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Author Details

Frank Brombacher
University of Cape Town
1989
281
71
PMIDPaper TitleJournal TitlePublished Year
36599893IL-4Rα signalling in B cells and T cells play differential roles in acute and chronic atopic dermatitis.Sci Rep2023
37316698Author Correction: IL-4Rα signalling in B cells and T cells play differential roles in acute and chronic atopic dermatitis.Sci Rep2023
37180163Environmental and microbial factors influence affective and cognitive behavior in C57BL/6 sub-strains.Front Immunol2023
37279329Foxp3 and Bcl6 deficiency synergistically induces spontaneous development of atopic dermatitis-like skin disease.Int Immunol2023
34389214Influence of schistosomiasis on host vaccine responses.Trends Parasitol2022
35835714Type 2 immunity: a two-edged sword in schistosomiasis immunopathology.Trends Immunol2022
35418649Author Correction: Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote T<sub>H</sub>2 and inhibit T<sub>H</sub>17 cell polarization.Nat Immunol2022
36789295A recombinant Der p 1-specific allergen-toxin demonstrates superior killing of allergen-reactive IgG<sup>+</sup> hybridomas in comparison to its recombinant allergen-drug conjugate.Immunother Adv2022
36432169Arteannuin-B and (3-Chlorophenyl)-2-Spiroisoxazoline Derivative Exhibit Anti-Inflammatory Effects in LPS-Activated RAW 264.7 Macrophages and BALB/c Mice-Induced Proinflammatory Responses via Downregulation of NF-κB/P38 MAPK Signaling.Molecules2022
36371785The metabolomics of a protein kinase C delta (PKCδ) knock-out mouse model.Metabolomics2022
36063138Interleukin-4 receptor alpha signaling regulates monocyte homeostasis.FASEB J2022
35895506Host-Directed Targeting of LincRNA-MIR99AHG Suppresses Intracellular Growth of <i>Mycobacterium tuberculosis</i>.Nucleic Acid Ther2022
36119114Lyl1-deficiency promotes inflammatory responses and increases mycobacterial burden in response to <i>Mycobacterium tuberculosis</i> infection in mice.Front Immunol2022
33814018n-3 long-chain PUFA promote antibacterial and inflammation-resolving effects in Mycobacterium tuberculosis-infected C3HeB/FeJ mice, dependent on fatty acid status.Br J Nutr2022
35157732Schistosoma mansoni infection induces plasmablast and plasma cell death in the bone marrow and accelerates the decline of host vaccine responses.PLoS Pathog2022
35154068Interleukin-4 Responsive Dendritic Cells Are Dispensable to Host Resistance Against <i>Leishmania mexicana</i> Infection.Front Immunol2022
35084027Intranasally administered S-MGB-364 displays antitubercular activity and modulates the host immune response to Mycobacterium tuberculosis infection.J Antimicrob Chemother2022
33383090Deletion of IL-4Rα signaling on B cells limits hyperresponsiveness depending on antigen load.J Allergy Clin Immunol2021
35387053Respiratory Viral and Bacterial Factors That Influence Early Childhood Asthma.Front Allergy2021
33912039Triptolide Modulates the Expression of Inflammation-Associated lncRNA-PACER and lincRNA-p21 in <i>Mycobacterium tuberculosis</i>-Infected Monocyte-Derived Macrophages.Front Pharmacol2021
33857419Il4ra-independent vaginal eosinophil accumulation following helminth infection exacerbates epithelial ulcerative pathology of HSV-2 infection.Cell Host Microbe2021
33798555IL-4Rα signaling by CD8α<sup>+</sup> dendritic cells contributes to cerebral malaria by enhancing inflammatory, Th1, and cytotoxic CD8<sup>+</sup> T cell responses.J Biol Chem2021
34956183Praziquantel Treatment of <i>Schistosoma mansoni</i> Infected Mice Renders Them Less Susceptible to Reinfection.Front Immunol2021
34739044IL-4i1 Regulation of Immune Protection During Mycobacterium tuberculosis Infection.J Infect Dis2021
34747366Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection.JCI Insight2021
34745105Targeting Molecular Inflammatory Pathways in Granuloma as Host-Directed Therapies for Tuberculosis.Front Immunol2021
34745081Evaluation of Berberine as an Adjunct to TB Treatment.Front Immunol2021
34504860Adjunct n-3 Long-Chain Polyunsaturated Fatty Acid Treatment in Tuberculosis Reduces Inflammation and Improves Anemia of Infection More in C3HeB/FeJ Mice With Low n-3 Fatty Acid Status Than Sufficient n-3 Fatty Acid Status.Front Nutr2021
34795444Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote T<sub>H</sub>2 and inhibit T<sub>H</sub>17 cell polarization.Nat Immunol2021
34132103Inactivation of Interleukin-4 Receptor α Signaling in Myeloid Cells Protects Mice From Angiotensin II/High Salt-Induced Cardiovascular Dysfunction Through Suppression of Fibrotic Remodeling.J Am Heart Assoc2021
33995381Longer-Term Omega-3 LCPUFA More Effective Adjunct Therapy for Tuberculosis Than Ibuprofen in a C3HeB/FeJ Tuberculosis Mouse Model.Front Immunol2021
34220793IL-4-Responsive B Cells Are Detrimental During Chronic Tuberculosis Infection in Mice.Front Immunol2021
34326406Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs.Sci Rep2021
33980132Deletion of N-acetylmuramyl-L-alanine amidases alters the host immune response to <i>Mycobacterium tuberculosis</i> infection.Virulence2021
34367172Identification of Disease-Associated Cryptococcal Proteins Reactive With Serum IgG From Cryptococcal Meningitis Patients.Front Immunol2021
34082319Beneficial effect of long-chain n-3 polyunsaturated fatty acid supplementation on tuberculosis in mice.Prostaglandins Leukot Essent Fatty Acids2021
33164548Myeloid interleukin-4 receptor α is essential in postmyocardial infarction healing by regulating inflammation and fibrotic remodeling.Am J Physiol Heart Circ Physiol2021
32410852IL-4 Receptor-Alpha Signalling of Intestinal Epithelial Cells, Smooth Muscle Cells, and Macrophages Plays a Redundant Role in Oxazolone Colitis.Mediators Inflamm2020
31782803Therapeutic and prophylactic deletion of IL-4Ra-signaling ameliorates established ovalbumin induced allergic asthma.Allergy2020
32066761An ultrasound-based referential of body height-adjusted normal liver organometry in school children from Bokito in rural Cameroon.Sci Rep2020
32039054Inflammatory Dendritic Cells, Regulated by IL-4 Receptor Alpha Signaling, Control Replication, and Dissemination of <i>Leishmania major</i> in Mice.Front Cell Infect Microbiol2020
33193450Immunoglobulin M in Health and Diseases: How Far Have We Come and What Next?Front Immunol2020
33415318Unravelling the unsolved paradoxes of cytokine families in host resistance and susceptibility to Leishmania infection.Cytokine X2020
32606340Investigating the antifibrotic effect of the antiparasitic drug Praziquantel in in vitro and in vivo preclinical models.Sci Rep2020
32971969Omega-3 Fatty Acid and Iron Supplementation Alone, but Not in Combination, Lower Inflammation and Anemia of Infection in <i>Mycobacterium tuberculosis</i>-Infected Mice.Nutrients2020
32709117Can We Harness Immune Responses to Improve Drug Treatment in Leishmaniasis?Microorganisms2020
32931477IL-4Rα signaling in CD4+CD25+FoxP3+ T regulatory cells restrains airway inflammation via limiting local tissue IL-33.JCI Insight2020
30500088IL-4Rα-expressing CD11c<sup>+</sup> cells contribute to driving optimal cellular responses during Schistosoma mansoni infection in mice.J Leukoc Biol2019
31824491Environment and Host-Genetic Determinants in Early Development of Allergic Asthma: Contribution of Fungi.Front Immunol2019
31849991Negative Association of Interleukin-33 Plasma Levels and Schistosomiasis Infection in a Site of Polyparasitism in Rural Cameroon.Front Immunol2019
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Collaborators

International Centre for Genetic Engineering and Biotechnology
Co-authored papers 39
RIKEN Center for Integrative Medical Sciences
Co-authored papers 20
RIKEN Center for Integrative Medical Sciences
Co-authored papers 12
South African Medical Research Council (SAMRC), University of Cape Town
Co-authored papers 12
Massey University
Co-authored papers 11
Center for Integrative Medical Sciences
Co-authored papers 7
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences (IMS)
Co-authored papers 6
Telethon Kids Institute, University of Western Australia
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
Mater Research Institute-UQ, Translational Research Institute
Co-authored papers 5
RIKEN Center for Integrative Medical Sciences
Co-authored papers 5
Saint John's Cancer Institute at Saint John's Health Center
Co-authored papers 5
International Institute of Molecular and Cell Biology in Warsaw
Co-authored papers 4
Institute for Protein Research, Osaka University
Co-authored papers 4
Center for Integrative Medical Sciences
Co-authored papers 4
Center for Integrative Medical Sciences
Co-authored papers 4
The University of Melbourne
Co-authored papers 4
Center for Integrative Medical Sciences
Co-authored papers 4
National Institute of Health Sciences.
Co-authored papers 4
Lydia Becker Institute for Immunology & Infection, University of Manchester
Co-authored papers 4
Mater Research Institute - University of Queensland
Co-authored papers 4
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Cerevance Ltd
Co-authored papers 4
Intractable Disease Research Center, Graduate School of Medicine, Juntendo University
Co-authored papers 4
Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology
Co-authored papers 4
King Abdullah University of Science and Technology (KAUST)
Co-authored papers 4
Karolinska Institute
Co-authored papers 4
South African Medical Research Council (SAMRC), University of Cape Town
Co-authored papers 4