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Author Details

Sjors H W Scheres
Medical Research Council Laboratory of Molecular Biology
2001
126
66
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38030728Disease-specific tau filaments assemble via polymorphic intermediates.Nature2024
38073060Tau and neurodegeneration.Cytoskeleton (Hoboken)2024
36611124Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains.Acta Neuropathol2023
37758888Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids.Nature2023
37798679Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.Acta Neuropathol Commun2023
37613592Structures, Distributions, and Conformations of SARS-CoV-2 Spike Proteins on Intact Virions by Cryo-EM and Cryo-ET.Microsc Microanal2023
37506202Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.Sci Adv2023
37292681Automated model building and protein identification in cryo-EM maps.bioRxiv2023
37351604Mutation â¿¿K281 in MAPT causes Pick's disease.Acta Neuropathol2023
37143123Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy.Acta Neuropathol Commun2023
37337995Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.FEBS Open Bio2023
37167969Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains.Neuron2023
37330290Cryo-EM Structures of Chronic Traumatic Encephalopathy Tau Filaments with PET Ligand Flortaucipir.J Mol Biol2023
37162924Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold.bioRxiv2023
35025654Cryo-EM structures of amyloid-β 42 filaments from human brains.Science2022
36468689A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0.Elife2022
36108674Structures of α-synuclein filaments from human brains with Lewy pathology.Nature2022
36278863Sample preparation in single particle cryo-EM: general discussion.Faraday Discuss2022
35868264The next decade of protein structure.Cell2022
36285779Pushing the limits in single particle cryo-EM: general discussion.Faraday Discuss2022
36254744Map/model validation and machine learning in EM: general discussion.Faraday Discuss2022
36282233Tomographic analysis, CLEM: general discussion.Faraday Discuss2022
35913272High-throughput cryo-EM structure determination of amyloids.Faraday Discuss2022
35244536Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.Elife2022
33368003Multi-body Refinement of Cryo-EM Images in RELION.Methods Mol Biol2021
33830331Correction to: Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.Acta Neuropathol2021
33548114Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy.FEBS Open Bio2021
33520243Exploiting prior knowledge about biological macromolecules in cryo-EM structure determination.IUCrJ2021
33723967Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.Acta Neuropathol2021
34588692Structure-based classification of tauopathies.Nature2021
34783343New tools for automated cryo-EM single-particle analysis in RELION-4.0.Biochem J2021
33433876Tau Protein and Frontotemporal Dementias.Adv Exp Med Biol2021
32165583Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in <i>Drosophila</i>.Science2020
32050258Novel tau filament fold in corticobasal degeneration.Nature2020
32038040Amyloid structure determination in RELION-3.1.Acta Crystallogr D Struct Biol2020
33277481Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.Nat Commun2020
32805734Structures and distributions of SARS-CoV-2 spike proteins on intact virions.Nature2020
32603876Cryo-EM structures of tau filaments.Curr Opin Struct Biol2020
32148853Estimation of high-order aberrations and anisotropic magnification from cryo-EM data sets in <i>RELION</i>-3.1.IUCrJ2020
32461689Structures of α-synuclein filaments from multiple system atrophy.Nature2020
30720432Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.Elife2019
31264960Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule.Elife2019
30713699A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis.IUCrJ2019
30894745Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.Nature2019
29307484Atomic Structure of Type VI Contractile Sheath from Pseudomonas aeruginosa.Structure2018
30158706Structures of filaments from Pick's disease reveal a novel tau protein fold.Nature2018
29856314Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION.Elife2018
30886056Distinct Conformers of Assembled Tau in Alzheimer's and Pick's Diseases.Cold Spring Harb Symp Quant Biol2018
30412051New tools for automated high-resolution cryo-EM structure determination in RELION-3.Elife2018
30276465Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.Acta Neuropathol2018
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Collaborators

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Co-authored papers 7
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Co-authored papers 3
Institute of Structural and Molecular Biology, University of London
Co-authored papers 3
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University of Science and Technology of China
Co-authored papers 3
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
Medical Research Council
Co-authored papers 2
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
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Co-authored papers 1
Frederick National Laboratory for Cancer Research, Inc.
Co-authored papers 1
University of Dundee
Co-authored papers 1
McMaster University
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Columbia University
Co-authored papers 1
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Bio21 Molecular Science and Biotechnology Institute, University of Melbourne
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Leibniz-Institut fur Virologie (LIV)
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Research Unit Analytical Pathology, German Research Center for Environmental Health
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The State University of New Jersey
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The Francis Crick Institute
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Indiana University School of Medicine
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Institute for Quantitative Biomedicine, State University of New Jersey
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