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Author Details

Brian Raught
Princess Margaret Cancer Centre, University Health Network
1994
176
63
PMIDPaper TitleJournal TitlePublished Year
37856025Proximity Mapping of Ciliary Proteins by BioID.Methods Mol Biol2024
36755019Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT.Nat Commun2023
37962001MAPL loss dysregulates bile and liver metabolism in mice.EMBO Rep2023
37961297Recruitment of FBXO22 for Targeted Degradation of NSD2.bioRxiv2023
37697435RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.Nucleic Acids Res2023
37735473The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG.Nat Commun2023
37873284Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium.bioRxiv2023
37021547Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity.Haematologica2023
36597481Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors.Heliyon2023
34432599C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.Autophagy2022
35411088Aggresome assembly at the centrosome is driven by CP110-CEP97-CEP290 and centriolar satellites.Nat Cell Biol2022
35668135The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.Nat Cell Biol2022
36505937Erratum: DCAF7 regulates cell proliferation through IRS1-FOXO1 signaling.iScience2022
36248734DCAF7 regulates cell proliferation through IRS1-FOXO1 signaling.iScience2022
36070144Oncohistone interactome profiling uncovers contrasting oncogenic mechanisms and identifies potential therapeutic targets in high grade glioma.Acta Neuropathol2022
36384111ο γ-tubulin complex-dependent pathway suppresses ciliogenesis by promoting cilia disassembly.Cell Rep2022
35921881FASN inhibitor TVB-3166 prevents S-acylation of the spike protein of human coronaviruses.J Lipid Res2022
36089195The in vivo Interaction Landscape of Histones H3.1 and H3.3.Mol Cell Proteomics2022
35269585Proximity Profiling of the CFTR Interaction Landscape in Response to Orkambi.Int J Mol Sci2022
35017685Author Correction: A proximity-dependent biotinylation map of a human cell.Nature2022
34524948Global Proximity Interactome of the Human Macroautophagy Pathway.Autophagy2022
34196309Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.J Clin Invest2021
33683136A SARS-CoV-2 Peptide Spectral Library Enables Rapid, Sensitive Identification of Virus Peptides in Complex Biological Samples.J Proteome Res2021
33617900SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function.J Mol Biol2021
33529165RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.J Clin Invest2021
34404769Listeria exploits IFITM3 to suppress antibacterial activity in phagocytes.Nat Commun2021
34725361The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors.Nat Commun2021
34188192MYC protein interactors in gene transcription and cancer.Nat Rev Cancer2021
34019286Identifying and Validating MYC:Protein Interactors in Pursuit of Novel Anti-MYC Therapies.Methods Mol Biol2021
34128958Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs.J Cell Biol2021
34349110Salmonella effector SopD promotes plasma membrane scission by inhibiting Rab10.Nat Commun2021
33958784A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness.Nat Immunol2021
34285335Loss of Acot12 contributes to NAFLD independent of lipolysis of adipose tissue.Exp Mol Med2021
32535973The long form of pVHL is artifactually modified by serine protease inhibitor AEBSF.Protein Sci2020
33187149Proximal Protein Interaction Landscape of RAS Paralogs.Cancers (Basel)2020
33038334Comparative Super-Resolution Mapping of Basal Feet Reveals a Modular but Distinct Architecture in Primary and Motile Cilia.Dev Cell2020
32891193Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.Am J Hum Genet2020
32747500ARID1a Associates with Lymphoid-Restricted Transcription Factors and Has an Essential Role in T Cell Development.J Immunol2020
32938917Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes.Nat Commun2020
32628020Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.J Proteome Res2020
32763951A Comprehensive, Flexible Collection of SARS-CoV-2 Coding Regions.G3 (Bethesda)2020
32903271Cancer proteome and metabolite changes linked to SHMT2.PLoS One2020
32619424TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate.Cell2020
32814032Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4.Structure2020
32496561LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation.J Cell Biol2020
32269163The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability.Sci Transl Med2020
30644389Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation.Nat Commun2019
31719531ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer.Nat Commun2019
31686052Multiple direct interactions of TBP with the MYC oncoprotein.Nat Struct Mol Biol2019
31660083FKBP4 connects mTORC2 and PI3K to activate the PDK1/Akt-dependent cell proliferation signaling in breast cancer.Theranostics2019
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Collaborators

Anne-Claude Gingras
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 37
Linda Z Penn
University of Toronto
Co-authored papers 14
Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 13
Pak-Kei Chan
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 11
William B Tu
David Geffen School of Medicine, University of California Los Angeles
Co-authored papers 7
Cheryl H Arrowsmith
University of Toronto
Co-authored papers 7
Manpreet Kalkat
Van Andel Institute
Co-authored papers 7
Alexey I Nesvizhskii
University of Michigan ann arbor
Co-authored papers 7
Razqallah Hakem
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 7
Parasvi S Patel
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 6
Anne Hakem
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 6
Dharmendra Dingar
Montreal Heart Institute Montreal Quebec Canada.
Co-authored papers 5
Corey Lourenco
University of Toronto
Co-authored papers 5
Aaron D Schimmer
Princess Margaret Cancer Centre
Co-authored papers 5
Mike Tyers
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 5
Michael F Moran
Hospital for Sick Children, University of Toronto
Co-authored papers 5
Rose Hurren
Princess Margaret Cancer Centre
Co-authored papers 5
Diana Resetca
University of Toronto
Co-authored papers 5
Paul C Boutros
University of California los angeles
Co-authored papers 5
Igor Jurisica
Schroeder Arthritis Institute
Co-authored papers 5
Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 5
Maria Sunnerhagen
Linkoping University
Co-authored papers 5
Jason Moffat
University of Toronto
Co-authored papers 4
Yong Wei
Princess Margaret Cancer Centre, University Health Network, College St
Co-authored papers 4
Brenda J Andrews
University of Toronto
Co-authored papers 4
Patrick G A Pedrioli
Institute of Translational Medicine, Swiss Federal Institute of Technology/ETH Zurich
Co-authored papers 4
Charles Boone
University of Toronto
Co-authored papers 4
Marcela Gronda
Princess Margaret Cancer Centre
Co-authored papers 4
Samah El Ghamrasni
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
John E Dick
Princess Margaret Cancer Centre, University Health Network
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