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Author Details
Full Name
Gordon S Rule
Affiliation
Carnegie Mellon University
ORCID
Career Start Year
1978
Papers
67
H Index
27
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37632831
Direct observation of negative cooperativity in a detoxification enzyme at the atomic level by Electron Paramagnetic Resonance spectroscopy and simulation.
Protein Sci
2023
35984406
Rational Control of Protein-Protein Interactions with Protein-ATRP-Generated Protease-Sensitive Polymer Cages.
Biomacromolecules
2022
34048258
Protein Dynamics Is Altered by a High Surface Density of Atomic Transfer Radical Polymerization Polymers.
Langmuir
2021
33682244
Conformational diversity defines substrate specificity of thymidylate/uridylate kinase from Candida albicans.
Proteins
2021
32910837
Double Histidine Based EPR Measurements at Physiological Temperatures Permit Site-Specific Elucidation of Hidden Dynamics in Enzymes.
Angew Chem Int Ed Engl
2020
31934749
dGMP Binding to Thymidylate Kinase from <i>Plasmodium falciparum</i> Shows Half-Site Binding and Induces Protein Dynamics at the Dimer Interface.
Biochemistry
2020
32064397
Stabilization of Active Site Dynamics Leads to Increased Activity with 3'-Azido-3'-deoxythymidine Monophosphate for F105Y Mutant Human Thymidylate Kinase.
ACS Omega
2020
29272745
The Cu<sup>2+</sup>-nitrilotriacetic acid complex improves loading of α-helical double histidine site for precise distance measurements by pulsed ESR.
J Magn Reson
2018
29414705
ESR Resolves the C Terminus Structure of the Ligand-free Human Glutathione S-Transferase A1-1.
Biophys J
2018
29684273
Interaction of α-Thymidine Inhibitors with Thymidylate Kinase from Plasmodium falciparum.
Biochemistry
2018
29562132
Design of Bivalent Nucleic Acid Ligands for Recognition of RNA-Repeated Expansion Associated with Huntington's Disease.
Biochemistry
2018
28742342
The Structure of Thymidylate Kinase from Candida albicans Reveals a Unique Structural Element.
Biochemistry
2017
28677395
Dual Lifetimes for Complexes between Glutathione-S-transferase (hGSTA1-1) and Product-like Ligands Detected by Single-Molecule Fluorescence Imaging.
Biochemistry
2017
27786446
Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein-DNA Complex.
Biochemistry
2016
23771591
Divide and conquer is always best: sensitivity of methyl correlation experiments.
J Biomol NMR
2013
22390683
A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry
2012
22955930
In support of the BMRB.
Nat Struct Mol Biol
2012
22039762
Specific labeling of threonine methyl groups for NMR studies of protein-nucleic acid complexes.
Biochemistry
2011
16908525
Sequence-specific interactions in the RNA-binding domain of Escherichia coli transcription termination factor Rho.
J Biol Chem
2006
16277508
Stable triplet of uracil-uracil basepairs in a small antisense RNA.
J Am Chem Soc
2005
15182170
Glutathione induces helical formation in the carboxy terminus of human glutathione transferase A1-1.
Biochemistry
2004
12852758
Isolation, structure, synthesis, and bioactivity of a novel putative insulin mediator. A galactosamine chiro-inositol pseudo-disaccharide Mn2+ chelate with insulin-like activity.
J Med Chem
2003
12566996
Data requirements for reliable chemical shift assignments in deuterated proteins.
J Biomol NMR
2003
12566995
MONTE: An automated Monte Carlo based approach to nuclear magnetic resonance assignment of proteins.
J Biomol NMR
2003
12054778
The crystal structure of a major dust mite allergen Der p 2, and its biological implications.
J Mol Biol
2002
11134039
Hydrogen exchange nuclear magnetic resonance spectroscopy mapping of antibody epitopes on the house dust mite allergen Der p 2.
J Biol Chem
2001
11258945
Changes in Ca2+ affinity upon activation of Agkistrodon piscivorus piscivorus phospholipase A2.
Biochemistry
2001
11570866
Disorder-to-order transition of the active site of human class Pi glutathione transferase, GST P1-1.
Biochemistry
2001
10858281
Ligand-induced changes in the structure and dynamics of a human class Mu glutathione S-transferase.
Biochemistry
2000
10479573
A J(CH)-modulated 2D (HACACO)NH pulse scheme for quantitative measurement of (13)C(alpha)-(1)H(alpha) couplings in (15)N, (13)C-labeled proteins.
J Magn Reson
1999
9925789
Solution structure of the carboxyl terminus of a human class Mu glutathione S-transferase: NMR assignment strategies in large proteins.
J Mol Biol
1999
9761709
Unambiguous correlations of backbone amide and aliphatic gamma resonances in deuterated proteins.
J Magn Reson
1998
9587002
The NMR structure of the RNA binding domain of E. coli rho factor suggests possible RNA-protein interactions.
Nat Struct Biol
1998
9586995
Crystal structure of the RNA-binding domain from transcription termination factor rho.
Nat Struct Biol
1998
9740730
Effect of deuteration on the accuracy of HN-HN distance constraints.
J Magn Reson
1998
9737847
Tertiary structure of the major house dust mite allergen Der p 2: sequential and structural homologies.
Biochemistry
1998
9341122
Expression and secondary structure determination by NMR methods of the major house dust mite allergen Der p 2.
J Biol Chem
1997
9130493
Antigenic and molecular structure of the mite allergen Der p 2.
Int Arch Allergy Immunol
1997
9245602
Reduction in the amide hydrogen exchange rates of an anti-lysozyme Fv fragment due to formation of the Fv-lysozyme complex.
J Mol Biol
1997
8636987
Global changes in amide hydrogen exchange rates for a protein antigen in complex with three different antibodies.
J Mol Biol
1996
9008362
1H, 15N and 13C resonance assignments and secondary structure determination of the RNA-binding domain of E.coli rho protein.
J Biomol NMR
1996
8616268
1H, 15N and 13C resonance assignments and secondary structure of group II phospholipase A2 from Agkistrodon piscivorus piscivorus: presence of an amino-terminal helix in solution.
J Biomol NMR
1996
7725337
Expression of glutathione S-transferase-cardiotoxin fusion protein in Escherichia coli.
Toxicon
1994
8182750
Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity.
J Mol Biol
1994
8182052
Two distinct types of cardiotoxin as revealed by the structure and activity relationship of their interaction with zwitterionic phospholipid dispersions.
J Biol Chem
1994
8347605
Solution structure of cardiotoxin V from Naja naja atra.
Biochemistry
1993
1382591
Long-range changes in a protein antigen due to antigen-antibody interaction.
Biochemistry
1992
1642888
Use of petroleum jelly for sealing coverslips in crystallization trials.
Biotechniques
1992
1550817
Mapping the substrate-binding site of a human class mu glutathione transferase using nuclear magnetic resonance spectroscopy.
Biochemistry
1992
1600091
Application of site-directed mutagenesis in nuclear magnetic resonance spectroscopy.
Biophys J
1992
1 - 50 of 67
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row(s) 1 - 30 of 30
Collaborators
Chien Ho
Carnegie Mellon University
Co-authored papers
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Michael Levitt
Stanford University
Co-authored papers
2
Roberto Poljak
Co-authored papers
2
Roberto R Gil
Carnegie Mellon University
Co-authored papers
2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers
1
William R Pearson
University of Virginia
Co-authored papers
1
Lewis E Kay
University of Toronto
Co-authored papers
1
Kylie J Walters
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers
1
Michael R Gryk
University of Illinois
Co-authored papers
1
Walter J Chazin
and Center for Structural Biology, Vanderbilt University
Co-authored papers
1
Bernd Reif
Technische Universitat Munchen (TUM)
Co-authored papers
1
Matthew P Crump
University of Bristol
Co-authored papers
1
Alexander P Golovanov
The University of Manchester
Co-authored papers
1
David A Case
Rutgers University
Co-authored papers
1
Oliver F Lange
Center for Integrated Protein Science, Technische Universitat Munchen
Co-authored papers
1
Gordon C K Roberts
Leicester Institute of Structural and Chemical Biology, University of Leicester
Co-authored papers
1
Josep Rizo
University of Texas Southwestern Medical Center
Co-authored papers
1
Mike P Williamson
The University of Sheffield
Co-authored papers
1
Lu-Yun Lian
Institute of Systems, The University of Liverpool
Co-authored papers
1
Mary Patricia Massicotte
Stollery Children's Hospital, University of Alberta
Co-authored papers
1
Igor L Barsukov
Institute of Integrative Biology, University of Liverpool
Co-authored papers
1
David E Shaw
Columbia University
Co-authored papers
1
Ad Bax
National Institutes of Health
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Patrick C A van der Wel
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