663923	Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence.	Nat Genet	2021
34594041	Increased somatic mutation burdens in normal human cells due to defective DNA polymerases.	Nat Genet	2021
32350471	The mutational landscape of normal human endometrial epithelium.	Nature	2020
31996850	Tobacco smoking and somatic mutations in human bronchial epithelium.	Nature	2020
31723001	Association of Genomic Domains in <i>BRCA1</i> and <i>BRCA2</i> with Prostate Cancer Risk and Aggressiveness.	Cancer Res	2020
31949161	A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.	Nat Commun	2020
33232318	Evolution and lineage dynamics of a transmissible cancer in Tasmanian devils.	PLoS Biol	2020
33004514	Extensive heterogeneity in somatic mutation and selection in the human bladder.	Science	2020
32673568	Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.	Cell Stem Cell	2020
33022221	Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk.	Am J Hum Genet	2020
32697969	Somatic Evolution in Non-neoplastic IBD-Affected Colon.	Cell	2020
29602208	Recurrent histone mutations in T-cell acute lymphoblastic leukaemia.	Br J Haematol	2019
31645730	The landscape of somatic mutation in normal colorectal epithelial cells.	Nature	2019
31806814	Embryonal precursors of Wilms tumor.	Science	2019
31548585	Publisher Correction: Shared heritability and functional enrichment across six solid cancers.	Nat Commun	2019
31371581	Somatic evolution and global expansion of an ancient transmissible cancer lineage.	Science	2019
30988298	Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation.	Nat Commun	2019
30849372	Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis.	Cell	2019
30683880	Shared heritability and functional enrichment across six solid cancers.	Nat Commun	2019
29323295	Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells.	Nature	2018
29915264	Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants.	Nat Commun	2018
30185910	Population dynamics of normal human blood inferred from somatic mutations.	Nature	2018
29858576	Recurrent rearrangements of FOS and FOSB define osteoblastoma.	Nat Commun	2018
29906452	Universal Patterns of Selection in Cancer and Somatic Tissues.	Cell	2018
30202019	The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.	Nat Commun	2018
30337457	Somatic mutant clones colonize the human esophagus with age.	Science	2018
30559362	Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors.	Nat Commun	2018
29643510	Intra-tumour diversification in colorectal cancer at the single-cell level.	Nature	2018
28904067	Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency.	Cancer Res	2017
28112740	A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers.	Nat Genet	2017
28288110	HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.	Nat Med	2017

1 - 50 of 347

Aurelie Vogt

Frederick National Laboratory for Cancer Research (FNLCR), Inc.

Career Start Year 2012

Number of shared co-authors 23

Sigve Nakken

University of Oslo

Career Start Year 2007

Number of shared co-authors 40

Paz Polak

McGill University

Career Start Year 2006

Number of shared co-authors 27

Nicola Waddell

QIMR Berghofer Medical Research Institute

Career Start Year 2006

Number of shared co-authors 89

Katia Nones

QIMR Berghofer Medical Research Institute

Career Start Year 2006

Number of shared co-authors 37

Ann-Marie Patch

QIMR Berghofer Medical Research Institute

Career Start Year 2005

Number of shared co-authors 78

Robert C Onofrio

The Broad Institute of Harvard and MIT

Career Start Year 2005

Number of shared co-authors 58

Jamie K Teer

H. Lee Moffitt Cancer Center and Research Institute

Career Start Year 2005

Number of shared co-authors 40

Laurie Burdett

National Cancer Institute, Frederick National Laboratory for Cancer Research

Career Start Year 2005

Number of shared co-authors 36

Kasmintan A Schrader

University of British Columbia

Career Start Year 2005

Number of shared co-authors 42

Rebecca Nagy

Guardant Health Inc.

Career Start Year 2004

Number of shared co-authors 12

Liying Zhang

The Fifth Affiliated Hospital, Sun Yat-sen University

Career Start Year 2004

Number of shared co-authors 31

Jianmin Wang

Roswell Park Comprehensive Cancer Center

Career Start Year 2003

Number of shared co-authors 0

Michael D McLellan

McDonnell Genome Institute, Washington University in St. Louis

Career Start Year 2003

Number of shared co-authors 21

Olivier Harismendy

University of California

Career Start Year 2003

Number of shared co-authors 7

Colin C Pritchard

University of Washington, USA Brotman Baty Institute for Precision Medicine

Career Start Year 1999

Number of shared co-authors 27

Dirce Maria Carraro

AC Camargo Cancer Center

Career Start Year 1998

Number of shared co-authors 12

Carrie Sougnez

The Broad Institute of Harvard and MIT

Career Start Year 1998

Number of shared co-authors 63

Li Ding

McDonnell Genome Institute, Washington University School of Medicine

Career Start Year 1997

Number of shared co-authors 49

Tom Walsh

University of Washington

Career Start Year 1996

Number of shared co-authors 21

Marbin Pineda

Center for Cancer Research, National Cancer Institute

Career Start Year 1995

Number of shared co-authors 23

Robert S Fulton

McDonnell Genome Institute, Washington University School of Medicine

Career Start Year 1994

Number of shared co-authors 58

Ming K Lee

University of Washington

Career Start Year 1988

Number of shared co-authors 9

Elaine R Mardis

The Ohio State University

Career Start Year 1988

Number of shared co-authors 94

Eivind Hovig

Center for Bioinformatics, University of Oslo

Career Start Year 1987

Number of shared co-authors 46

Maxwell P Lee

National Cancer Institute, National Institutes of Health

Career Start Year 1986

Number of shared co-authors 25

Alvaro N A Monteiro

H. Lee Moffitt Cancer Center & Research Institute

Career Start Year 1985

Number of shared co-authors 95

Edison T Liu

USA The Jackson Laboratory Cancer Center

Career Start Year 1982

Number of shared co-authors 21

Sharon E Plon

Baylor College of Medicine

Career Start Year 1982

Number of shared co-authors 35

Paul S Meltzer

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1970

Number of shared co-authors 78

row(s) 1 - 30 of 30

Phillip A Futreal

The University of Texas MD Anderson Cancer Center

Co-authored papers 106

Peter J Campbell

Wellcome Sanger Institute

Co-authored papers 89

Douglas F Easton

University of Cambridge

Co-authored papers 76

Patrick S Tarpey

Wellcome Trust Sanger Institute

Co-authored papers 56

Adam Butler

Wellcome Sanger Institute

Co-authored papers 53

Jon Teague

Wellcome Sanger Institute

Co-authored papers 53

Ludmil B Alexandrov

Moores Cancer Center, university of california san diego

Co-authored papers 43

Keiran Raine

Wellcome Sanger Institute

Co-authored papers 43

Sarah Edkins

Co-authored papers 42

Andrew Menzies

Wellcome Sanger Institute

Co-authored papers 42

Serena Nik-Zainal

Early Cancer Institute, University of Cambridge

Co-authored papers 40

Inigo Martincorena

Wellcome Sanger Institute

Co-authored papers 38

David Jones

Wellcome Sanger Institute

Co-authored papers 34

David C Wedge

Manchester Cancer Research Centre, University of Manchester

Co-authored papers 32

Sarah O'Meara

Clinical Research Facility, Mercy University Hospital

Co-authored papers 29

Chris Greenman

University of East Anglia

Co-authored papers 29

Peter Van Loo

The Francis Crick Institute

Co-authored papers 27

Barbara L Weber

Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania

Co-authored papers 26

Sunil R Lakhani

University of Queensland

Co-authored papers 25

Laura Mudie

Wellcome Trust Sanger Institute

Co-authored papers 24

Adrienne M Flanagan

University College London, UCL Cancer Institute

Co-authored papers 22

Lucy A Stebbings

Wellcome Trust Sanger Institute

Co-authored papers 22

Jonathan Hinton

Inivata Ltd

Co-authored papers 21

Colin S Cooper

Norwich Medical School, University of East Anglia

Co-authored papers 21

Charles E Schwartz

Co-authored papers 21

Frances Lucy Raymond

University of Cambridge, UK Cambridge University Hospitals NHS Foundation Trust

Co-authored papers 20

Anne-Lise B??rresen-Dale

Institute for Cancer Research, Oslo University Hospital

Co-authored papers 20

Rebecca Shepherd

Murdoch Children's Research Institute, Royal Children's Hospital

Co-authored papers 19

David E Goldgar

University of Utah

Co-authored papers 18

Katherine L Nathanson

Perelman School of Medicine, University of Pennsylvania, USA Abramson Cancer Center

Co-authored papers 18

1 - 30

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