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Author Details

Caroline C Friedel
Institute of Informatics, Ludwig-Maximilians-Universitat Munchen
2005
74
30
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36727434P-TEFb promotes cell survival upon p53 activation by suppressing intrinsic apoptosis pathway.Nucleic Acids Res2023
37524699The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes.Nat Commun2023
37811895Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release.Nucleic Acids Res2023
37456509RegCFinder: targeted discovery of genomic subregions with differential read density.Bioinform Adv2023
37289084The Cytomegalovirus M35 Protein Directly Binds to the Interferon-β Enhancer and Modulates Transcription of <i>Ifnb1</i> and Other IRF3-Driven Genes.J Virol2023
37172056Decoding murine cytomegalovirus.PLoS Pathog2023
37093003HSV-1 Infection Induces a Downstream Shift of Promoter-Proximal Pausing for Host Genes.J Virol2023
36534279Computational Integration of HSV-1 Multi-omics Data.Methods Mol Biol2023
35891501Women in the European Virus Bioinformatics Center.Viruses2022
36279270HSV-1 and influenza infection induce linear and circular splicing of the long NEAT1 isoform.PLoS One2022
36104565CDK11 regulates pre-mRNA splicing by phosphorylation of SF3B1.Nature2022
33148793Dissecting Herpes Simplex Virus 1-Induced Host Shutoff at the RNA Level.J Virol2021
33684133Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation.PLoS Genet2021
33514835Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics.Commun Biol2021
33637528Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity.Sci Adv2021
34383492iBRET Screen of the ABCD1 Peroxisomal Network and Mutation-Induced Network Perturbations.J Proteome Res2021
34272227OAS1/RNase L executes RIG-I ligand-dependent tumor cell apoptosis.Sci Immunol2021
32112058Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2.Nat Neurosci2020
31941886Herpes simplex virus blocks host transcription termination via the bimodal activities of ICP27.Nat Commun2020
32556167Watchdog 2.0: New developments for reusability, reproducibility, and workflow execution.Gigascience2020
30476274MIR sequences recruit zinc finger protein ZNF768 to expressed genes.Nucleic Acids Res2019
31843014Correction to: Immunostimulatory RNA leads to functional reprogramming of myeloid-derived suppressor cells in pancreatic cancer.J Immunother Cancer2019
31694706Immunostimulatory RNA leads to functional reprogramming of myeloid-derived suppressor cells in pancreatic cancer.J Immunother Cancer2019
31347271CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genes.EMBO Rep2019
31126966Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.J Exp Med2019
30952620Gene signatures of quiescent glioblastoma cells reveal mesenchymal shift and interactions with niche microenvironment.EBioMedicine2019
30824372P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic Stress.Mol Cell2019
30548142Comprehensive analysis of nuclear export of herpes simplex virus type 1 tegument proteins and their Epstein-Barr virus orthologs.Traffic2019
29534677Watchdog - a workflow management system for the distributed analysis of large-scale experimental data.BMC Bioinformatics2018
29579120HSV-1-induced disruption of transcription termination resembles a cellular stress response but selectively increases chromatin accessibility downstream of genes.PLoS Pathog2018
29578509Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation.J Vis Exp2018
29089033Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection.Genome Biol2017
28135292Prediction of Poly(A) Sites by Poly(A) Read Mapping.PLoS One2017
28423325Rapid Genome-wide Recruitment of RNA Polymerase II Drives Transcription, Splicing, and Translation Events during T Cell Responses.Cell Rep2017
28490802Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of small molecule inhibitor JQ1.Sci Rep2017
27845394Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration.Sci Rep2016
25989971Widespread disruption of host transcription termination in HSV-1 infection.Nat Commun2015
26463011The Hepatitis E virus intraviral interactome.Sci Rep2015
26183718p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) Analyses.Mol Cell Proteomics2015
26170170RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.Nat Commun2015
25928589ContextMap 2: fast and accurate context-based RNA-seq mapping.BMC Bioinformatics2015
23708002β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments.Nat Cell Biol2013
23832230Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis.Nucleic Acids Res2013
23940809Clonal expansion analysis of transposon insertions by high-throughput sequencing identifies candidate cancer genes in a PiggyBac mutagenesis screen.PLoS One2013
240254604-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response.RNA Biol2013
23996253Computational analysis of virus-host interactomes.Methods Mol Biol2013
24019895Mining RNA-seq data for infections and contaminations.PLoS One2013
23963265Metabolic labeling of newly transcribed RNA for high resolution gene expression profiling of RNA synthesis, processing and decay in cell culture.J Vis Exp2013
23950709A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication.PLoS Pathog2013
22242014Genome-wide assessment of AU-rich elements by the AREScore algorithm.PLoS Genet2012
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Collaborators

Ludwig-Maximilians-Universitat Munchen
Co-authored papers 25
University of Edinburgh
Co-authored papers 6
Max von Pettenkofer-Institute, Ludwig-Maximilians-Universitat Munchen
Co-authored papers 5
Helmholtz Center Munich and Center for Integrated Protein Science Munich (CIPSM)
Co-authored papers 4
Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB
Co-authored papers 3
Co-authored papers 3
University Clinic for Swine, University of Veterinary Medicine Vienna
Co-authored papers 3
Max-von-Pettenkofer Institute, Ludwig-Maximilians-University (LMU) Munich
Co-authored papers 3
UK System Immunity Research Institute, Cardiff University
Co-authored papers 3
Ludwig-Maximilians-Universitat Munchen
Co-authored papers 3
Oslo University Hospital
Co-authored papers 2
Center for Biomedical Education and Research (ZBAF), Witten/Herdecke University
Co-authored papers 2
Boehringer Ingelheim RCV GmbH & Co. KG
Co-authored papers 2
Center for the Study of Biological Complexity, Virginia Commonwealth University
Co-authored papers 2
Graduate School of Medicine, The University of Tokyo
Co-authored papers 2
Institute of Developmental Genetics, German Research Center for Environmental Health
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
University of California at San Francisco
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Stanford Center for Biomedical Informatics Research, Stanford University
Co-authored papers 1
Germany Institute of Systems Biology, Shanghai University
Co-authored papers 1
Co-authored papers 1
Institute of Tropical Medicine
Co-authored papers 1
Max Planck Institute for Multidisciplinary Sciences
Co-authored papers 1
university of california los angeles
Co-authored papers 1
Institute of Pathology, University Hospital Salzburg, Paracelsus Medical University
Co-authored papers 1
Co-authored papers 1