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Author Details
Full Name
Juan Carlos Izpisua Belmonte
Affiliation
Inc., Salk Institute for Biological Studies
ORCID
Career Start Year
1989
Papers
510
H Index
112
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37158785
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner.
Protein Cell
2024
36929025
A single-nucleus transcriptomic atlas of primate testicular aging reveals exhaustion of the spermatogonial stem cell reservoir and loss of Sertoli cell homeostasis.
Protein Cell
2023
37561875
DNA methylation networks underlying mammalian traits.
Science
2023
37910499
Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging.
Cell Rep
2023
37907096
CHIT1-positive microglia drive motor neuron ageing in the primate spinal cord.
Nature
2023
37556833
Hepatocyte reprogramming in liver regeneration: Biological mechanisms and applications.
FEBS J
2023
37521327
MAVS Antagonizes Human Stem Cell Senescence as a Mitochondrial Stabilizer.
Research (Wash D C)
2023
37898124
Decoding aging-dependent regenerative decline across tissues at single-cell resolution.
Cell Stem Cell
2023
37550514
Chemical fast track to induced pluripotency.
Nat Cell Biol
2023
37832549
Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation.
Cell Stem Cell
2023
37783815
SIRT2 counteracts primate cardiac aging via deacetylation of STAT3 that silences CDKN2B.
Nat Aging
2023
37935676
SGF29 nuclear condensates reinforce cellular aging.
Cell Discov
2023
37674040
Author Correction: Universal DNA methylation age across mammalian tissues.
Nat Aging
2023
37563227
Universal DNA methylation age across mammalian tissues.
Nat Aging
2023
37393339
Rapid degeneration of iPSC-derived motor neurons lacking Gdap1 engages a mitochondrial-sustained innate immune response.
Cell Death Discov
2023
37118553
m<sup>6</sup>A epitranscriptomic regulation of tissue homeostasis during primate aging.
Nat Aging
2023
37285263
Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration.
Protein Cell
2023
37014011
Quantitative haplotype-resolved analysis of mitochondrial DNA heteroplasmy in Human single oocytes, blastoids, and pluripotent stem cells.
Nucleic Acids Res
2023
37199024
SESN1 is a FOXO3 effector that counteracts human skeletal muscle ageing.
Cell Prolif
2023
36999592
Single-cell individual full-length mtDNA sequencing by iMiGseq uncovers unexpected heteroplasmy shifts in mtDNA editing.
Nucleic Acids Res
2023
37261952
The circadian clock CRY1 regulates pluripotent stem cell identity and somatic cell reprogramming.
Cell Rep
2023
37261950
Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging.
Cell Rep
2023
36754048
Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice.
Cell
2023
36921027
Single-nucleus profiling unveils a geroprotective role of the FOXO3 in primate skeletal muscle aging.
Protein Cell
2023
36747595
A single-cell transcriptomic atlas of exercise-induced anti-inflammatory and geroprotective effects across the body.
Innovation (Camb)
2023
36610399
Resurrection of endogenous retroviruses during aging reinforces senescence.
Cell
2023
36933008
Single-cell transcriptomic atlas of mouse cochlear aging.
Protein Cell
2023
34342820
Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis.
Protein Cell
2022
35845171
Opening up the black box of human cell plasticity.
Innovation (Camb)
2022
35476977
In vivo partial cellular reprogramming enhances liver plasticity and regeneration.
Cell Rep
2022
35613617
Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues.
Cell Stem Cell
2022
35613614
Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging.
Dev Cell
2022
35790810
Towards capturing of totipotency.
Cell Res
2022
35752626
Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Nat Commun
2022
37193050
Deciphering aging at three-dimensional genomic resolution.
Cell Insight
2022
37118377
In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice.
Nat Aging
2022
37118068
FOXM1 delays senescence and extends lifespan.
Nat Aging
2022
37117743
Destabilizing heterochromatin by APOE mediates senescence.
Nat Aging
2022
36075901
Author Correction: Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Nat Commun
2022
35941369
A complex epigenome-splicing crosstalk governs epithelial-to-mesenchymal transition in metastasis and brain development.
Nat Cell Biol
2022
36261013
A stem cell aging framework, from mechanisms to interventions.
Cell Rep
2022
35947677
<i>LINE-1</i> RNA causes heterochromatin erosion and is a target for amelioration of senescent phenotypes in progeroid syndromes.
Sci Transl Med
2022
35977506
APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-κB activation.
Cell Rep
2022
35879609
Why it is important to study human-monkey embryonic chimeras in a dish.
Nat Methods
2022
35102134
Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor.
Cell Discov
2022
35286396
BMAL1 moonlighting as a gatekeeper for LINE1 repression and cellular senescence in primates.
Nucleic Acids Res
2022
35309931
Myc Supports Self-Renewal of Basal Cells in the Esophageal Epithelium.
Front Cell Dev Biol
2022
35180387
Time matters: Human blastoids resemble the sequence of blastocyst development.
Cell
2022
35303745
Rejuvenation of Tissue Stem Cells by Intrinsic and Extrinsic Factors.
Stem Cells Transl Med
2022
35017655
Transcriptomic profiling fuels the derivation of stable pig epiblast stem cells.
Cell Res
2022
1 - 50 of 510
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King Mongkut's University of Technology Thonburi
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King Abdullah University of Science and Technology
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Swiss Federal Institute of Technology
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Harvard Medical School
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Center for Epigenomics, University of California San Diego
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