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Author Details
Full Name
Sjors H W Scheres
Affiliation
Medical Research Council Laboratory of Molecular Biology
ORCID
Career Start Year
2001
Papers
126
H Index
66
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
38030728
Disease-specific tau filaments assemble via polymorphic intermediates.
Nature
2024
38073060
Tau and neurodegeneration.
Cytoskeleton (Hoboken)
2024
36611124
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol
2023
37758888
Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids.
Nature
2023
37798679
Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.
Acta Neuropathol Commun
2023
37613592
Structures, Distributions, and Conformations of SARS-CoV-2 Spike Proteins on Intact Virions by Cryo-EM and Cryo-ET.
Microsc Microanal
2023
37506202
Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv
2023
37292681
Automated model building and protein identification in cryo-EM maps.
bioRxiv
2023
37351604
Mutation â¿¿K281 in MAPT causes Pick's disease.
Acta Neuropathol
2023
37143123
Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy.
Acta Neuropathol Commun
2023
37337995
Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
FEBS Open Bio
2023
37167969
Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains.
Neuron
2023
37330290
Cryo-EM Structures of Chronic Traumatic Encephalopathy Tau Filaments with PET Ligand Flortaucipir.
J Mol Biol
2023
37162924
Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold.
bioRxiv
2023
35025654
Cryo-EM structures of amyloid-β 42 filaments from human brains.
Science
2022
36468689
A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0.
Elife
2022
36108674
Structures of α-synuclein filaments from human brains with Lewy pathology.
Nature
2022
36278863
Sample preparation in single particle cryo-EM: general discussion.
Faraday Discuss
2022
35868264
The next decade of protein structure.
Cell
2022
36285779
Pushing the limits in single particle cryo-EM: general discussion.
Faraday Discuss
2022
36254744
Map/model validation and machine learning in EM: general discussion.
Faraday Discuss
2022
36282233
Tomographic analysis, CLEM: general discussion.
Faraday Discuss
2022
35913272
High-throughput cryo-EM structure determination of amyloids.
Faraday Discuss
2022
35244536
Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife
2022
33368003
Multi-body Refinement of Cryo-EM Images in RELION.
Methods Mol Biol
2021
33830331
Correction to: Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol
2021
33548114
Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy.
FEBS Open Bio
2021
33520243
Exploiting prior knowledge about biological macromolecules in cryo-EM structure determination.
IUCrJ
2021
33723967
Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol
2021
34588692
Structure-based classification of tauopathies.
Nature
2021
34783343
New tools for automated cryo-EM single-particle analysis in RELION-4.0.
Biochem J
2021
33433876
Tau Protein and Frontotemporal Dementias.
Adv Exp Med Biol
2021
32165583
Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in <i>Drosophila</i>.
Science
2020
32050258
Novel tau filament fold in corticobasal degeneration.
Nature
2020
32038040
Amyloid structure determination in RELION-3.1.
Acta Crystallogr D Struct Biol
2020
33277481
Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun
2020
32805734
Structures and distributions of SARS-CoV-2 spike proteins on intact virions.
Nature
2020
32603876
Cryo-EM structures of tau filaments.
Curr Opin Struct Biol
2020
32148853
Estimation of high-order aberrations and anisotropic magnification from cryo-EM data sets in <i>RELION</i>-3.1.
IUCrJ
2020
32461689
Structures of α-synuclein filaments from multiple system atrophy.
Nature
2020
30720432
Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife
2019
31264960
Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule.
Elife
2019
30713699
A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis.
IUCrJ
2019
30894745
Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.
Nature
2019
29307484
Atomic Structure of Type VI Contractile Sheath from Pseudomonas aeruginosa.
Structure
2018
30158706
Structures of filaments from Pick's disease reveal a novel tau protein fold.
Nature
2018
29856314
Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION.
Elife
2018
30886056
Distinct Conformers of Assembled Tau in Alzheimer's and Pick's Diseases.
Cold Spring Harb Symp Quant Biol
2018
30412051
New tools for automated high-resolution cryo-EM structure determination in RELION-3.
Elife
2018
30276465
Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol
2018
1 - 50 of 126
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