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Author Details

Hector Viadiu
All India Institute of Medical Sciences
1995
24
15
PMIDPaper TitleJournal TitlePublished Year
35217090Deciphering the mechanism of p73 recognition of p53 response elements using the crystal structure of p73-DNA complexes and computational studies.Int J Biol Macromol2022
35217090Deciphering the mechanism of p73 recognition of p53 response elements using the crystal structure of p73-DNA complexes and computational studies.Int J Biol Macromol2022
30023688Spiked Genes: A Method to Introduce Random Point Nucleotide Mutations Evenly throughout an Entire Gene Using a Complete Set of Spiked Oligonucleotides for the Assembly.ACS Omega2017
30023688Spiked Genes: A Method to Introduce Random Point Nucleotide Mutations Evenly throughout an Entire Gene Using a Complete Set of Spiked Oligonucleotides for the Assembly.ACS Omega2017
27132513TNF-α modulates genome-wide redistribution of οNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer.Oncogene2016
27132513TNF-α modulates genome-wide redistribution of οNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer.Oncogene2016
26529454Sequence Variation in the Response Element Determines Binding by the Transcription Factor p73.Biochemistry2015
26529454Sequence Variation in the Response Element Determines Binding by the Transcription Factor p73.Biochemistry2015
25201192Structural studies on mechanisms to activate mutant p53.Subcell Biochem2014
25201192Structural studies on mechanisms to activate mutant p53.Subcell Biochem2014
23243311Crystal structures of the DNA-binding domain tetramer of the p53 tumor suppressor family member p73 bound to different full-site response elements.J Biol Chem2013
23892287Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code.Nucleic Acids Res2013
23463580EEC- and ADULT-associated TP63 mutations exhibit functional heterogeneity toward P63 responsive sequences.Hum Mutat2013
23243311Crystal structures of the DNA-binding domain tetramer of the p53 tumor suppressor family member p73 bound to different full-site response elements.J Biol Chem2013
23892287Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code.Nucleic Acids Res2013
23463580EEC- and ADULT-associated TP63 mutations exhibit functional heterogeneity toward P63 responsive sequences.Hum Mutat2013
22474346Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.Proc Natl Acad Sci U S A2012
22474346Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.Proc Natl Acad Sci U S A2012
23025236The tetramer of p53 in the absence of DNA forms a relaxed quaternary state.Biochemistry2012
23025236The tetramer of p53 in the absence of DNA forms a relaxed quaternary state.Biochemistry2012
20833632Asymmetric DNA recognition by the OkrAI endonuclease, an isoschizomer of BamHI.Nucleic Acids Res2011
20833632Asymmetric DNA recognition by the OkrAI endonuclease, an isoschizomer of BamHI.Nucleic Acids Res2011
21936505Nanodiscs versus macrodiscs for NMR of membrane proteins.Biochemistry2011
21936505Nanodiscs versus macrodiscs for NMR of membrane proteins.Biochemistry2011
18991721Molecular architecture of tumor suppressor p53.Curr Top Med Chem2008
18991721Molecular architecture of tumor suppressor p53.Curr Top Med Chem2008
17239399Projection map of aquaporin-9 at 7 A resolution.J Mol Biol2007
17239399Projection map of aquaporin-9 at 7 A resolution.J Mol Biol2007
15880121Domain structure of separase and its binding to securin as determined by EM.Nat Struct Mol Biol2005
15880121Domain structure of separase and its binding to securin as determined by EM.Nat Struct Mol Biol2005
16308566A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA.EMBO J2005
16308566A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA.EMBO J2005
12719261Energetic and structural considerations for the mechanism of protein sliding along DNA in the nonspecific BamHI-DNA complex.Biophys J2003
12719261Energetic and structural considerations for the mechanism of protein sliding along DNA in the nonspecific BamHI-DNA complex.Biophys J2003
12876363Crystallization of restriction endonuclease SfiI in complex with DNA.Acta Crystallogr D Biol Crystallogr2003
12876363Crystallization of restriction endonuclease SfiI in complex with DNA.Acta Crystallogr D Biol Crystallogr2003
10806094Crystallization of restriction endonuclease BamHI with nonspecific DNA.J Struct Biol2000
10882125Structure of BamHI bound to nonspecific DNA: a model for DNA sliding.Mol Cell2000
11073444Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification.Science2000
10806094Crystallization of restriction endonuclease BamHI with nonspecific DNA.J Struct Biol2000
10882125Structure of BamHI bound to nonspecific DNA: a model for DNA sliding.Mol Cell2000
11073444Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification.Science2000
9783752The role of metals in catalysis by the restriction endonuclease BamHI.Nat Struct Biol1998
9783752The role of metals in catalysis by the restriction endonuclease BamHI.Nat Struct Biol1998
7822310Substitution of Asp for Asn at position 132 in the active site of TEM beta-lactamase. Activity toward different substrates and effects of neighboring residues.J Biol Chem1995
7822311A new TEM beta-lactamase double mutant with broadened specificity reveals substrate-dependent functional interactions.J Biol Chem1995
7822310Substitution of Asp for Asn at position 132 in the active site of TEM beta-lactamase. Activity toward different substrates and effects of neighboring residues.J Biol Chem1995
7822311A new TEM beta-lactamase double mutant with broadened specificity reveals substrate-dependent functional interactions.J Biol Chem1995
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Collaborators

Xavier Soberón
Co-authored papers 2
Yansong Bian
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Christina Yau
University of California San Francisco
Co-authored papers 1
Austin K Mattox
Howard Hughes Medical Institute
Co-authored papers 1
Minyoung Jang
Columbia University Irving Medical Center
Co-authored papers 1
Christopher C Benz
Buck Institute for Research on Aging
Co-authored papers 1
Robert L Walker
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Zhong Chen
National Institute on Deafness and Other Communication Disorders
Co-authored papers 1
Hai Lu
The Fifth Affiliated Hospital, Sun Yat-sen University
Co-authored papers 1
Emiko Sano
0 SW US Veterans Hospital Road
Co-authored papers 1
Rose-Anne Romano
State University of New York at Buffalo
Co-authored papers 1
Xinping Yang
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Hao Sun
University of Illinois at Urbana-Champaign
Co-authored papers 1
Joshua M Stuart
University of California at Santa Cruz
Co-authored papers 1
Harel Weinstein
Institute for Computational Biomedicine
Co-authored papers 1
Wenming Xiao
Human Phenome Institute and Shanghai Cancer Center, Fudan University
Co-authored papers 1
Lai Wei
Clinical Immunology Section, National Eye Institute
Co-authored papers 1
Michael G Rosenfeld
University of California San Diego
Co-authored papers 1
Sean Davis
Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington
Co-authored papers 1
Susan R Davis
Co-authored papers 1
Kristen Jepsen
Institute for Genomic Medicine, University of California San Diego
Co-authored papers 1
Sam Ng
University of Adelaide
Co-authored papers 1
Steven K Lee
National Institute on Deafness and Other Communication Disorders
Co-authored papers 1
Han Si
Hubei Engineering Research Center for Bio-enzyme Catalysis, Hubei University
Co-authored papers 1
Satrajit Sinha
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo
Co-authored papers 1
Bin Yan
The University of Hong Kong
Co-authored papers 1
Carter Van Waes
National Institute of Deafness and Other Communication Disorders
Co-authored papers 1
Paul S Meltzer
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
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