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Author Details

Dirk Geerts
Amsterdam University Medical Center
1989
122
41
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36848144New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape.Biol Open2023
35081689Syntaxin 5 determines Weibel-Palade body size and von Willebrand factor secretion by controlling Golgi architecture.Haematologica2022
35675857HOXA1, a breast cancer oncogene.Biochim Biophys Acta Rev Cancer2022
35720311CAR T Cells Targeting Membrane-Bound Hsp70 on Tumor Cells Mimic Hsp70-Primed NK Cells.Front Immunol2022
36474162TWIST1 activates cancer stem cell marker genes to promote epithelial-mesenchymal transition and tumorigenesis in esophageal squamous cell carcinoma.BMC Cancer2022
36223680Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma.Eur J Med Chem2022
35100927Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer.J Drug Target2022
32336681Sec22b determines Weibel-Palade body length by controlling anterograde ER-Golgi transport.Haematologica2021
33488393Toward Biological Pacing by Cellular Delivery of Hcn2/SkM1.Front Physiol2021
34945011Differential Expression of Polyamine Pathways in Human Pancreatic Tumor Progression and Effects of Polyamine Blockade on Tumor Microenvironment.Cancers (Basel)2021
34490074HOXA1 Is an Antagonist of ERα in Breast Cancer.Front Oncol2021
33983539The endosomal RIN2/Rab5C machinery prevents VEGFR2 degradation to control gene expression and tip cell identity during angiogenesis.Angiogenesis2021
33074128RasGRP1 induces autophagy and transformation-associated changes in primary human keratinocytes.Transl Oncol2021
32318347Osteoprotegerin: Relationship to Breast Cancer Risk and Prognosis.Front Oncol2020
33391277Genetic Engineering of Natural Killer Cells for Enhanced Antitumor Function.Front Immunol2020
33415081Editorial: The Tumor Necrosis Factor Superfamily: An Increasing Role in Breast Cancer.Front Oncol2020
32478400The depot GnRH agonist protocol improves the live birth rate per fresh embryo transfer cycle, but not the cumulative live birth rate in normal responders: a randomized controlled trial and molecular mechanism study.Hum Reprod2020
30639262Anti-tumor effect of sulfasalazine in neuroblastoma.Biochem Pharmacol2019
31412613Establishment of Primary Transgenic Human Airway Epithelial Cell Cultures to Study Respiratory Virus-Host Interactions.Viruses2019
31417573Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function.Front Immunol2019
31416930MEIS transcription factors in development and disease.Development2019
30718504Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology.Cell Death Dis2019
30621310Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing.Molecules2019
29289661Notch signaling is impaired during inflammation in a Lunatic Fringe-dependent manner.Brain Behav Immun2018
29935642Cumulative live birth rates in more than 3,000 patients with poor ovarian response: a 15-year survey of final in vitro fertilization outcome.Fertil Steril2018
30115881Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy.Med Sci (Basel)2018
29956081p47phox-Dependent Reactive Oxygen Species Stimulate Nuclear Translocation of the FoxO1 Transcription Factor During Metabolic Inhibition in Cardiomyoblasts.Cell Biochem Biophys2018
30084753TGFBI Expressed by Bone Marrow Niche Cells and Hematopoietic Stem and Progenitor Cells Regulates Hematopoiesis.Stem Cells Dev2018
29977157Harmine, a dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor induces caspase-mediated apoptosis in neuroblastoma.Cancer Cell Int2018
30404920Polyamine synthesis as a target of <i>MYC</i> oncogenes.J Biol Chem2018
29501710Suppression of dsRNA response genes and innate immunity following Oct4, Stella, and Nanos2 overexpression in mouse embryonic fibroblasts.Cytokine2018
29358211The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB.J Cell Biol2018
29382709Tumorigenic and Antiproliferative Properties of the TALE-Transcription Factors MEIS2D and MEIS2A in Neuroblastoma.Cancer Res2018
29561911Correction: Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor.PLoS One2018
29323264Orai3 calcium channel and resistance to chemotherapy in breast cancer cells: the p53 connection.Cell Death Differ2018
29295892Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.Biochem J2018
28687780Nuclear receptors connect progenitor transcription factors to cell cycle control.Sci Rep2017
28249049Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor.PLoS One2017
28143606Osteoprotegerin mediates tumor-promoting effects of Interleukin-1beta in breast cancer cells.Mol Cancer2017
26741508Tumor sialylation impedes T cell mediated anti-tumor responses while promoting tumor associated-regulatory T cells.Oncotarget2016
26597010Acid Sphingomyelinase-Derived Ceramide Regulates ICAM-1 Function during T Cell Transmigration across Brain Endothelial Cells.J Immunol2016
26314854Predicting the molecular role of MEIS1 in esophageal squamous cell carcinoma.Tumour Biol2016
27794480Pluripotency induction in HEK293T cells by concurrent expression of STELLA, OCT4 and NANOS2.Biochem Biophys Res Commun2016
27829215RSK2 activity mediates glioblastoma invasiveness and is a potential target for new therapeutics.Oncotarget2016
27417273The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions.Nat Commun2016
27325287A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity.Diabetes2016
27382069HOXA1 binds RBCK1/HOIL-1 and TRAF2 and modulates the TNF/NF-κB pathway in a transcription-independent manner.Nucleic Acids Res2016
27183905Functional cooperation between KCa3.1 and TRPC1 channels in human breast cancer: Role in cell proliferation and patient prognosis.Oncotarget2016
27429841ATP13A3 and caveolin-1 as potential biomarkers for difluoromethylornithine-based therapies in pancreatic cancers.Am J Cancer Res2016
25769924Phenotypic variation in Aicardi-Goutières syndrome explained by cell-specific IFN-stimulated gene response and cytokine release.J Immunol2015
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Collaborators

Jan Koster
Amsterdam University Medical Centers location AMC
Co-authored papers 19
Andr?? S Bachmann
College of Human Medicine, Michigan State University
Co-authored papers 17
Thomas Wurdinger
Co-authored papers 5
Dana-Lynn T Koomoa
University of Hawai'i at Hilo
Co-authored papers 4
Jan J Molenaar
Co-authored papers 2
C Ellen van der Schoot
Co-authored papers 2
Alexander P J Vlaar
University of Amsterdam
Co-authored papers 2
Thomas Klingebiel
Co-authored papers 1
Danny A Zwijnenburg
Co-authored papers 1
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 1
Angelo L Vescovi
IRCCS Casa Sollievo della Sofferenza, University of Milano-Bicocca
Co-authored papers 1
Sandra Goetze
ETH Zurich
Co-authored papers 1
Leonora Balaj
Massachusetts General Hospital
Co-authored papers 1
Gerald W Dorn
Co-authored papers 1
Tamas Borsics
Cancer Research Center of Hawaii, University of Hawaii at Manoa
Co-authored papers 1
Jaap Jan Zwaginga
Co-authored papers 1
Kenneth Wester
Uppsala University
Co-authored papers 1
Daphne C Thijssen-Timmer
Co-authored papers 1
Ingrid ÿra
Co-authored papers 1
Sjoert B G Jansen
Co-authored papers 1
Sander M Houten
Co-authored papers 1
Emma Lundberg (CM4AI)
Stanford University
Co-authored papers 1
Nathanael S Gray
Harvard Medical School
Co-authored papers 1
Release 1.2