Author details

Full Name

Thomas M Hyde

Affiliation

ORCID

Career Start Year

1983

Papers

270

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37915216	Recapitulation of Perturbed Striatal Gene Expression Dynamics of Donors' Brains With Ventral Forebrain Organoids Derived From the Same Individuals With Schizophrenia.	Am J Psychiatry	2024
36729133	Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex.	Acta Neuropathol	2023
37831723	Investigating trait variability of gene co-expression network architecture in brain by controlling for genomic risk of schizophrenia.	PLoS Genet	2023
37790540	Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci.	medRxiv	2023
37786720	Dopamine and schizophrenia from bench to bedside: Discovery of a striatal co-expression risk gene set that predicts in vivo measures of striatal function.	bioRxiv	2023
37961425	Identification of a specific APOE transcript and functional elements associated with Alzheimer's disease.	medRxiv	2023
37404944	Chronic traumatic encephalopathy neuropathologic change is uncommon in men who played amateur American football.	Front Neurol	2023
36824961	Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortex.	bioRxiv	2023
37141410	Deoxyhypusine hydroxylase: A novel therapeutic target differentially expressed in short-term vs long-term survivors of glioblastoma.	Int J Cancer	2023
36702996	Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.	Nat Genet	2023
37392042	Sutton's Law.	Am J Psychiatry	2023
36945630	Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain.	medRxiv	2023
36698068	SUFI: an automated approach to spectral unmixing of fluorescent multiplex images captured in mouse and post-mortem human brain tissues.	BMC Neurosci	2023
37058565	Consensus molecular environment of schizophrenia risk genes in coexpression networks shifting across age and brain regions.	Sci Adv	2023
37172721	Orthogonal approaches required to measure proteasome composition and activity in mammalian brain tissue.	J Biol Chem	2023
36608676	A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan.	Cell Stem Cell	2023
35236118	Genetics and Brain Transcriptomics of Completed Suicide.	Am J Psychiatry	2022
35969790	Deep learning predicts DNA methylation regulatory variants in the human brain and elucidates the genetics of psychiatric disorders.	Proc Natl Acad Sci U S A	2022
36232351	TRIOBP-1 Protein Aggregation Exists in Both Major Depressive Disorder and Schizophrenia, and Can Occur through Two Distinct Regions of the Protein.	Int J Mol Sci	2022
35868859	Variation in TAF1 expression in female carrier induced pluripotent stem cells and human brain ontogeny has implications for adult neostriatum vulnerability in X-linked Dystonia Parkinsonism.	eNeuro	2022
35794479	Molecular landscapes of human hippocampal immature neurons across lifespan.	Nature	2022
35980743	MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression.	JCI Insight	2022
36845993	Differential expression of <i>NPAS4</i> in the dorsolateral prefrontal cortex following opioid overdose.	Drug Alcohol Depend Rep	2022
35260864	Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways.	Nat Neurosci	2022
35236959	Molecular phenotypes associated with antipsychotic drugs in the human caudate nucleus.	Mol Psychiatry	2022
34582785	Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain.	Neuron	2021
33667780	Epigenome-wide study of brain DNA methylation following acute opioid intoxication.	Drug Alcohol Depend	2021
33771989	P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression.	Nature Communications	2021
33558695	Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex.	Nat Neurosci	2021
33603232	Publisher Correction: Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex.	Nat Neurosci	2021
33649454	Single molecule in situ hybridization reveals distinct localizations of schizophrenia risk-related transcripts SNX19 and AS3MT in human brain.	Mol Psychiatry	2021
32602773	Characterizing the dynamic and functional DNA methylation landscape in the developing human cortex.	Epigenetics	2021
34899570	Suicide in Older Adult Men Is Not Related to a Personal History of Participation in Football.	Front Neurol	2021
34475392	Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia risk.	Nat Commun	2021
30635639	Schizophrenia risk variants influence multiple classes of transcripts of sorting nexin 19 (SNX19).	Mol Psychiatry	2020
32433545	Cannabinoid receptor CNR1 expression and DNA methylation in human prefrontal cortex, hippocampus and caudate in brain development and schizophrenia.	Transl Psychiatry	2020
31852722	Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation.	Genome Res	2020
31695164	Long-read sequencing reveals the complex splicing profile of the psychiatric risk gene CACNA1C in human brain.	Mol Psychiatry	2020
31811028	NURR1 and ERR1 Modulate the Expression of Genes of a <i>DRD2</i> Coexpression Network Enriched for Schizophrenia Risk.	J Neurosci	2020
32446240	Generation of four postmortem dura-derived iPS cell lines from four control individuals with genotypic and brain-region-specific transcriptomic data available through the BrainSEQ consortium.	Stem Cell Res	2020
32383753	dotdotdot: an automated approach to quantify multiplex single molecule fluorescent in situ hybridization (smFISH) images in complex tissues.	Nucleic Acids Research	2020
33256444	Association of Missense Mutation in FOLH1 With Decreased NAAG Levels and Impaired Working Memory Circuitry and Cognition.	Am J Psychiatry	2020
32836031	Sex differences in the transcription of glutamate transporters in major depression and suicide.	J Affect Disord	2020
30478419	Identification and prioritization of gene sets associated with schizophrenia risk by co-expression network analysis in human brain.	Mol Psychiatry	2020
30131587	Developmental effects of maternal smoking during pregnancy on the human frontal cortex transcriptome.	Mol Psychiatry	2020
30712078	Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer's disease.	Acta Neuropathol	2019
31644530	African-American and Caucasian participation in postmortem human brain donation for neuropsychiatric research.	PLoS One	2019
31554518	Divergent neuronal DNA methylation patterns across human cortical development reveal critical periods and a unique role of CpH methylation.	Genome Biol	2019
30600091	Association of a Noncoding RNA Postmortem With Suicide by Violent Means and InÂ Vivo With Aggressive Phenotypes.	Biol Psychiatry	2019
30973874	Somatic LINE-1 retrotransposition in cortical neurons and non-brain tissues of Rett patients and healthy individuals.	PLoS Genetics	2019