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Author Details

Matthias Farlik
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
2007
52
26
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36646694Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species.Nat Commun2023
37612029The Human Skin Cell Atlas: Mapping the Organ at Unprecedented Depth.J Invest Dermatol2023
37675143Non-IgE-reactive allergen peptides deteriorate the skin barrier in house dust mite-sensitized atopic dermatitis patients.Front Cell Dev Biol2023
37249233Biallelic NFATC1 mutations cause an inborn error of immunity with impaired CD8+ T-cell function and perturbed glycolysis.Blood2023
37344156Cytokine-directed cellular cross-talk imprints synovial pathotypes in rheumatoid arthritis.Ann Rheum Dis2023
37210042Single-cell RNA sequencing defines disease-specific differences between chronic nodular prurigo and atopic dermatitis.J Allergy Clin Immunol2023
37002794Single-cell RNA sequencing analysis of a COVID-19-associated maculopapular rash in a patient with psoriasis treated with ustekinumab.J Dermatol2023
37365178Single-cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis.Nat Commun2023
34997067Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales.Sci Rep2022
35769924Processing human skin samples for single-cell assays.STAR Protoc2022
35504910DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases.Nat Commun2022
35750138Soluble TREM2 levels reflect the recruitment and expansion of TREM2<sup>+</sup> macrophages that localize to fibrotic areas and limit NASH.J Hepatol2022
36512641Stress signaling boosts interferon-induced gene transcription in macrophages.Sci Signal2022
35278628Schwann cells contribute to keloid formation.Matrix Biol2022
34320169A STAT5B-CD9 axis determines self-renewal in hematopoietic and leukemic stem cells.Blood2021
33664060SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8<sup>+</sup> T cell responses.Sci Immunol2021
34583709Single-cell RNA sequencing reveals markers of disease progression in primary cutaneous T-cell lymphoma.Mol Cancer2021
34813775Delayed antiretroviral therapy in HIV-infected individuals leads to irreversible depletion of skin- and mucosa-resident memory T cells.Immunity2021
34018188Single-cell RNA sequencing profiling in a patient with discordant primary cutaneous B-cell and T-cell lymphoma reveals micromilieu-driven immune skewing.Br J Dermatol2021
33968070Single-Cell RNA Sequencing Reveals Tissue Compartment-Specific Plasticity of Mycosis Fungoides Tumor Cells.Front Immunol2021
34155196Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3.Nat Commun2021
32375897Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets.Genome Biol2020
31996669Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL.Nat Commun2020
31750562Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants.EMBO J2020
31735910Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy.Mol Psychiatry2020
33067380A discrete subset of epigenetically primed human NK cells mediates antigen-specific immune responses.Sci Immunol2020
32499648Molecular design of hypothalamus development.Nature2020
30472157Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency.Cell Stem Cell2019
31345789Epigenomics and Single-Cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis.Cancer Discov2019
31171666Spatiotemporal structure of cell fate decisions in murine neural crest.Science2019
31133746MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.Nat Genet2019
30718299NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity.J Immunol2019
29200404STAT5BN642H is a driver mutation for T cell neoplasia.J Clin Invest2018
29804890An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion.Cell Stem Cell2018
29899063CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.Cancer Discov2018
27991900Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.Nat Neurosci2017
28498368It is a differentiation game: STAT5 in a new role.Cell Death Differ2017
27916275Artemisinins Target GABA<sub>A</sub> Receptor Signaling and Impair α Cell Identity.Cell2017
26691212Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep2016
27867036DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation.Cell Stem Cell2016
27492475Specification of tissue-resident macrophages during organogenesis.Science2016
27346425Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks.Nat Commun2016
27212022Multi-Omics of Single Cells: Strategies and Applications.Trends Biotechnol2016
27072894Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time.Biotechnol Bioeng2016
25732828Single-cell DNA methylome sequencing and bioinformatic inference of epigenomic cell-state dynamics.Cell Rep2015
26673328Differential DNA Methylation Analysis without a Reference Genome.Cell Rep2015
26146080Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex.Cell Rep2015
25912690Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern.Dev Biol2015
22252317Contribution of a TANK-binding kinase 1-interferon (IFN) regulatory factor 7 pathway to IFN-γ-induced gene expression.Mol Cell Biol2012
21349431Type I interferon inhibits interleukin-1 production and inflammasome activation.Immunity2011
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Collaborators

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 30
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 7
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 6
University of Salzburg
Co-authored papers 6
University of Vienna
Co-authored papers 6
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Co-authored papers 5
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Co-authored papers 4
School of Public Health, Imperial College London
Co-authored papers 4
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Co-authored papers 4
University of Virginia
Co-authored papers 3
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 3
Karolinska Institute
Co-authored papers 2
Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna
Co-authored papers 2
Children's Cancer Research Institute
Co-authored papers 2
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 2
Institut fur Experimentelle und Angewandte Physik, University of Regensburg
Co-authored papers 1
Co-authored papers 1
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University of Cambridge
Co-authored papers 1
Centre Hospitalo-Universitaire de Rouen
Co-authored papers 1
St. Anna Children's Cancer Research Institute (CCRI)
Co-authored papers 1
National Institute on Aging, National Institutes of Health
Co-authored papers 1
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Stockholm University
Co-authored papers 1
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Institute of Genetics and Cancer, University of Edinburgh
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Pennsylvania State University, University Park
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