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Author Details

Manu Anantpadma
Boston University
2009
31
18
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33907750Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo.bioRxiv2022
35357134Evaluation of Phenol-Substituted Diphyllin Derivatives as Selective Antagonists for Ebola Virus Entry.ACS Infect Dis2022
35992305Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization.iScience2022
36007601Ligand-based design of peptide entry inhibitors targeting the endosomal receptor binding site of filoviruses.Antiviral Res2022
33445537Automation of Infectious Focus Assay for Determination of Filovirus Titers and Direct Comparison to Plaque and TCID<sub>50</sub> Assays.Microorganisms2021
33705865Identification of filovirus entry inhibitors targeting the endosomal receptor NPC1 binding site.Antiviral Res2021
34260076Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection.EMBO J2021
32490678Discovery and Structural Optimization of 4-(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections.J Med Chem2020
32886512Screening and Reverse-Engineering of Estrogen Receptor Ligands as Potent Pan-Filovirus Inhibitors.J Med Chem2020
32682926Pyronaridine tetraphosphate efficacy against Ebola virus infection in guinea pig.Antiviral Res2020
32870648High-Throughput Screening Assay to Identify Small Molecule Inhibitors of Marburg Virus VP40 Protein.ACS Infect Dis2020
30729228Ebola Virus Bayesian Machine Learning Models Enable New in Vitro Leads.ACS Omega2019
31751347Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection.PLoS Negl Trop Dis2019
31101988The Natural Product Eugenol Is an Inhibitor of the Ebola Virus In Vitro.Pharm Res2019
29584652Identification of Ellagic Acid from Plant Rhodiola rosea L. as an Anti-Ebola Virus Entry Inhibitor.Viruses2018
29860496Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates.J Infect Dis2018
30144461Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.Antiviral Res2018
30550789Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication.Cell2018
30513600Identification of Diaryl-Quinoline Compounds as Entry Inhibitors of Ebola Virus.Viruses2018
30335906Phenotypic Prioritization of Diphyllin Derivatives That Block Filoviral Cell Entry by Vacuolar (H<sup>+</sup> )-ATPase Inhibition.ChemMedChem2018
28601947Mechanisms of Filovirus Entry.Curr Top Microbiol Immunol2017
27001363Treatment of blood with a pathogen reduction technology using ultraviolet light and riboflavin inactivates Ebola virus in vitro.Transfusion2016
27161622Large-Scale Screening and Identification of Novel Ebola Virus and Marburg Virus Entry Inhibitors.Antimicrob Agents Chemother2016
27185801Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State.Antimicrob Agents Chemother2016
25865894An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.Cell Rep2015
26562011Interferon-γ Inhibits Ebola Virus Infection.PLoS Pathog2015
24495995In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity.J Mol Biol2014
22114132siRNA-mediated suppression of Japanese encephalitis virus replication in cultured cells and mice.J Antimicrob Chemother2012
20962101Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins.J Virol2011
20299495Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptide-conjugated morpholino oligomer.J Antimicrob Chemother2010
19264640La protein binds the predicted loop structures in the 3' non-coding region of Japanese encephalitis virus genome: role in virus replication.J Gen Virol2009
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Collaborators

Boston University
Co-authored papers 27
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Co-authored papers 6
Trudeau Institute
Co-authored papers 5
Washington University School of Medicine
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College of Medicine, University of Florida
Co-authored papers 2
Blavatnik Institute, Harvard Medical School
Co-authored papers 2
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Co-authored papers 2
Harvard Medical School
Co-authored papers 2
Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 2
Purdue University
Co-authored papers 2
J. David Gladstone Institutes
Co-authored papers 2
H. Lee Moffitt Cancer Center and Research Institute
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Washington University School of Medicine
Co-authored papers 1
Northwestern University Feinberg School of Medicine
Co-authored papers 1
Texas Biomedical Research Institute
Co-authored papers 1
Institute for Life and Medical Sciences, Kyoto University
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Washington University School of Medicine
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