|
| 36824782 | Distinct biological activity of Lewy body α-Synuclein strain in mice. | Res Sq | 2023 |
| 37703352 | A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury. | Sci Transl Med | 2023 |
| 37745431 | Human iPSC 4R tauopathy model uncovers modifiers of tau propagation. | bioRxiv | 2023 |
| 37651366 | A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy. | J Med Chem | 2023 |
| 37499037 | TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease. | Science | 2023 |
| 37814027 | Author Correction: Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein. | Nat Neurosci | 2023 |
| 37425910 | Genome-wide association study identifies a new susceptibility locus in <i>PLA2G4C</i> for Multiple System Atrophy. | medRxiv | 2023 |
| 37150879 | Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies. | Brain | 2023 |
| 37248338 | Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage. | Nat Neurosci | 2023 |
| 36945566 | O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology. | bioRxiv | 2023 |
| 37169750 | Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson's disease. | NPJ Parkinsons Dis | 2023 |
| 37269953 | Identification of small molecules and related targets that modulate tau pathology in a seeded primary neuron model. | J Biol Chem | 2023 |
| 36809847 | Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD. | Neurobiol Dis | 2023 |
| 36399276 | In Vitro Amplification of Pathogenic Tau Seeds from Neurodegenerative Disease Patient Brains. | Methods Mol Biol | 2023 |
| 36778217 | Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies. | medRxiv | 2023 |
| 36534051 | Microtubule-Stabilizing 1,2,4-Triazolo[1,5-<i>a</i>]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure-Activity Insights. | J Med Chem | 2023 |
| 36456471 | Abundant copathologies of polyglucosan bodies, frontotemporal lobar degeneration with TDP-43 inclusions and ageing-related tau astrogliopathy in a family with a GBE1 mutation. | Neuropathol Appl Neurobiol | 2023 |
| 36864661 | Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated. | Brain | 2023 |
| 35292638 | Tau deposition patterns are associated with functional connectivity in primary tauopathies. | Nat Commun | 2022 |
| 35727707 | Investigating key factors underlying neurodegeneration linked to alpha-synuclein spread. | Neuropathol Appl Neurobiol | 2022 |
| 35568882 | Slow motor neurons resist pathological TDP-43 and mediate motor recovery in the rNLS8 model of amyotrophic lateral sclerosis. | Acta Neuropathol Commun | 2022 |
| 35624093 | Fluent molecular mixing of Tau isoforms in Alzheimer's disease neurofibrillary tangles. | Nat Commun | 2022 |
| 37250748 | Cerebrovascular disease lesions are additive and tied to vascular risk factors and cognitive impairment. | Free Neuropathol | 2022 |
| 36408394 | Manipulation of the diet-microbiota-brain axis in Alzheimer's disease. | Front Neurosci | 2022 |
| 36540894 | Evaluation of blood-based, extracellular vesicles as biomarkers for aging-related TDP-43 pathology. | Alzheimers Dement (Amst) | 2022 |
| 35258081 | Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease. | Brain | 2022 |
| 35256815 | Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue. | Nat Biotechnol | 2022 |
| 35131527 | Modeling the cellular fate of alpha-synuclein aggregates: A pathway to pathology. | Curr Opin Neurobiol | 2022 |
| 34854996 | Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease. | Acta Neuropathol | 2022 |
| 35246269 | Inhibition of CK2 mitigates Alzheimer's tau pathology by preventing NR2B synaptic mislocalization. | Acta Neuropathol Commun | 2022 |
| 35063084 | Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration. | Cell | 2022 |
| 33091110 | α-Synuclein modulates tau spreading in mouse brains. | J Exp Med | 2021 |
| 33644757 | Distinct microglial response against Alzheimer's amyloid and tau pathologies characterized by P2Y12 receptor. | Brain Commun | 2021 |
| 33842063 | Neurofilament Light Chain Related to Longitudinal Decline in Frontotemporal Lobar Degeneration. | Neurol Clin Pract | 2021 |
| 33720852 | LRRK2 Kinase Activity Does Not Alter Cell-Autonomous Tau Pathology Development in Primary Neurons. | J Parkinsons Dis | 2021 |
| 34851693 | AD-linked R47H-<i>TREM2</i> mutation induces disease-enhancing microglial states via AKT hyperactivation. | Sci Transl Med | 2021 |
| 34412701 | Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery. | Acta Neuropathol Commun | 2021 |
| 34819159 | Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro. | Acta Neuropathol Commun | 2021 |
| 34503586 | Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice. | Acta Neuropathol Commun | 2021 |
| 34220490 | Poly (ADP-ribose) Interacts With Phosphorylated α-Synuclein in Post Mortem PD Samples. | Front Aging Neurosci | 2021 |
| 34152475 | TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy. | Acta Neuropathol | 2021 |
| 34108219 | Computational modeling of tau pathology spread reveals patterns of regional vulnerability and the impact of a genetic risk factor. | Sci Adv | 2021 |
| 33971027 | Distinct brain-derived TDP-43 strains from FTLD-TDP subtypes induce diverse morphological TDP-43 aggregates and spreading patterns in vitro and in vivo. | Neuropathol Appl Neurobiol | 2021 |
| 33449993 | The development and convergence of co-pathologies in Alzheimer's disease. | Brain | 2021 |
| 33125873 | High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer's and Non-Alzheimer's Disease Tauopathies. | Neuron | 2021 |
| 33385254 | In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics. | Acta Neuropathol | 2021 |
| 33411523 | Evaluation of the Structure-Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-<i>a</i>]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies. | J Med Chem | 2021 |
| 32317958 | Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia. | Front Aging Neurosci | 2020 |
| 31999351 | Primary Tau Pathology, Not Copathology, Correlates With Clinical Symptoms in PSP and CBD. | J Neuropathol Exp Neurol | 2020 |
| 31899072 | Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult. | Neuron | 2020 |