Author details

Full Name

Hans Deckmyn

Affiliation

ORCID

Career Start Year

1979

Papers

259

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
33915031	Differential regulation of the platelet GPIb-IX complex by anti-GPIbÎ² antibodies.	Journal of Thrombosis and Haemostasis	2021
32107335	The von Willebrand Factor A1 domain mediates thromboinflammation, aggravating ischemic stroke outcome in mice.	Haematologica	2021
31048352	Structural analysis of ischemic stroke thrombi: histological indications for therapy resistance.	Haematologica	2020
32196558	Antibodies that conformationally activate ADAMTS13 allosterically enhance metalloprotease domain function.	Blood advances	2020
31581346	Crucial Role for Endothelial Cell Î±2Î²1 Integrin Receptor Clustering in Collagen-Induced Angiogenesis.	Anatomical Record	2020
32356859	Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura.	Blood	2020
31989742	Anti-ADAMTS13 autoantibodies in immune-mediated thrombotic thrombocytopenic purpura do not hamper ELISA-based quantification of ADAMTS13 antigen.	Journal of Thrombosis and Haemostasis	2020
32485089	von Willebrand factor increases in experimental cerebral malaria but is not essential for late-stage pathogenesis in mice.	Journal of Thrombosis and Haemostasis	2020
32492725	Glycoprotein VI is not a Functional Platelet Receptor for Fibrin Formed in Plasma or Blood.	Thrombosis and Haemostasis	2020
32917858	Selective inhibition of TGF-Î²1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer.	Nature Communications	2020
32838401	Sickle cell disease and COVID-19: Atypical presentations and favorable outcomes.		2020
31467123	Appropriation of GPIbÎ± from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation.	Haematologica	2020
31099973	von Willebrand factor in experimental malaria-associated acute respiratory distress syndrome.	Journal of Thrombosis and Haemostasis	2019
31710861	Acquired von Willebrand syndrome in patients on long-term left ventricular assist device support: Results of a Belgian center.	Thrombosis Research	2019
30523052	Generation of anti-idiotypic antibodies to detect anti-spacer antibody idiotopes in acute thrombotic thrombocytopenic purpura patients.	Haematologica	2019
30896677	Exposure of von Willebrand Factor on Isolated Hepatocytes Promotes Tethering of Platelets to the Cell Surface.	Transplantation	2019
31249923	Anti-ADAMTS13 Antibodies and a Novel Heterozygous p.R1177Q Mutation in a Case of Pregnancy-Onset Immune-Mediated Thrombotic Thrombocytopenic Purpura.		2018
30397685	Differences in von Willebrand factor function in type 2A von Willebrand disease and left ventricular assist device-induced acquired von Willebrand syndrome.	Research and Practice in Thrombosis and Haemostasis	2018
29972862	Major Changes of von Willebrand Factor Multimer Distribution in Cirrhotic Patients with Stable Disease or Acute Decompensation.	Thrombosis and Haemostasis	2018
30093071	Deletion of GARP on mouse regulatory T cells is not sufficient to inhibit the growth of transplanted tumors.	Cellular Immunology	2018
30235483	Anti-ADAMTS13 Autoantibodies against Cryptic Epitopes in Immune-Mediated Thrombotic Thrombocytopenic Purpura.	Thrombosis and Haemostasis	2018
30280230	Preparation and characterization of large-format macroporous cryogel disks for use in affinity chromatography and biotechnological applications.	Analytical and Bioanalytical Chemistry	2018
30413751	von Willebrand factor deficiency does not influence angiotensin II-induced abdominal aortic aneurysm formation in mice.	Scientific Reports	2018
29763513	Child-onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13.	European Journal of Haematology	2018
29222940	An open conformation of ADAMTS-13 is a hallmark of acute acquired thrombotic thrombocytopenic purpura.	Journal of Thrombosis and Haemostasis	2018
29559479	Oral Bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque-triggered thrombus formation in humans.	Blood	2018
29288565	High and long-term von Willebrand factor expression after Sleeping Beauty transposon-mediated gene therapy in a mouse model of severe von Willebrand disease.	Journal of Thrombosis and Haemostasis	2018
29203584	Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets.	Blood	2018
31249951	Functional Genomics for the Identification of Modulators of Platelet-Dependent Thrombus Formation.		2018
28254814	Long-Term Prevention of Congenital Thrombotic Thrombocytopenic Purpura in ADAMTS13 Knockout Mice by Sleeping Beauty Transposon-Mediated Gene Therapy.	Arteriosclerosis, Thrombosis, and Vascular Biology	2017
28591212	Reduced ADAMTS13 levels in patients with acute and chronic cerebrovascular disease.	PLoS One	2017
28981198	Amplified endogenous plasmin activity resolves acute thrombotic thrombocytopenic purpura in mice.	Journal of Thrombosis and Haemostasis	2017
28696508	Neutrophil extracellular traps in ischemic stroke thrombi.	Annals of Neurology	2017
28470771	Development and screening of epoxy-spacer-phage cryogels for affinity chromatography: Enhancing the binding capacity.	Journal of Separation Science	2017
28011677	-acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura.	Blood	2017
28278197	The role of platelet and endothelial GARP in thrombosis and hemostasis.	PLoS ONE	2017
26581428	ADAMTS13 and anti-ADAMTS13 autoantibodies in thrombotic thrombocytopenic purpura - current perspectives and new treatment strategies.	Expert Review of Hematology	2016
26929275	ADAMTS13-mediated thrombolysis of t-PA-resistant occlusions in ischemic stroke in mice.	Blood	2016
27188532	Platelet sequestration and activation during GalTKO.hCD46 pig lung perfusion by human blood is primarily mediated by GPIb, GPIIb/IIIa, and von Willebrand Factor.	Xenotransplantation	2016
27479501	Generation of Anti-Murine ADAMTS13 Antibodies and Their Application in a Mouse Model for Acquired Thrombotic Thrombocytopenic Purpura.	PLoS ONE	2016
27470988	Inhibition of Thrombin-Activatable Fibrinolysis Inhibitor and Plasminogen Activator Inhibitor-1 Reduces Ischemic Brain Damage in Mice.	Stroke	2016
25988848	Desmopressin treatment improves platelet function under flow in patients with postoperative bleeding.	Journal of Thrombosis and Haemostasis	2015
25931511	Choline Transporter-Like Protein-2: New von Willebrand Factor-Binding Partner Involved in Antibody-Mediated Neutrophil Activation and Transfusion-Related Acute Lung Injury.	Arteriosclerosis, Thrombosis, and Vascular Biology	2015
25442981	The novel ADAMTS13-p.D187H mutation impairs ADAMTS13 activity and secretion and contributes to thrombotic thrombocytopenic purpura in mice.	Journal of Thrombosis and Haemostasis	2015
25904061	Platelets from flowing blood attach to the inflammatory chemokine CXCL16 expressed in the endothelium of the human vessel wall.	Thrombosis and Haemostasis	2015
26176854	Artificial MiRNA Knockdown of Platelet Glycoprotein lbÎ±: A Tool for Platelet Gene Silencing.	PLoS ONE	2015
26391536	Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13.	Journal of Thrombosis and Haemostasis	2015
26209660	Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice.	Blood	2015
24628649	Pig-to-baboon liver xenoperfusion utilizing GalTKO.hCD46 pigs and glycoprotein Ib blockade.	Xenotransplantation	2014
24550384	Single particle tracking of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type-1 repeats) molecules on endothelial von Willebrand factor strings.	Journal of Biological Chemistry	2014