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Author Details

Huiyuan Zhang
Texas Children's Cancer Center
2010
67
29
PMIDPaper TitleJournal TitlePublished Year
37415222Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models.J Transl Med2023
34802040Evaluation of an EZH2 inhibitor in patient-derived orthotopic xenograft models of pediatric brain tumors alone and in combination with chemo- and radiation therapies.Lab Invest2022
35676325Ferroptosis promotes T-cell activation-induced neurodegeneration in multiple sclerosis.Cell Mol Immunol2022
35602963Glycyrrhetinic acid restricts mitochondrial energy metabolism by targeting SHMT2.iScience2022
36550163Publisher Correction: Epigenetic alterations of repeated relapses in patient-matched childhood ependymomas.Nat Commun2022
36335125Epigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas.Nat Commun2022
36298798Increased CD4<sup>+</sup>CD8<sup>+</sup> Double Positive T Cells during Hantaan Virus Infection.Viruses2022
34982959Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function.Immunity2022
35182954Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma.Transl Oncol2022
33184450The SUMOylation of TAB2 mediated by TRIM60 inhibits MAPK/NF-κB activation and the innate immune response.Cell Mol Immunol2021
33931442Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion.Sci Adv2021
34977871NF-κB signaling in inflammation and cancer.MedComm (2020)2021
34719887Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion.Adv Sci (Weinh)2021
33449155Leaving no one behind: tracing every human thymocyte by single-cell RNA-sequencing.Semin Immunopathol2021
33446417T Cell Development: Old Tales Retold By Single-Cell RNA Sequencing.Trends Immunol2021
33358190Corrigendum to "Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors" [Cancer Lett. 493 (2020) 197-206].Cancer Lett2021
32363473Improvement of cerebral ischemia/reperfusion injury by daucosterol palmitate-induced neuronal apoptosis inhibition via PI3K/Akt/mTOR signaling pathway.Metab Brain Dis2020
33117334To TRIM the Immunity: From Innate to Adaptive Immunity.Front Immunol2020
33238123An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets.Cell Rep2020
32891713Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors.Cancer Lett2020
32937153Endogenous Glucocorticoid Signaling Regulates CD8<sup>+</sup> T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment.Immunity2020
32958760Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study.Signal Transduct Target Ther2020
32668241Checkpoint Receptor TIGIT Expressed on Tim-1<sup>+</sup> B Cells Regulates Tissue Inflammation.Cell Rep2020
32839316A noncanonical role of NOD-like receptor NLRP14 in PGCLC differentiation and spermatogenesis.Proc Natl Acad Sci U S A2020
30535776Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments.J Mol Neurosci2019
31693904Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.Cell Rep2019
31676122Epigenetic and transcriptional mechanisms for the regulation of IL-10.Semin Immunol2019
31281318Tertiary Lymphoid Organs in Cancer Immunology: Mechanisms and the New Strategy for Immunotherapy.Front Immunol2019
31190744Andrographolide attenuates bupivacaine-induced cytotoxicity in SH-SY5Y cells through preserving Akt/mTOR activity.Drug Des Devel Ther2019
31100410Small molecule inhibitor agerafenib effectively suppresses neuroblastoma tumor growth in mouse models via inhibiting ERK MAPK signaling.Cancer Lett2019
29293549Macrophage conditioned medium promotes colorectal cancer stem cell phenotype via the hedgehog signaling pathway.PLoS One2018
29899446Induction and transcriptional regulation of the co-inhibitory gene module in T cells.Nature2018
29873323Erratum: Author Correction to: TRIM29 negatively controls antiviral immune response through targeting STING for degradation.Cell Discov2018
30389925Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer.Nat Commun2018
30355798Systems biology-based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma.Sci Transl Med2018
29581886TRIM29 negatively controls antiviral immune response through targeting STING for degradation.Cell Discov2018
29463696Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis.Proc Natl Acad Sci U S A2018
29463553Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models.Clin Cancer Res2018
27564113Novel multiple tyrosine kinase inhibitor ponatinib inhibits bFGF-activated signaling in neuroblastoma cells and suppresses neuroblastoma growth in vivo.Oncotarget2017
28455243The second-generation ALK inhibitor alectinib effectively induces apoptosis in human neuroblastoma cells and inhibits tumor growth in a TH-MYCN transgenic neuroblastoma mouse model.Cancer Lett2017
28430599TAK1 inhibitor 5Z-7-oxozeaenol sensitizes cervical cancer to doxorubicin-induced apoptosis.Oncotarget2017
29152094Xenotransplantation of pediatric low grade gliomas confirms the enrichment of <i>BRAF</i> V600E mutation and preservation of <i>CDKN2A</i> deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma.Oncotarget2017
29149608A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells.Cell2017
29262623Small molecule inhibitor regorafenib inhibits RET signaling in neuroblastoma cells and effectively suppresses tumor growth in vivo.Oncotarget2017
27903968Novel Src/Abl tyrosine kinase inhibitor bosutinib suppresses neuroblastoma growth via inhibiting Src/Abl signaling.Oncotarget2017
27902463Novel multi-targeted ErbB family inhibitor afatinib blocks EGF-induced signaling and induces apoptosis in neuroblastoma.Oncotarget2017
26786851Novel ALK inhibitor AZD3463 inhibits neuroblastoma growth by overcoming crizotinib resistance and inducing apoptosis.Sci Rep2016
26660446Loss of c-Kit and bone marrow failure upon conditional removal of the GATA-2 C-terminal zinc finger domain in adult mice.Eur J Haematol2016
27610572A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells.Cell2016
27599572TAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cells.Sci Rep2016
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Collaborators

Xiao-Nan Li
Northwestern University
Co-authored papers 14
Lin Qi
Xiangya Hospital of Central South University
Co-authored papers 13
Patricia Baxter
Texas Children's Cancer Center, Baylor College of Medicine
Co-authored papers 13
Frank K Braun
University Hospital Regensburg
Co-authored papers 13
Holly Lindsay
Texas Children's Cancer Center, Baylor College of Medicine
Co-authored papers 12
Sibo Zhao
Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine
Co-authored papers 12
Murali Chintagumpala
Texas Children's Cancer Center, Baylor College of Medicine
Co-authored papers 8
Aviv Regev
Broad Institute of MIT and Harvard
Co-authored papers 7
Orit Rozenblatt-Rosen
Co-authored papers 6
Ching C Lau
Baylor College of Medicine
Co-authored papers 5
Asaf Madi
Co-authored papers 4
Itai Yanai
Institute for Systems Genetics NYU Grossman School of Medicine
Co-authored papers 2
Donald W Parsons
Texas Children's Hospital
Co-authored papers 2
Tak W Mak
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Malcolm A Smith
National Cancer Institute
Co-authored papers 2
Gregory P Way
Broad Institute of MIT and Harvard
Co-authored papers 1
Yu-Yun Du
Sun Yat-sen University Cancer Center
Co-authored papers 1
Jonas Nance
Cancer Center, Texas Tech University Health Sciences Center School of Medicine
Co-authored papers 1
Susan G Hilsenbeck
Co-authored papers 1
Jo Lynne Rokita
Co-authored papers 1
Yael P Mosse
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 1
Sebastian Brabetz
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 1
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 1
Harshavardhan Doddapaneni
Baylor College of Medicine
Co-authored papers 1
Marcus Bosenberg
Yale School of Medicine
Co-authored papers 1
Howard L Weiner
Co-authored papers 1
Dias Kurmashev
Greehey Children's Cancer Research Institute
Co-authored papers 1
Hannah McCalmont
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 1
Gregory J Gatto
Co-authored papers 1
Stephen T C Wong
Houston Methodist Research Institute
Co-authored papers 1
Release 1.2