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Author Details
Full Name
Manu Anantpadma
Affiliation
Boston University
ORCID
Career Start Year
2009
Papers
31
H Index
18
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
33907750
Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo.
bioRxiv
2022
35357134
Evaluation of Phenol-Substituted Diphyllin Derivatives as Selective Antagonists for Ebola Virus Entry.
ACS Infect Dis
2022
35992305
Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization.
iScience
2022
36007601
Ligand-based design of peptide entry inhibitors targeting the endosomal receptor binding site of filoviruses.
Antiviral Res
2022
33445537
Automation of Infectious Focus Assay for Determination of Filovirus Titers and Direct Comparison to Plaque and TCID<sub>50</sub> Assays.
Microorganisms
2021
33705865
Identification of filovirus entry inhibitors targeting the endosomal receptor NPC1 binding site.
Antiviral Res
2021
34260076
Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection.
EMBO J
2021
32490678
Discovery and Structural Optimization of 4-(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections.
J Med Chem
2020
32886512
Screening and Reverse-Engineering of Estrogen Receptor Ligands as Potent Pan-Filovirus Inhibitors.
J Med Chem
2020
32682926
Pyronaridine tetraphosphate efficacy against Ebola virus infection in guinea pig.
Antiviral Res
2020
32870648
High-Throughput Screening Assay to Identify Small Molecule Inhibitors of Marburg Virus VP40 Protein.
ACS Infect Dis
2020
30729228
Ebola Virus Bayesian Machine Learning Models Enable New in Vitro Leads.
ACS Omega
2019
31751347
Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection.
PLoS Negl Trop Dis
2019
31101988
The Natural Product Eugenol Is an Inhibitor of the Ebola Virus In Vitro.
Pharm Res
2019
29584652
Identification of Ellagic Acid from Plant Rhodiola rosea L. as an Anti-Ebola Virus Entry Inhibitor.
Viruses
2018
29860496
Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates.
J Infect Dis
2018
30144461
Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.
Antiviral Res
2018
30550789
Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication.
Cell
2018
30513600
Identification of Diaryl-Quinoline Compounds as Entry Inhibitors of Ebola Virus.
Viruses
2018
30335906
Phenotypic Prioritization of Diphyllin Derivatives That Block Filoviral Cell Entry by Vacuolar (H<sup>+</sup> )-ATPase Inhibition.
ChemMedChem
2018
28601947
Mechanisms of Filovirus Entry.
Curr Top Microbiol Immunol
2017
27001363
Treatment of blood with a pathogen reduction technology using ultraviolet light and riboflavin inactivates Ebola virus in vitro.
Transfusion
2016
27161622
Large-Scale Screening and Identification of Novel Ebola Virus and Marburg Virus Entry Inhibitors.
Antimicrob Agents Chemother
2016
27185801
Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State.
Antimicrob Agents Chemother
2016
25865894
An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.
Cell Rep
2015
26562011
Interferon-γ Inhibits Ebola Virus Infection.
PLoS Pathog
2015
24495995
In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity.
J Mol Biol
2014
22114132
siRNA-mediated suppression of Japanese encephalitis virus replication in cultured cells and mice.
J Antimicrob Chemother
2012
20962101
Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins.
J Virol
2011
20299495
Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptide-conjugated morpholino oligomer.
J Antimicrob Chemother
2010
19264640
La protein binds the predicted loop structures in the 3' non-coding region of Japanese encephalitis virus genome: role in virus replication.
J Gen Virol
2009
1 - 31 of 31
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