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Author Details

Kiran Musunuru
Perelman School of Medicine at the University of Pennsylvania
1994
166
55
PMIDPaper TitleJournal TitlePublished Year
37142705Efficient prime editing in mouse brain, liver and heart with dual AAVs.Nat Biotechnol2024
37922902A base editing strategy using mRNA-LNPs for in vivo correction of the most frequent phenylketonuria variant.HGG Adv2024
37142705Efficient prime editing in mouse brain, liver and heart with dual AAVs.Nat Biotechnol2024
37922902A base editing strategy using mRNA-LNPs for in vivo correction of the most frequent phenylketonuria variant.HGG Adv2024
36454456An Overview of Genome Editing in Cardiovascular and Metabolic Diseases.Adv Exp Med Biol2023
35388882CRISPR and cardiovascular diseases.Cardiovasc Res2023
37589141Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes.Arterioscler Thromb Vasc Biol2023
37924808Efficient in vivo prime editing corrects the most frequent phenylketonuria variant, associated with high unmet medical need.Am J Hum Genet2023
37814839Playing the genetic lottery: an interview with Kiran Musunuru.Dis Model Mech2023
37339310Translational Justice in Human Gene Editing: Bringing End User Engagement and Policy Together.Am J Bioeth2023
37314680Base Editing and Prime Editing: Potential Therapeutic Options for Rare and Common Diseases.BioDrugs2023
37188660GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy.Nat Commun2023
37301931Rapid and definitive treatment of phenylketonuria in variant-humanized mice with corrective editing.Nat Commun2023
37165871Evaluating the Contribution of Cell Type-Specific Alternative Splicing to Variation in Lipid Levels.Circ Genom Precis Med2023
36454456An Overview of Genome Editing in Cardiovascular and Metabolic Diseases.Adv Exp Med Biol2023
37292627Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes.bioRxiv2023
37589141Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes.Arterioscler Thromb Vasc Biol2023
37924808Efficient in vivo prime editing corrects the most frequent phenylketonuria variant, associated with high unmet medical need.Am J Hum Genet2023
37814839Playing the genetic lottery: an interview with Kiran Musunuru.Dis Model Mech2023
35388882CRISPR and cardiovascular diseases.Cardiovasc Res2023
37292627Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes.bioRxiv2023
37188660GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy.Nat Commun2023
37314680Base Editing and Prime Editing: Potential Therapeutic Options for Rare and Common Diseases.BioDrugs2023
37339310Translational Justice in Human Gene Editing: Bringing End User Engagement and Policy Together.Am J Bioeth2023
37301931Rapid and definitive treatment of phenylketonuria in variant-humanized mice with corrective editing.Nat Commun2023
37165871Evaluating the Contribution of Cell Type-Specific Alternative Splicing to Variation in Lipid Levels.Circ Genom Precis Med2023
35021064Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins.Cell2022
35902773Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors.Nat Biomed Eng2022
35931809Publisher Correction: Efficient in vivo base editing via single adenoassociated viruses with size-optimized genomes encoding compact adenine base editors.Nat Biomed Eng2022
34981785Moving toward genome-editing therapies for cardiovascular diseases.J Clin Invest2022
34907967Therapeutic application of genome editing in dyslipidemia.Curr Opin Lipidol2022
35021064Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins.Cell2022
35081256Adipocyte-Specific Modulation of KLF14 Expression in Mice Leads to Sex-Dependent Impacts on Adiposity and Lipid Metabolism.Diabetes2022
35242827<i>BRCA1/2</i> Mutations and Cardiovascular Function in Breast Cancer Survivors.Front Cardiovasc Med2022
35902773Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors.Nat Biomed Eng2022
35931809Publisher Correction: Efficient in vivo base editing via single adenoassociated viruses with size-optimized genomes encoding compact adenine base editors.Nat Biomed Eng2022
34981785Moving toward genome-editing therapies for cardiovascular diseases.J Clin Invest2022
35242827<i>BRCA1/2</i> Mutations and Cardiovascular Function in Breast Cancer Survivors.Front Cardiovasc Med2022
34907967Therapeutic application of genome editing in dyslipidemia.Curr Opin Lipidol2022
35081256Adipocyte-Specific Modulation of KLF14 Expression in Mice Leads to Sex-Dependent Impacts on Adiposity and Lipid Metabolism.Diabetes2022
33234004Treating Coronary Artery Disease: Beyond Statins, Ezetimibe, and PCSK9 Inhibition.Annu Rev Med2021
34012082In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.Nature2021
33958126Chronobiology of Natriuretic Peptides and Blood Pressure in Lean and Obese Individuals.J Am Coll Cardiol2021
33740446Active learning-based STEM education for in-person and online learning.Cell2021
33529599Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes.Cell Stem Cell2021
34257302In utero adenine base editing corrects multi-organ pathology in a lethal lysosomal storage disease.Nat Commun2021
34308436Adenine base editing to treat progeria syndrome and extend the lifespan.J Cardiovasc Aging2021
33234004Treating Coronary Artery Disease: Beyond Statins, Ezetimibe, and PCSK9 Inhibition.Annu Rev Med2021
34406041CRISPR Hits Home in a First-in-Human Study.CRISPR J2021
34861143Detoxifying chemotherapy with genetics-guided stem cell modeling: A personalized affair.Cell Stem Cell2021
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Kelly A Frazer
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Collaborators

Daniel J Rader
Co-authored papers 22
Sekar Kathiresan
Co-authored papers 20
Anna F Dominiczak
Co-authored papers 17
Christopher J O'Donnell
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 14
Nilesh J Samani
Co-authored papers 10
Gudmar Thorleifsson
deCODE genetics/Amgen Inc.
Co-authored papers 10
Kari Stefansson
University of Iceland
Co-authored papers 10
Muredach P Reilly
Vagelos College of Physicians and Surgeons, Columbia University
Co-authored papers 9
Laura Adrienne Cupples
Co-authored papers 9
Rajat M Gupta
Co-authored papers 9
Benjamin F Voight
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 9
Unnur Thorsteinsdottir
University of Iceland
Co-authored papers 9
Mingyao Li
Co-authored papers 9
Heribert Schunkert
Co-authored papers 9
Veikko Salomaa
Co-authored papers 8
David Altshuler
Broad Institute of Harvard and Massachusetts Institute of Technology (MIT)
Co-authored papers 8
Alistair S Hall
Co-authored papers 8
Eric Boerwinkle
Baylor College of Medicine
Co-authored papers 8
Jeanette Erdmann
Co-authored papers 8
Olle Melander
Co-authored papers 8
Christian Hengstenberg
Co-authored papers 8
Hilma Holm
Co-authored papers 8
Robert B Darnell
Co-authored papers 8
Andreas Ziegler
Co-authored papers 7
Candace Guiducci
Broad Institute of MIT and Harvard
Co-authored papers 7
John R Thompson
Co-authored papers 7
Jose M Ordovas
Tufts University
Co-authored papers 7
Gina M Peloso
Co-authored papers 7
Derek T Peters
Duke University Medical Center
Co-authored papers 7
Panos Deloukas
William Harvey Research Institute, Queen Mary University of London
Co-authored papers 6
Release 1.2